NIH-funded research R01 grant

How social isolation affects aging health in schizophrenia

Official title: The impact of social isolation on aging health in schizophrenia

Funded at Icahn School of Medicine at Mount Sinai · NIH-11551517 · Data updated 2026-11-12

This project explores how being socially isolated may speed up health problems as people with schizophrenia age.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 15, 2022
Project endMay 31, 2027
Funding year2026
Award (this year)$21,280
NIH project number3R01MH128971-05S4
Project IDNIH-11551517 on NIH RePORTER

Who could benefit from this research

Could help

Adults diagnosed with schizophrenia or related disorders who experience social isolation and are able to participate in long-term follow-up.

Less likely to help

Individuals without social isolation or not engaged in long-term follow-up may see limited direct benefit.

What this research studies

People with schizophrenia often face a shorter life expectancy, partly due to accelerated aging. This study tests how social isolation might worsen aging-related health issues in this population, using data from diverse sites in the US and Europe. By combining deep phenotyping and long-term follow-up, researchers aim to understand the links between isolation, lifestyle, and medical conditions to inform care strategies. The work involves collaboration across clinics and research centers to track health outcomes over many years.

Why it matters

Potential benefit: If successful, findings could guide interventions to reduce social isolation and improve aging-related health in schizophrenia.

How similar studies have gone: Previous work shows social factors influence health in aging, but this study integrates international cohorts and deep phenotyping for schizophrenia.

Where this research is happening

  • Icahn School of Medicine at Mount Sinai
    New York, United States
    Active

Researchers

  • Principal investigator: Reichenberg, Abraham — Icahn School of Medicine at Mount Sinai
  • Study coordinator: Reichenberg, Abraham

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.