Creating biological models to study liver diseases and tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on developing preclinical translational models to better understand chronic liver diseases and tumors, including non-alcoholic steatohepatitis and liver cancer. The research involves collecting blood samples and biopsies from patients undergoing surgery or diagnostic tests to analyze the liver's microenvironment and disease mechanisms. By utilizing advanced techniques like single cell RNA sequencing, the study aims to identify new therapeutic targets and improve treatment responses for these conditions. The ultimate goal is to enhance the understanding of liver diseases and facilitate the development of effective therapies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients

   * diagnosed with chronic liver disease (viral or not)
   * diagnosed with at least one liver nodule for which a biopsy is planned as part of the care
   * for hepatobiliary surgery planned as part of care
   * for locoregional treatment for HCC is indicated
2. Patients able to receive and understand information relating to the study and give their written informed consent
3. Patients affiliated to the French social security system

Exclusion Criteria:

1. Minor patients
2. Patients under legal protection,
3. Patients subject to legal protection or unable to express their consent,
4. Patients in a situation of social fragility,
5. Pregnant or breastfeeding woman,
6. No signing of informed consent.

Where it's running

• PU-PH, Directeur de l'UMR_S1110 Unité Inserm d'affiliation : UMR_S1110
  Strasbourg, France Recruiting

Study contacts

• Study coordinator: Thomas BAUMERT, DR
• Email: thomas.baumert@unistra.fr
• Phone: 03 68 85 37 03

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.