Understanding brain lesions in multiple sclerosis and related disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the natural history and immunologic mechanisms of central nervous system lesions, particularly in the cerebral cortex, in patients with multiple sclerosis and other demyelinating autoimmune diseases. Participants, including healthy controls, will undergo a series of evaluations including MRI scans, blood tests, and cerebrospinal fluid analysis at baseline and follow-ups over six years. The study will also monitor new lesion formation and compare different MRI techniques. The goal is to gain insights into the clinical implications of these lesions and their progression over time.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years old
* able to provide consent in English
* able to undergo MRI

Exclusion Criteria:

* contraindication to MRI
* pregnancy

Where it's running

• Mount Sinai Hospital
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Erin S Beck, MD, PhD — Icahn School of Medicine at Mount Sinai
• Study coordinator: Erin S Beck, MD, PhD
• Email: erin.beck@mssm.edu
• Phone: 212-241-2474

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.