Personalized Exercise Recommendations for Chronic Pelvic Pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study explores the feasibility of delivering personalized exercise recommendations for chronic pelvic pain disorders using reinforcement learning. Participants receive daily app-based exercise guidance that alternates between generic recommendations and RL-generated, individualized plans across four 2-week phases, allowing within-person comparison. Data from daily pain scores, symptoms, exercise behavior, and app feedback are collected, along with Fitbit activity tracking. The study is remote, spans 9 weeks (with a possible 2-week extension), and aims to determine whether an RL-based approach can be feasibly implemented in a CPPD population.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Self-reported CPPD (e.g., endometriosis, adenomyosis, fibroids, etc.) based on clinician diagnosis
* Aged 18-55 years.
* Ownership of an iOS or Android smartphone.
* Willingness to self-track daily symptoms, exercise activities, and self-management behaviors using a smartphone research app.
* Willingness to wear an activity tracker for the study duration.
* Willingness to follow exercise recommendations from a smartphone research app, provided no adverse symptoms occur.
* Ability to read and write in English sufficient to understand study materials and communications.
* At least intermittently physically active (e.g., ≥30 minutes of walking twice per week).

Exclusion criteria:

* Absolute contraindications to PA (e.g., recent myocardial infarction, complete heart block, acute congestive heart failure, unstable angina, or uncontrolled severe hypertension, BP ≥180/110 mm Hg).
* More than two "Yes" responses on the Physical Activity Readiness Questionnaire (PAR-Q) (16) without physician clearance.
* Major life events expected during the next 10 weeks (e.g., pregnancy, planned surgery, or extended travel likely to interfere with participation).
* Current or planned pregnancy within the next 6 months.
* Having given birth in the past 6 months or currently nursing.
* Inability to wear an activity tracker or use the app for the study duration.
* Complete inactivity (i.e., \<60 minutes of moderate-intensity PA per week).

Where it's running

• Icahn School of Medicine at Mount Sinai
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Ipek Ensari, PhD — Icahn School of Medicine at Mount Sinai
• Study coordinator: Ipek Ensari, PhD
• Email: ipek.ensari@mssm.edu
• Phone: 631-565-1829

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Pelvic Floor Therapy plus Exercise for Endometriosis-Related Pelvic Pain

  This 12-week study tests whether specialized pelvic floor physical therapy plus a structured exercise program helps reduce chronic pelvic pain in women with endometriosis more than a placebo version of pelvic floor therapy plus the same exercise plan.

  Recruiting Hospital de Clinicas de Porto Alegre · Porto Alegre, Rio Grande do Sul · NCT07733583

• Pelvic Floor Function and Endometriosis-Related Pelvic Pain in Women

  This study will look at whether endometriosis-related pelvic pain is linked to pelvic floor muscle strength and related factors in women aged 18–50, comparing them with healthy controls.

  Recruiting University of Pecs · Pécs, Baranya · NCT07713108

• Samphire Guided Care for Wellbeing at Work

  This study tests a 12-week digital program with at-home neuromodulation to see if it helps women with menstrual or perimenopausal symptoms feel better at work and in daily life.

  Recruiting Samphire Group, Inc. · San Francisco, California · NCT07679074

• Educational podcast for people with chronic pelvic pain and endometriosis

  This project will test whether giving adults with chronic pelvic pain or endometriosis access to an educational podcast along with their usual care helps improve quality of life, reduce stigma, or increase satisfaction with care compared with usual care alone.

  Recruiting Vanderbilt University Medical Center · Nashville, Tennessee · NCT07568834

• Electroacupuncture for pelvic pain in women with suspected endometriosis

  This study tests whether a series of electroacupuncture sessions can reduce pelvic pain in women awaiting diagnostic laparoscopy for suspected endometriosis.

  Recruiting St. Olavs Hospital · Trondheim · NCT07305025

• Franco-European Institute of Endometriosis long-term outcomes cohort

  This cohort will follow women with confirmed pelvic endometriosis to see if different medical and surgical treatments lead to better long-term symptoms, quality of life, recurrence rates, and fertility outcomes.

  Recruiting Clinique Tivoli Ducos · Bordeaux · NCT07243587

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.