Meaning-Centered Psychotherapy for Caregivers of Cancer Patients

Meaning-Centered Psychotherapy to Meet Palliative Care Needs of Cancer Caregivers

NA · Icahn School of Medicine at Mount Sinai · NCT06307535

This study is testing if a special type of therapy called Meaning-Centered Psychotherapy can help caregivers of cancer patients feel less stressed and find more meaning in their lives compared to regular support therapy.

Quick facts

PhaseNA
Study typeInterventional
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorIcahn School of Medicine at Mount Sinai (other)
Locations8 sites (Miami, Florida and 7 other locations)
Trial IDNCT06307535 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of Meaning-Centered Psychotherapy for caregivers of patients with Stage III or IV solid tumor cancer. Participants will complete questionnaires assessing their sense of meaning, spiritual well-being, and levels of distress before and after undergoing either Meaning-Centered Psychotherapy or standard Supportive Psychotherapy. The study aims to determine the impact of these interventions on caregiver burden and stress over a period of time. Participants will be monitored through follow-up questionnaires at 2 weeks, 6 months, and 12 months post-treatment.

Who should consider this trial

Good fit: Ideal candidates are caregivers aged 18 or older who are currently caring for patients with advanced solid tumor cancer and experiencing distress related to their caregiving role.

Not a fit: Patients who are not currently caregivers or those engaged in regular individual psychotherapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly reduce caregiver burden and improve the mental well-being of caregivers for cancer patients.

How similar studies have performed: Other studies have shown promising results with psychotherapy approaches for caregivers, indicating potential success for this intervention.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 or over;
* As per self-report, a current caregiver to a patient with Stage III or IV solid tumor cancer currently receiving medical care of any kind (e.g., curative, palliative);
* Experiences distress as evidenced by a score of 4 or greater on the Distress Thermometer (DT) and an indication that this distress is associated with caregiving;
* As per self-report, can read and understand English;
* As per self-report, residing in New York, New Jersey, or Florida, or have the ability to complete sessions while complying with current telehealth regulations.

Exclusion Criteria:

* Participant does not have a reasonable understanding of the study activities by the judgment of the consenting professional;
* Engagement in regular individual psychotherapeutic support that the participant is unable or unwilling to put on hold for the course of treatment.

Where this trial is running

Miami, Florida and 7 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Caregiver Burden, Caregiver Burnout, Caregiver Stress Syndrome, Caregiver, Meaning-Centered Psychotherapy, 23-376

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.