Using ephedrine to improve fetal heart monitoring during labor

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of prophylactic ephedrine on fetal heart rate tracings and uterine contractions in women receiving combined spinal-epidural anesthesia for labor analgesia. The research aims to determine if administering ephedrine can reduce the incidence of category II fetal heart rate tracings and low blood pressure, which are known side effects of this anesthesia method. Participants will be randomly assigned to receive either ephedrine or a normal saline placebo. The study is significant as it explores an investigational use of ephedrine in this context, which has not been routinely practiced.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women aged 18-55 years
* Requesting labor analgesia
* Able to provide informed written consent
* Category 1 fetal tracing prior to placement of neuraxial anesthesia

Exclusion Criteria:

* Refusal of neuraxial anesthesia
* History of hypertension
* Suspected pre-eclampsia
* Category 2 or 3 fetal tracing prior to placement of neuraxial anesthesia

Where it's running

• Icahn School of Medicine at Mount SInai
  New York, New York, United States Recruiting

Study contacts

• Study coordinator: Daniel Katz, MD
• Email: daniel.katz@mountsinai.org
• Phone: 212-241-7475

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.