NIH-funded research R01 grant

Stress and air pollution during pregnancy and adolescence health study

Official title: Stress-Air Pollution Interactions and Adolescent Neurobehavior

Funded at Icahn School of Medicine at Mount Sinai · NIH-11553888 · Data updated 2026-11-12

This grant explores how air pollution and stress around birth may influence brain development and contribute to obesity and mood problems in teenagers.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai
NIH-funded
Lab location1 site (New York, United States)
Project startJanuary 15, 2007
Project endMay 31, 2028
Funding year2026
Award (this year)$69,730
NIH project number3R01ES013744-19S2
Project IDNIH-11553888 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents and young people in the PROGRESS cohort, especially those with prior exposure to perinatal pollution and stress.

Less likely to help

Children without long-term follow-up data or those not in the PROGRESS cohort may not directly benefit.

What this research studies

This project follows children in a long-term cohort to see if early exposure to air pollution and stress affects learning, eating habits, and weight gain over the first two decades of life. It uses data gathered from birth onward in a Mexico City cohort to link environmental exposures with later obesity and mental health outcomes. The team will apply new statistical methods to identify when exposure matters most and how brain development, self-control, and mood are connected to weight gain.

Why it matters

Potential benefit: If successful, it could clarify when and how environmental factors shape obesity and mental health, guiding prevention strategies for at-risk youth.

How similar studies have gone: Previous studies have linked early exposures to later obesity and mood changes, but this long-term longitudinal approach is novel.

Where this research is happening

  • Icahn School of Medicine at Mount Sinai
    New York, United States
    Active

Researchers

  • Principal investigator: Wright, Robert O — Icahn School of Medicine at Mount Sinai
  • Study coordinator: Wright, Robert O

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.