MIND diet for adults with multiple sclerosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, stratified early phase II trial assigns adults with MS to either a one-year MIND dietary intervention with dietitian-led education and virtual support groups, or to a control arm that continues their usual diet and receives MS-related education unrelated to diet. Participants complete baseline, 6-month, and 12-month in-person visits with functional and cognitive testing, provide blood and stool samples, and complete online questionnaires. The intervention arm receives intensive virtual small-group meetings weekly for the first month and then monthly through month 12 to support MIND diet adherence. Randomization is stratified by MS phenotype and treatment type to balance groups.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Ages 18-70 years, inclusive
* MS diagnosis, on any treatment (including no treatment)
* MIND diet score of ≤9 at baseline

Exclusion Criteria:

* Diagnosis of an additional neurodegenerative disease (e.g. Alzheimer's) or other serious neurological condition (e.g. stroke)
* Current serious medical condition that could impact the ability to participate or influence study results (e.g. cancer, HIV)
* Pregnancy/planning during study period

Where it's running

• Mount Sinai Hospital
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Ilana B Katz Sand, MD — Icahn School of Medicine at Mount Sinai
• Study coordinator: Claire E Wigley, Bsc, BSPH
• Email: claire.wigley@mssm.edu
• Phone: (212) 241-3759

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.