Positioning strategies to treat proximal ureteral stones

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial compares two patient positioning strategies during flexible ureteroscopy for proximal ureteral stones: reverse Trendelenburg versus T-tilt. The primary outcome is operative time, reflecting procedural efficiency. Enrolling 54 adults with stones >1 cm or multiple stones at Mount Sinai West, the study aims to see if changing gravity-related stone behavior can reduce retropulsion and unnecessary instrument changes. The trial addresses a gap in optimizing intraoperative technique for proximal ureteral stones with minimal added cost or complexity.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Adults aged 18 years and older.
* Diagnosed with kidney stones and scheduled for fURS.
* Stone burden \> 1 cm and/or multiple stones will be eligible.
* Able and willing to provide informed consent.

Exclusion criteria:

* Pregnant persons as determined by pre-operative urine pregnancy test (standard of care at the institution)
* Untreated UTI
* Patients with urinary anomalies (e.g., urinary diversion, ureteral reconstruction, horseshoe kidney)
* Single stone \< 1 cm

Where it's running

• Mount Sinai West
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Mantu Gupta, MD — Icahn School of Medicine at Mount Sinai
• Study coordinator: Mantu Gupta, MD
• Email: mantu.gupta@mountsinai.org
• Phone: 212-241-1272

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Initial drainage method for a solitary kidney stone causing kidney failure

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.