PRP injection for female sexual function

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, single-blinded study compares autologous platelet-rich plasma (PRP) injections to sterile saline injections in women with sexual dysfunction. Sixty participants with FSFI scores 26.5 or lower are assigned 1:1 to PRP or saline and followed for 6 months. Blood is drawn from all participants to maintain blinding, with PRP processed for the treatment arm and discarded in the control arm. Injections are delivered just under the vaginal epithelium, and outcomes include sexual function and related symptoms assessed at baseline, 6 weeks, and 6 months, with some visits possible remotely.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female, 18 years of age or older, presenting with sexual dysfunction
* FSFI total score ≤ 26.5
* English speaking and literate

Exclusion Criteria:

* Unwilling or unable to provide informed consent
* Pregnant or less than 12 weeks postpartum
* Known history of bleeding disorder

Where it's running

• The Mount Sinai Hospital
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Charles Ascher-Walsh, MD — Icahn School of Medicine at Mount Sinai
• Study coordinator: Yara Sifri, MD
• Email: vaginalprp@gmail.com
• Phone: 978-273-1786

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.