Wellness program to improve quality of life in NMOSD patients

Impact of a Structured Wellness Behavioral Intervention on Quality of Life in NMOSD

Not applicable Interventional Icahn School of Medicine at Mount Sinai · NCT06780709

This study is testing a wellness program to see if it can improve the quality of life for people with Neuromyelitis Optica Spectrum Disorder (NMOSD).

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years and up
SexAll
SponsorIcahn School of Medicine at Mount Sinai Academic / other
Locations1 site (New York, New York)
Trial IDNCT06780709 on ClinicalTrials.gov

What this trial studies

This project investigates the effectiveness of a structured wellness program designed to enhance the quality of life for individuals with Neuromyelitis Optica Spectrum Disorder (NMOSD). The pilot study will involve 20 participants who will be randomly assigned to either an immediate intervention group or a control group that starts the program after six months. The wellness intervention includes services from physical therapists, dietitians, social workers, and cognitive therapists, with assessments conducted at baseline, 12 weeks, and 6 months to evaluate outcomes. The primary focus is on measuring quality of life using the MS-Quality of Life -54 scale.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older diagnosed with NMOSD who can participate in the study evaluations.

Not a fit: Patients under 18, those unable to provide consent, or those with recent relapses or medical restrictions on physical activity may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly enhance the quality of life for patients living with NMOSD.

How similar studies have performed: While similar wellness interventions have shown promise in other conditions, this specific approach for NMOSD is novel and untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria:

* Adults (age ≥18) with NMOSD diagnosed with 2015 NMOSD clinical criteria.
* All EDSS scores will be considered in order to make the intervention accessible to all patients regardless of disability.
* All patients regardless of treatment type will be considered.

Exclusion criteria:

* Age\<18
* Inability to voluntarily provide consent for study participation
* Inability to participate in study evaluation and/or endpoint measures, or participation in another concurrent randomized controlled trial or wellness based intervention.
* Any patients with a relapse within 30 days of randomization or any patients with medical restrictions on physical activity will be excluded.
* Any patients who begin stimulants and/or dalfampridine between enrollment and randomization will be excluded.

Where this trial is running

New York, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Neuromyelitis Optica Spectrum DisorderNMOSDWellnessDietPhysical TherapySocial WorkComprehensive
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.