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Clinical trials and research at Icahn School of Medicine at Mount Sinai

• 167Clinical trials
• 1523NIH research projects
• 3New in 30 days
• 8Countries

Newest trials

All recruiting trials (newest 150 of 167)

• PRP injection for female sexual function

  This trial tests whether a patient’s own PRP injection into the front vaginal wall can improve sexual function in women with sexual dysfunction.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07920900

• Dupilumab for Major Depressive Disorder

  This study tests whether dupilumab can engage immune targets in adults with major depressive disorder to see if it can help with depressive symptoms.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07908563

• Parkinson’s Risk in Gaucher Disease Type 1

  This study tests how Parkinson’s risk relates to GBA1-related Gaucher disease in adults over 40, by collecting detailed clinical data and samples for future research.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07886879

• Personalized Exercise Recommendations for Chronic Pelvic Pain

  This study tests if an AI-powered, personalized exercise plan can help people with chronic pelvic pain see if tailored workouts work better than standard guidance.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07810218

• Buprenorphine vs morphine for pain control after cesarean delivery

  This study tests whether intrathecal buprenorphine provides better postcesarean pain relief than morphine for women undergoing a planned cesarean delivery.

  Recruiting Phase 4 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07786012

• SCC Deep Brain Stimulation for Bipolar Depression in Bipolar I Patients

  A small study tests whether deep brain stimulation of the subcallosal cingulate can help people with bipolar I depression who have not improved with other treatments, while monitoring brain signals to watch for manic switches.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07745374

• Natural history of MADD: what happens over time in people with this condition

  This study follows people with MADD over time to see how the condition changes, what symptoms appear, and which biomarkers and patient-reported outcomes are meaningful.

  Recruiting Icahn School of Medicine at Mount Sinai · Aurora, Colorado and 1 other locations · NCT07734090

• Tract Closure with Hemostatic Agent in PCNL

  This trial tests whether applying a hemostatic agent during tract closure in PCNL helps reduce blood loss compared with balloon tamponade alone.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07668817

• Understanding CAR-T Toxicities After Cilta-Cel in Multiple Myeloma

  This observational study tests how patients with multiple myeloma respond to cilta-cel treatment by tracking toxicities and trying to spot biomarkers to guide care.

  Recruiting at 3 sites Icahn School of Medicine at Mount Sinai · San Francisco, California and 2 other locations · NCT07665307

• Positioning strategies to treat proximal ureteral stones

  This study tests whether reverse Trendelenburg or T-tilt positioning during ureteroscopy help treat proximal ureteral stones more efficiently in adults.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07601932

• Combination therapy for Long COVID symptoms using valacyclovir, celecoxib, and Paxlovid

  This study tests whether a three-drug combination can reduce Long COVID symptoms in adults compared with a placebo.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07597902

• Understanding and Targeting Self-Regulatory Control in Bulimia Nervosa

  In women with bulimia nervosa, this study tests whether real-time brain feedback during eating, paired with a 4-week text-message program, can help improve self-control and reduce symptoms.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07581158

• NMN in DHDDS-CDG: is this safe and tolerable for people with DHDDS-CDG?

  This study tests whether taking NMN daily is safe and tolerable for people with DHDDS-CDG.

  Recruiting Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07572825

• Suzetrigine to reduce pain after total knee replacement

  This trial tests whether giving Suzetrigine before surgery helps adults having total knee replacement use fewer opioids and have less postoperative pain.

  Recruiting Phase 3 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07548385

• MDMA-assisted therapy for bulimia nervosa

  This study tests whether MDMA-assisted therapy can help people with bulimia nervosa over a 10-week period.

  Recruiting Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07542145

• Suzetrigine added to multimodal opioid-sparing pain care for heart and weight-loss surgery

  This trial will test whether adding suzetrigine to standard multimodal pain care lowers opioid use and pain after bariatric or open-heart (sternotomy) surgery in adults.

  Recruiting Phase 3 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07539623

• New ways to manage high blood pressure for high-risk emergency department patients

  It will try using community health workers to help emergency department patients in New York City with uncontrolled high blood pressure by connecting them to local social services.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07539597

• Pulsed field ablation for atrial fibrillation in underrepresented minority patients

  This registry will test how well Boston Scientific pulsed field ablation works and how safe it is for Black, Hispanic, Asian, and other underrepresented adults with paroxysmal or persistent atrial fibrillation.

  Recruiting at 2 sites Icahn School of Medicine at Mount Sinai · New York, New York and 1 other locations · NCT07535268

• Deucravacitinib for scarring hair loss (frontal fibrosing and central centrifugal alopecia)

  This trial will test whether taking deucravacitinib once daily for 48 weeks helps adults with frontal fibrosing alopecia or central centrifugal cicatricial alopecia.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07508488

• Blocking IL-6 with tocilizumab for depression

  This study will test whether subcutaneous injections of the anti‑IL‑6 drug tocilizumab can improve reward‑related brain activity and depressive symptoms in adults with major depressive disorder who have high monocyte counts.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07493317

• Topical delgocitinib 2% cream for Lichen Planopilaris and Central Centrifugal Cicatricial Alopecia

  This trial tests whether applying 2% delgocitinib cream twice daily is safe and changes scalp biomarkers in adults with Lichen Planopilaris or Central Centrifugal Cicatricial Alopecia over 48 weeks.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07487948

• Etrasimod to Help Prevent Pouchitis After Pouch Surgery

  This study tests whether etrasimod, taken daily, can help prevent pouchitis in adults who had total proctocolectomy with ileal-pouch anal anastomosis for ulcerative colitis and are currently in remission.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07486921

• Prototype CT tools for minimally invasive intracerebral hemorrhage evacuation

  This project will test two Siemens prototype CT tools—a perfusion feature and an automatic hemorrhage detector—to see if they help doctors planning and performing minimally invasive brain-bleed (intracerebral hemorrhage) evacuation in adults.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07455201

• Pacritinib and Selinexor in JAK-inhibitor naive myelofibrosis with anemia and low platelets

  This trial tests whether combining pacritinib and selinexor helps patients with myelofibrosis who have anemia and low platelets and have not yet tried a JAK inhibitor.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · Westwood, Kansas and 2 other locations · NCT07447817

• Group-based care for managing hypertension and diabetes in Nepal

  A group-based care program is being tested to see if it helps people with hypertension and diabetes in four municipalities in Nepal better control their blood pressure and glucose.

  Recruiting Icahn School of Medicine at Mount Sinai · Dhulikhel · NCT07439380

• Vestibulocortical Stimulation for Fibromyalgia: A Quick Bedside Test

  This trial tests whether a single bedside vestibulocortical stimulation session using temperate water can reduce pain and improve quality of life in adults with fibromyalgia compared with a sham procedure.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07423377

• Social isolation and aging in people with schizophrenia

  This project will test whether long-term social isolation helps explain faster physical aging in people aged 40–70 with schizophrenia who took part in earlier research.

  Recruiting at 4 sites Icahn School of Medicine at Mount Sinai · Hartford, Connecticut and 3 other locations · NCT07419321

• Non-invasive vagus nerve stimulation paired with arm rehab for teens with spastic cerebral palsy

  This trial tests non-invasive vagus nerve stimulation paired with upper-extremity rehabilitation to see if it safely improves arm and hand function in adolescents (12–17) with spastic cerebral palsy.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07394608

• Tiered Palliative Care for Patients with Advanced Heart Failure or Cancer

  This trial tests a home-based, tiered palliative care program to see if more personalized support improves symptoms and quality of life for adults with advanced heart failure or certain advanced cancers.

  Recruiting at 5 sites Icahn School of Medicine at Mount Sinai · Astoria, New York and 4 other locations · NCT07391956

• The Coma Family Program: a resilience program for caregivers of patients with severe brain injury

  This program tests whether the Coma Family Program can better reduce emotional distress in caregivers of patients with severe acute brain injury compared to a health education control.

  Recruiting at 3 sites Icahn School of Medicine at Mount Sinai · Baltimore, Maryland and 3 other locations · NCT07331324

• Imetelstat with azacitidine, with or without venetoclax, for relapsed AML

  This test adds imetelstat to azacitidine, sometimes with venetoclax, to see if it helps adults whose AML has come back or not responded to prior therapy.

  Recruiting Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07320235

• Mild electrical brain stimulation (tDCS) with cognitive training to reduce cocaine cravings.

  This trial will test whether brief sessions of mild electrical brain stimulation (tDCS) combined with cognitive reappraisal training can lower craving in adults receiving inpatient treatment for cocaine use disorder.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07318480

• Balt Coils with MMA Embolization for Chronic Subdural Hematoma

  This registry is testing whether using Balt coils during middle meningeal artery embolization is safe and helps patients with chronic subdural hematoma.

  Recruiting Icahn School of Medicine at Mount Sinai · Tucson, Arizona and 4 other locations · NCT07291427

• PSMA PET/CT plus MRI to find higher‑grade prostate cancer in men on active surveillance

  This study tries adding rhPSMA-7.3 (flotufolastat F18) PET/CT to standard mpMRI to see if it finds higher-grade prostate cancer in men on active surveillance.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07285057

• Nadunolimab to prevent progression of high-risk lung nodules

  This trial will test whether nadunolimab can shrink or stop growth of multifocal part-solid high-risk lung nodules in current or former heavy smokers (≥20 pack‑years).

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07284485

• Combination immunotherapy for chemotherapy‑resistant metastatic MSS colorectal cancer

  This trial will try a two‑drug immunotherapy combination (nadunolimab plus toripalimab) in adults whose metastatic, microsatellite‑stable colorectal cancer has stopped responding to standard chemotherapy.

  Recruiting Phase 1/2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07281716

• Cannabidiol and neuroimaging for stress response in young adults

  This trial will test whether a single dose of cannabidiol (CBD) changes stress responses in 18–25-year-olds with histories of early-life adversity and elevated stress.

  Recruiting Phase 1/2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07278505

• Neoadjuvant immunotherapy with Dupilumab and Toripalimab for MSS colorectal cancer with resectable liver metastases

  This study tests a pre-surgery treatment combining dupilumab and toripalimab in adults with microsatellite-stable colorectal cancer that has liver metastases, to see if it’s safe and can lead to major tumor response.

  Recruiting Phase 1/2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07277322

• Abrocitinib for eczema and patchy hair loss in people with Down syndrome

  This trial will test whether taking abrocitinib daily can help improve eczema or patchy hair loss in people with Down syndrome aged 12 and up.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07242638

• Preventing calcium oxalate kidney stones

  This test compares giving empiric preventive treatment right after kidney stone surgery to using 24-hour urine tests to guide treatment for people with calcium oxalate stones.

  Recruiting Phase 4 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07225764

• Alnuctamab treatment for refractory SLE

  This trial will test whether the experimental T-cell engager alnuctamab is safe and helps adults 18–60 with moderate-to-severe SLE that has not responded to standard treatments.

  Recruiting Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07219563

• Music therapy plus interactive recitals for children with depression

  This program will try 11 weekly music therapy sessions, with half of participants also joining interactive recitals, to see if these activities help children with depression and anxiety.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07218055

• Morning light therapy for ulcerative colitis with poor sleep

  This pilot will test whether one hour of morning light therapy can improve sleep and lower inflammation in adults with ulcerative colitis who have poor sleep and signs of active inflammation.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07207200

• Continuous glucose monitoring during late pregnancy and after delivery for gestational diabetes

  This study will collect Dexcom G7 glucose data from people with gestational diabetes during the third trimester and for two weeks after birth to see if those patterns predict an abnormal 6‑week postpartum oral glucose tolerance test.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07174245

• Recovering Together After Cardiac Arrest: a mind-body resilience program for survivors and caregivers.

  This project will try two brief mind-body programs to help cardiac arrest survivors and their caregivers reduce anxiety, depression, and emotional distress.

  Recruiting Icahn School of Medicine at Mount Sinai · Boston, Massachusetts and 1 other locations · NCT07143357

• Memory support program for older Chinese American adults with mild cognitive impairment

  This project will test whether the Memory Support System helps Mandarin- and Cantonese-speaking Chinese American older adults with mild cognitive impairment manage everyday memory and thinking challenges.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07142499

• MDMA-assisted therapy for mental healthcare providers in training

  This study will try a single MDMA-assisted therapy session (with one prep and one integration visit) in mental healthcare providers training to deliver MDMA therapy to see if it improves overall mental wellbeing and reduces burnout.

  Recruiting Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07102576

• Virtual reality to reduce pain during ultrasound-guided obstetric needle procedures

  This study will try virtual reality during ultrasound-guided needle procedures to see if it reduces pain and anxiety for obstetric patients.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07094451

• Cue-reactivity incubation and cognitive reappraisal in cocaine use disorder

  This project will see if practicing cognitive reappraisal reduces cue-triggered brain responses and cravings in people with cocaine use disorder who are early in abstinence.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07091877

• SeizEAR: in-ear device for detecting seizures

  This project will test whether a small in-ear device can safely detect seizures in adults first without epilepsy and then in people undergoing clinical scalp EEG for suspected temporal-lobe seizures.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07088835

• Methamphetamine cue-reactivity and cognitive reappraisal in men with methamphetamine use disorder

  This project will test whether cognitive reappraisal reduces methamphetamine cue-triggered brain and physiological responses during abstinence in men with methamphetamine use disorder and whether effects differ between men who have sex with men (MSM) and non-MSM.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07086014

• Combining atezolizumab and bevacizumab with Y-90 radioembolization to help people with liver cancer get to transplant

  This trial tests whether adding immunotherapy (atezolizumab plus bevacizumab) to Y-90 radioembolization can help people with hepatocellular carcinoma bridge to or be downstaged for liver transplant.

  Recruiting Phase 4 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07059494

• Prednisone to prevent recurrence of non-specific pleuritis

  This study tests whether a short course of prednisone can reduce recurrent fluid buildup in adults with non-specific pleuritis after pleural biopsy.

  Recruiting at 2 sites Early Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York and 1 other locations · NCT07039019

• Hormone therapy with darolutamide and pembrolizumab before prostate removal, then pembrolizumab after surgery for high-risk prostate cancer

  This trial will test whether giving androgen-deprivation therapy plus darolutamide and pembrolizumab before prostate removal, followed by pembrolizumab after surgery, helps men with genomically defined high-risk localized prostate cancer.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07027124

• Using EEG and computational models to better understand compulsivity in OCD

  This project will test whether combining EEG recordings with computational cognitive models can reveal distinct brain and behavior patterns in adults with OCD compared to adults without OCD.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07011901

• MIND diet for adults with multiple sclerosis

  This program will test whether following the MIND diet for one year helps brain health and reduces MS symptoms in adults with multiple sclerosis.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06992115

• Program to restore resilience and reduce PTSD after military sexual trauma or intimate partner violence with brain injury

  This trial tests whether adding a web-based emotion regulation program to exposure therapy helps female Veterans with military sexual trauma or intimate partner violence and a history of brain injury reduce PTSD symptoms.

  Recruiting Icahn School of Medicine at Mount Sinai · Houston, Texas · NCT06988787

• Low-dose sirolimus for adults with Long COVID (PASC)

  This trial will test whether low-dose sirolimus can reduce symptoms in adults who have had Long COVID for at least six months.

  Recruiting Phase 3 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06960928

• Using Transcranial Magnetic Stimulation to Treat Misophonia

  This study is testing if a brain treatment called TMS can help people with misophonia become more tolerant to certain annoying sounds.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06960083

• Nerve-sparing prostate surgery using micro-ultrasound guidance

  This study is testing a new approach to prostate surgery that uses advanced ultrasound technology to help men with localized prostate cancer keep their sexual function while effectively removing the cancer.

  Recruiting Phase 3 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06945315

• Using Timolol Solution to Heal Surgical Wounds Faster

  This study is testing if a special eye drop solution can help speed up the healing of surgical wounds on the legs after Mohs surgery compared to regular care.

  Recruiting Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06941467

• Cannabidiol added to methadone or buprenorphine for opioid recovery

  This trial will test whether adding cannabidiol (CBD) to methadone or buprenorphine helps people with opioid use disorder reduce craving and stop using illicit opioids.

  Recruiting at 2 sites Phase 3 Icahn School of Medicine at Mount Sinai · New York, New York and 1 other locations · NCT06940674

• Sensor-guided exercise program for people with atrial fibrillation

  This program will test whether a Fitbit-based, personalized exercise plan can reduce symptoms and episode burden in people with paroxysmal atrial fibrillation.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06938412

• Ruxolitinib treatment for acute graft-versus-host disease

  This study is testing if ruxolitinib can help people with acute graft-versus-host disease who haven't improved with regular steroid treatments.

  Recruiting at 10 sites Phase 2 Icahn School of Medicine at Mount Sinai · Duarte, California and 13 other locations · NCT06936566

• Comparing surveillance bronchoscopy to no surveillance after airway stenting

  This study is testing whether regular check-ups with a bronchoscopy after getting airway stents can help patients manage their condition better than not having these check-ups.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06935695

• Using Vagus Nerve Stimulation and Robotic Mobilization for Patients with Prolonged Disorders of Consciousness

  This study is testing if combining a special nerve stimulation treatment with robotic help to move can improve the recovery of patients who have been in a prolonged state of unconsciousness.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06930716

• Cannabidiol (CBD) treatment for adults with sickle cell disease

  This trial will try three doses of oral cannabidiol taken twice daily for 4 weeks in adults with sickle cell disease, compared with placebo, to see if it lowers inflammation and pain-related measures.

  Recruiting Phase 1/2 Icahn School of Medicine at Mount Sinai · Manhattan, New York · NCT06930703

• Atomoxetine for MC4R-related obesity

  This phase 2 study tests whether atomoxetine can help reduce obesity in people with MC4R-related genetic obesity compared with placebo.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York and 2 other locations · NCT06899178

• Psilocybin-assisted therapy for adults who are biological children of genocide survivors

  This project will test whether two supervised 25 mg doses of psilocybin plus preparation and integration therapy help adults who are biological children of genocide survivors reduce depression, anxiety, and stress.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06899165

• Continuous glucose monitoring to diagnose gestational diabetes

  A continuous glucose monitor will be tried to see if it can diagnose gestational diabetes in pregnant people between 24 and 32 weeks who receive prenatal care at Mount Sinai.

  Recruiting at 3 sites Icahn School of Medicine at Mount Sinai · New York, New York and 2 other locations · NCT06858787

• VR circadian reset to change REM sleep and reduce binge eating

  This trial uses a VR-based circadian reset program to try to reduce binge-eating episodes in adults with binge-eating disorder.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06858774

• Same-day gonorrhea and chlamydia testing for young people

  This project will test whether point-of-care gonorrhea and chlamydia testing helps improve HIV testing and same-day PrEP counseling and prescriptions for 16–24-year-olds in pediatric clinics.

  Recruiting Icahn School of Medicine at Mount Sinai · Philadelphia, Pennsylvania · NCT06844045

• Talquetamab treatment for elderly patients with early relapse multiple myeloma

  This study is testing if a new treatment called Talquetamab can help older patients with early relapse multiple myeloma who can't tolerate stronger therapies feel better and have a safer option.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06827860

• Wellness program to improve quality of life in NMOSD patients

  This study is testing a wellness program to see if it can improve the quality of life for people with Neuromyelitis Optica Spectrum Disorder (NMOSD).

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06780709

• Training to improve emotion regulation in people with Borderline Personality Disorder

  This study is testing a new training program to help people with Borderline Personality Disorder learn better ways to manage their emotions.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06772831

• Building a program to enhance community resilience and well-being

  This study is testing a program that offers workshops to help Community Health Workers in New York City feel less stressed and more resilient over four years.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06771167

• Monitoring brain activity in ICU patients with sedation and delirium

  This study is testing a new brain monitoring device to see if it can help doctors better understand sedation and delirium in patients who are intubated and sedated in the ICU.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06718764

• Evaluating neck muscle measurements as indicators of frailty in patients having head and neck surgery

  This study is testing if the size of neck muscles can help predict frailty in patients having non-cancer head and neck surgery.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06704256

• Using chlorhexidine to reduce infections after bladder cancer surgery

  This study is testing if using chlorhexidine during and after bladder cancer surgery can help reduce urinary tract infections for patients recovering from the procedure.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06689176

• Helping people get on the kidney transplant waitlist using community health workers and provider training.

  This project tests whether giving patients support from community health workers plus training for their kidney providers helps adults with advanced kidney failure at participating New York centers get on the transplant waitlist compared with usual care.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York and 2 other locations · NCT06655857

• Using the Sana Device to Reduce Chronic Pain from Lyme Disease

  This study is testing if the Sana Pain Reliever device can help people with chronic pain from Lyme disease feel better.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06655844

• IRRAflow continuous irrigation to clear blood and infection inside the head

  This trial tests whether the IRRAflow system, which continuously irrigates and drains the brain, clears intracranial blood and treats ventriculitis or abscess better than standard external ventricular drains in adults.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06649097

• Digital therapy for chronic back pain

  This study is testing a new digital therapy for chronic back pain to see if it works better than regular treatments for helping people feel less pain.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06641102

• Treatment for locally advanced triple negative breast cancer using a combination of drugs

  This study is testing a new combination of drugs to see if it can safely help people with locally advanced triple negative breast cancer feel better and improve their chances of survival.

  Recruiting Early Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06637306

• Home-based care coaching for managing COPD

  This study is testing a new home-based coaching program to help people with COPD manage their symptoms better and improve their overall health, especially for those from low-income and minoritized backgrounds.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06634810

• A program to support couples dealing with dementia

  This study is testing a new program called Resilient Together for Dementia to see if it can help couples cope better with the emotional challenges of dementia.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06619327

• Improving asthma symptom awareness in older adults

  This study is trying to help older adults with asthma better recognize their breathing problems so they can manage their condition more effectively.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York and 1 other locations · NCT06612294

• Psilocybin combined with pimavanserin for treating major depression

  This study is testing whether combining psilocybin with a medication called pimavanserin can help people with major depression feel better compared to using psilocybin alone.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06592833

• Evaluating pulse oximeter accuracy in children with congenital heart disease

  This study is testing how accurate pulse oximeters are for children with congenital heart disease, especially looking at how skin color might affect their readings before surgery.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06575270

• Comparing ketamine-assisted psychotherapy to ketamine alone for treating depression

  This study is testing whether combining ketamine with therapy can help adults with depression feel better compared to just using ketamine alone.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06559826

• Using low-dose Methotrexate for treating blood cancers

  This study is testing if adding low-dose Methotrexate to the treatment of blood cancers like Polycythemia Vera and Myelofibrosis can help reduce symptoms and improve spleen size for patients.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06541249

• Behavioral therapy to help manage Crohn's disease symptoms

  This study is testing whether a combination of behavioral therapy and support programs can help adults with active Crohn's disease feel better both mentally and physically while they start a new medication.

  Recruiting at 2 sites Icahn School of Medicine at Mount Sinai · New York, New York and 1 other locations · NCT06512597

• Testing antiviral medications for Long Covid

  This study is testing if two HIV antiviral medications can help adults with Long Covid feel better after having symptoms for at least six months.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06511063

• Using Lumbrokinase to treat Long Covid, Lyme Disease, and Chronic Fatigue Syndrome

  This study is testing if a treatment called Lumbrokinase can help adults with Long Covid, Lyme Disease, and Chronic Fatigue Syndrome feel better and improve their quality of life.

  Recruiting Phase 1/2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06511050

• Preventing coronary artery disease in young adults

  This study is testing if closely managing heart health in young adults aged 30-50 can slow down the buildup of artery plaque compared to regular care.

  Recruiting Phase 3 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06494501

• Improving support for Black and Latina women with metastatic breast cancer

  This study is testing a new support program for Black and Latina women with metastatic breast cancer to see if it helps them feel better and access more resources compared to standard care.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06405828

• Virtual-reality self-hypnosis for HIV-related chronic pain

  This trial will try a virtual-reality self-hypnosis program to see if it reduces chronic pain in adults living with HIV.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06398847

• Using ritlecitinib to treat keloids and patients undergoing keloid surgery

  This study is testing if a new medication called ritlecitinib can help treat keloids in people who have them or are having surgery to remove them.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06373458

• Using Hiltonol® to treat prostate cancer patients on active surveillance

  This study is testing if adding Hiltonol® injections to the usual care can help prostate cancer patients who are being closely monitored feel better and stay healthy.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06343077

• Effects of a high fructose diet on gut health and metabolism

  This study is testing how eating a high fructose diet affects gut health and metabolism in people who may struggle to digest fructose.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06329544

• Meaning-Centered Psychotherapy for Caregivers of Cancer Patients

  This study is testing if a special type of therapy called Meaning-Centered Psychotherapy can help caregivers of cancer patients feel less stressed and find more meaning in their lives compared to regular support therapy.

  Recruiting at 8 sites Icahn School of Medicine at Mount Sinai · Miami, Florida and 7 other locations · NCT06307535

• Palliative care for patients with advanced heart failure or cancer

  This study is testing a new palliative care program for people with advanced heart failure or cancer to see if it can improve their quality of life and reduce hospital visits compared to standard care.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06228209

• Using pacritinib with azacitidine for treating chronic myelomonocytic leukemia

  This study is testing if a new combination of two medications, pacritinib and azacitidine, can help people with chronic myelomonocytic leukemia feel better and improve their treatment outcomes.

  Recruiting Phase 1/2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06159491

• Evaluating a 3 oz water protocol for patients with tracheostomies

  This study is testing a new 3 oz water swallowing test for patients with tracheostomies to see if it can better identify those at risk of choking compared to standard swallow tests.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06120790

• Combination treatment for early-stage lung cancer

  This study is testing a combination of two medications, dupilumab and cemiplimab, to see if they can help people with early-stage lung cancer before surgery.

  Recruiting Phase 1/2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06088771

• Study on the effects of antipsychotic medications during pregnancy on mothers and infants

  This study looks at how taking antipsychotic medications during pregnancy affects both mothers with severe mental illness and the development of their babies.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06049953

• Combining Sacituzumab Govitecan with Cisplatin for Ovarian and Endometrial Cancer

  This study is testing a new combination of two drugs, sacituzumab govitecan and cisplatin, to see if it can effectively treat people with recurrent ovarian and endometrial cancers that respond to platinum-based treatments.

  Recruiting Phase 1/2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06040970

• Exploring the impact of microplastics on pregnant women with Crohn's disease

  This study is trying to see how microplastics and toxins in the environment affect gut health in pregnant women with Crohn's disease and their babies.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06001450

• Understanding how eating affects control in bulimia nervosa

  This study is trying to see how eating affects decision-making and control in people with bulimia nervosa by using brain scans and mobile assessments.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05995496

• Understanding brain lesions in multiple sclerosis and related disorders

  This study looks at how brain lesions develop in people with multiple sclerosis and similar conditions over time to better understand their effects and progression.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05982925

• Using a new catheter system to treat intraventricular hemorrhage

  This study is testing a new catheter system to see if it can safely and effectively drain fluid in the brains of patients with intraventricular hemorrhage, compared to standard catheters.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05970549

• Telehealth Cognitive Behavioral Therapy for youth at risk for psychosis

  This study is testing if online therapy can help young people aged 14-25 who are at risk for psychosis feel better and stay connected with their treatment.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05968560

• Implementing an online emotion regulation program for traumatic brain injury

  This study tests which training method helps clinicians better deliver an online program to help people with traumatic brain injury manage their emotions.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05933629

• Using ephedrine to improve fetal heart monitoring during labor

  This study tests if giving ephedrine to women in labor who are using spinal-epidural anesthesia can help improve fetal heart monitoring and reduce low blood pressure.

  Recruiting Phase 4 Icahn School of Medicine at Mount Sinai · New York, New York · NCT05873218

• Using Dupilumab to treat children with Alopecia Areata

  This study is testing if Dupilumab can help children and teens with moderate to severe Alopecia Areata grow their hair back.

  Recruiting at 5 sites Phase 2 Icahn School of Medicine at Mount Sinai · Irvine, California and 4 other locations · NCT05866562

• Using Reparixin to treat patients with Myelofibrosis

  This study is testing if a new medication called Reparixin can help people with myelofibrosis who haven't had success with other treatments.

  Recruiting at 9 sites Phase 2 Icahn School of Medicine at Mount Sinai · Tampa, Florida and 8 other locations · NCT05835466

• Using a nerve block to manage pain after heart surgery

  This study tests if a nerve block can help heart surgery patients feel less pain and use fewer painkillers after their operation.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05833048

• Fecal microbiota transplant for chronic pouchitis treatment

  This study is testing whether a fecal microbiota transplant from healthy donors can help people with chronic pouchitis feel better when other treatments haven't worked.

  Recruiting Early Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York · NCT05829109

• Deep brain stimulation for treatment-resistant depression

  This study is testing if deep brain stimulation can help people aged 25-70 with severe depression who haven't found relief from other treatments.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05773755

• Comparing two therapies for adolescents with anorexia nervosa

  This study is testing which of two therapies works better for teenagers with anorexia nervosa to help them gain weight and feel better over time.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05763849

• Assessing the impact of lighting on multiple myeloma patients undergoing stem cell transplantation

  This study is testing if better lighting in hospital rooms can help multiple myeloma patients feel better and recover more effectively during their stem cell transplant.

  Recruiting at 2 sites Icahn School of Medicine at Mount Sinai · New York, New York and 1 other locations · NCT05737732

• Vagal nerve stimulation for improving recovery after stroke

  This study is testing if vagal nerve stimulation can help people recovering from a stroke feel better and improve their recovery process.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05694663

• Investigating how stress affects impulsivity and alcohol use in African Americans using fMRI

  This study tests how stress affects impulsivity and drinking habits in African Americans using brain scans to see if stereotype threat plays a role.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05675332

• How gut immune tissue responds to HIV cure treatments

  This trial will test whether HIV cure–intent therapies change immune cells in the gut and lower tissue-associated HIV in people living with HIV.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05652088

• Imaging for coronary microvascular dysfunction in patients with angina

  This study is testing a new way to use heart imaging to help people with chest pain and non-blocked arteries feel better and improve their quality of life.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05634031

• Neurofeedback treatment for women with bulimia nervosa

  This study tests if a new brain training method can help women with bulimia nervosa improve their control over eating and reduce their symptoms.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05614024

• Pembrolizumab treatment for advanced non-small cell lung cancer in patients with poor performance status

  This study is testing if pembrolizumab can improve the quality of life for patients with advanced non-small cell lung cancer who can't receive standard treatments because they are not feeling well enough.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT05589818

• Peer coaching to support teens with eating disorders

  This trial will test whether adding 12 weeks of phone-based coaching for either parents or patients alongside usual therapy helps parents feel less emotionally taxed and helps teens build recovery skills.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05562258

• Non-invasive vagus nerve stimulation for treating low weight eating disorders

  This study is testing whether a new type of nerve stimulation before meals can help teenagers with anorexia nervosa feel more satisfied with their meals and eat more without feeling too full.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05554172

• Treatment for moderate to severe alopecia areata using dupilumab

  This study is testing if a medication called dupilumab can help people with moderate to severe alopecia areata, which causes significant hair loss, to regrow their hair.

  Recruiting at 3 sites Phase 2 Icahn School of Medicine at Mount Sinai · Irvine, California and 2 other locations · NCT05551793

• Investigating vancomycin's effects on multiple sclerosis

  This study is testing if the antibiotic vancomycin can change gut bacteria and help improve symptoms in people who have just been diagnosed with multiple sclerosis.

  Recruiting Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York · NCT05539729

• Using ultrasound with special cranioplasty to monitor bleeding after brain surgery

  This study is testing if using ultrasound with a special type of skull implant can help doctors quickly find and measure bleeding after brain surgery for patients with brain hemorrhages.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05538286

• Using cannabinoids to reduce inflammation and pain in sickle cell disease

  This study is testing if a cannabinoid called dronabinol can help adults with sickle cell disease feel less pain and improve their quality of life.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT05519111

• Reducing the Time to Start Treatment for First Episode Psychosis through Screenings and Clearer Information

  This study tests whether a systematic screening approach plus a clear communication model (ComPsych) can shorten the time from onset to specialty care for people at high risk or experiencing first episode psychosis.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05509998

• Identifying genes that affect Acute Intermittent Porphyria

  This study is trying to find out which genes might make people more likely to have attacks of Acute Intermittent Porphyria or help protect them from it, and it's for anyone aged 12 and older who has symptoms or is related to someone with the condition.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05502133

• Using diphencyprone with immune checkpoint inhibitors to treat skin cancer spread

  This study is testing if a topical treatment called diphencyprone can boost the effectiveness of immune therapies in helping people with skin cancer that has spread.

  Recruiting Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York · NCT05481658

• Using antibiotics and pembrolizumab after chemotherapy for pancreatic cancer treatment

  This study is testing whether adding antibiotics and pembrolizumab after chemotherapy can help boost the immune system and improve treatment outcomes for patients with pancreatic cancer that can be surgically removed.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT05462496

• New treatment approach for Mal de Débarquement Syndrome using VR technology

  This study is testing whether virtual reality goggles can help people with Mal de Débarquement Syndrome feel better when used with regular therapy.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05460520

• Robotic surgery for HPV-related throat cancer

  This study is testing if robotic surgery can be a safe and effective treatment for patients with HPV-related throat cancer who have low levels of cancer markers after surgery, to see if it works as well as traditional treatments without the harsh side effects.

  Recruiting at 2 sites Phase 2 Icahn School of Medicine at Mount Sinai · Paramus, New Jersey and 1 other locations · NCT05419089

• Understanding sexual side effects after radiotherapy in female cancer patients

  This study is trying to understand how radiotherapy and other cancer treatments affect sexual health in women with cancer to help improve their quality of life.

  Recruiting at 3 sites Icahn School of Medicine at Mount Sinai · Atlanta, Georgia and 2 other locations · NCT05394428

• Using Transcutaneous Spinal Cord Stimulation to stabilize blood pressure after spinal cord injury

  This study is testing whether a new method using Transcutaneous Spinal Cord Stimulation can help stabilize blood pressure in people with recent spinal cord injuries during their rehab.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05305118

• Effects of music therapy on breathing and brain oxygen levels in premature infants

  This study tests if music therapy with ocean sounds can help improve breathing and oxygen levels in premature babies.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05223192

• Screening women with a history of HPV for anal cancer precursors

  This study is testing different screening methods for anal cancer precursors in women who have had HPV and certain other cancers to see which ones work best.

  Recruiting at 3 sites Icahn School of Medicine at Mount Sinai · New York, New York and 2 other locations · NCT05217940

• Metabolic Diet for preventing relapse in anorexia nervosa

  This study tests if a special diet can help women who have recovered from anorexia nervosa stay healthy and prevent relapse.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05197309

• Investigating how environmental factors affect thyroid cancer

  This study is trying to see how different environmental factors might influence the development and progression of thyroid cancer in adults who have been diagnosed with it.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05172921

• Personalized deep brain stimulation of the anterior limb of the internal capsule for OCD

  This study tests whether tailoring deep brain stimulation to each person's specific ALIC brain connections can help adults with severe, treatment‑resistant OCD.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05160129

• Combining Abemaciclib and Bicalutamide for Advanced Breast Cancer

  This study is testing if combining two drugs, Abemaciclib and Bicalutamide, can help people with advanced breast cancer feel better and live longer.

  Recruiting at 3 sites Phase 1/2 Icahn School of Medicine at Mount Sinai · New York, New York and 2 other locations · NCT05095207

• Light therapy for patients with Alzheimer's disease

  This study is testing if special blue light therapy can help improve sleep and thinking skills in people with mild Alzheimer's disease and mild cognitive impairment.

  Recruiting at 2 sites Icahn School of Medicine at Mount Sinai · Menands, New York and 1 other locations · NCT05016219

• Leflunomide treatment for patients with advanced solid tumors lacking PTEN expression

  This study is testing if leflunomide can be a safe and effective treatment for people with advanced solid tumors that don't have the PTEN protein.

  Recruiting Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York · NCT04997993

• Biorepository for patients receiving biologic therapy at Mount Sinai

  This study is collecting health information from patients receiving biologic therapy at Mount Sinai to help improve treatments for various immune-related diseases.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT04784364

Showing recruiting studies first, then the newest. Describe your situation to find the ones that fit you.

NIH-funded research (newest 40 of 1523)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Improving Breast Cancer Guideline Adherence in Nigeria

  Aimed at helping doctors in Nigeria follow international guideline-based breast cancer care to improve outcomes for women with breast cancer.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11625517

• Genetically Validated PCOS Subtypes for Better Diagnosis and Risk Stratification

  Aimed at women with polycystic ovary syndrome (PCOS), this project uses genetic data and patient characteristics to define distinct PCOS subtypes and improve how we diagnose and estimate risk.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11623556

• Closed-loop control of interneuron timing to influence seizures and memory in epilepsy

  A study tests a brain-quieting system that uses light to precisely time certain brain cells in epilepsy-prone mice to see if this can lessen seizures and improve memory.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11617814

• Understanding why some brain regions and cells accumulate tau in Alzheimer’s and related diseases

  Researchers are studying why certain brain areas and neuron types accumulate tau protein in Alzheimer’s and related conditions, and how this leads to brain changes and symptoms.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11617738

• Improving blood flow after stroke by breaking down NETs

  Aims to see if breaking down neutrophil extracellular traps (NETs) after an ischemic stroke can improve blood flow and reduce brain injury in patients.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11606640

• Aging and brain injury connection: learning how late-life TBI relates to Alzheimer’s and related dementias

  This grant looks at whether traumatic brain injuries in people 65 and older are linked to Alzheimer’s disease and related dementias, using a large, harmonized set of long-term aging studies.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11606525

• Cellular aging in Alzheimer's disease: finding senescent cells and their patterns

  Researchers will study whether aging-like cells called senescent cells appear in the brains of people with Alzheimer's disease and what their patterns mean for disease progression.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11605840

• A reusable, low-cost forehead EEG patch to track sleep patterns linked to memory and dementia

  A small, comfortable EEG patch for older adults lets people sleep at home for several nights while researchers collect brainwave data related to aging and Alzheimer’s disease.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11603222

• Understanding how Alzheimer's progresses over time using sparse brain scans and blood markers

  This grant aims to map the progression timeline of Alzheimer's disease using limited, real-world brain imaging and blood data to identify biomarkers and critical treatment windows.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11603148

• Functional Connectivity-Guided TMS for Alcohol Use Disorder

  A new approach uses targeted brain stimulation to help people with alcohol use disorder stay abstinent longer by focusing treatment on specific brain circuits.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11601597

• Improving WTC responder mental health with personalized sleep treatment for COMISA

  Aimed at helping World Trade Center responders who have both insomnia and sleep apnea feel better by using a tailored combination of sleep therapies.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11578881

• WTC Dust and Thyroid Cancer Progression in Human Organoids

  This grant tests how World Trade Center dust might influence thyroid cancer progression using human thyroid organoids to model real-life exposure.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11578742

• Early life air pollution and kids’ heart health: how metals in the air affect children from birth to age 12

  This grant studies how pollution from cooking fires and wood smoke in early life may shape a child’s heart health through age 12.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11554603

• Metal mixtures in early life impacting teen risk-taking

  A long-term study follows people from pregnancy through adolescence to see how metal exposures in early life relate to how teens take risks.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11554572

• Long-term study of metal exposure and teen risk-taking

  A long-term study following people from birth into late adolescence to understand how early metal exposures relate to how teens think about and take risks.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11554477

• Stress and air pollution during pregnancy and adolescence health study

  This grant explores how air pollution and stress around birth may influence brain development and contribute to obesity and mood problems in teenagers.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11553888

• Stress and air pollution: how early life exposures shape teen obesity and mood

  Early-life air pollution and stress may influence how the brain develops to control eating and mood, potentially leading to obesity and affective symptoms in adolescence.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11553887

• How social isolation affects aging health in schizophrenia

  This project explores how being socially isolated may speed up health problems as people with schizophrenia age.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11551517

• How Social Isolation Impacts Aging in People with Schizophrenia

  This study looks at how social isolation affects aging and health in people with schizophrenia to see if loneliness and lack of social contact worsen medical problems as they grow older.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11551516

• How social isolation affects aging health in schizophrenia

  A patient-friendly look at how being socially isolated might influence aging and health in people with schizophrenia.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11551515

• The effect of social isolation on aging health in people with schizophrenia

  This study explores how being socially isolated may speed up aging-related health problems in people with schizophrenia.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11551514

• Cognitively-enhanced tDCS to reduce cocaine craving

  A study to test whether real brain stimulation together with learning strategies can lessen craving in people with cocaine use disorder.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11550899

• HERV proteogenomics and HIV latency in the brain

  Researchers are exploring how human endogenous retroviruses interact with HIV hiding in brain cells, with the aim of finding ways to wake and reveal latent HIV so it can be cleared.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11541274

• Computational analysis of facial expression in early psychosis

  Aims to develop computer-based measures of facial expression in people at risk for or with schizophrenia to help track symptoms and guide future trials.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11539126

• Consortium advancing care and prevention of cancers in people with HIV

  A national and international network is testing new cancer treatments and prevention strategies for people living with HIV to help reduce cancer-related illness and death.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11535258

• Consortium to Improve Cancer Care for People with HIV

  A nationwide network conducts clinical trials to find better treatments and prevention strategies for cancers in people living with HIV.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11535257

• Cancer prevention and treatment for people living with HIV through coordinated trials

  A large, ongoing program tests new cancer treatments and prevention strategies specifically for people living with HIV to reduce cancer burden.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11535256

• Consortium advancing cancer care for people with HIV

  A nationwide and international network tests new cancer treatments and prevention strategies specifically for people living with HIV.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11535255

• Consortium advancing cancer care for people with HIV

  A national collaboration tests new cancer treatments and prevention strategies specifically for people living with HIV to reduce cancer-related illness and death.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11535254

• AIDS-related cancers and HIV care: advancing treatment and prevention

  A networked effort across many sites aims to improve treatment and prevention of cancers in people living with HIV around the world.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11535253

• Consortium advancing cancer care for people with HIV

  A nationwide network tests new cancer treatments and prevention strategies to help people living with HIV reduce their cancer risk and improve outcomes.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11535252

• Consortium advancing cancer prevention and care for people with HIV

  A patient-facing program aims to test new cancer treatments and prevention strategies for people living with HIV, through clinical trials conducted in the U.S. and around the world.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11535251

• Advancing Cancer Care for People with HIV

  A national effort tests new cancer treatments and prevention ideas to help people living with HIV reduce their cancer risk and improve outcomes.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11535250

• AIDSMALIGNANCY CONSORTIUM: advancing care and prevention for people with HIV-related cancers

  A long-running NIH program tests new cancer treatments and prevention strategies for people living with HIV to reduce cancer in this population.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11535249

• SARS-CoV adaptations through a Systems Biology Lens (SYBIL) in humans and animal models

  A team at Mount Sinai is studying how SARS-CoV-2 affects the body by mapping host-virus networks and blood biomarkers to identify new targets for therapy.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11533180

• Understanding how exercise changes the body at the molecular level

  A large study is looking at how starting and maintaining exercise changes gene activity and related biology in adults, using blood, muscle, and fat samples.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11532086

• Antipsychotic use during pregnancy and infant development

  This project follows pregnant women with severe mental illness to see how taking antipsychotics during pregnancy affects maternal health, baby health at birth, and child development in the first 6 months.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11530214

• Chemistry and structure studies of energy balance in cancer and metabolic diseases

  Scientists are studying how energy and protein balance affect diseases like Alzheimer’s and cancer using chemistry and structural biology.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11529336

• Mapping how Ig-fold membrane proteins talk to their partners with nanobody tools

  This grant supports building a high-precision tool to map how immune-related membrane proteins communicate with their partners in living cells.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11529125

• All of Us New York Consortium: Building a National Health Data Resource for Precision Medicine

  A Mount Sinai-led effort to maintain and enrich the All of Us data resource in New York to help researchers study how genetics, health records, and other information can improve personalized care for patients.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11526616

Quick answers

How many clinical trials run by Icahn School of Medicine at Mount Sinai are recruiting right now?

167, as of November 12, 2026. 3 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (166 trials), United Kingdom (2 trials), Brazil (1 trial), Canada (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 29, Phase 1/2: 9, Phase 1: 9, Phase 3: 7. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →