Metabolic Diet for preventing relapse in anorexia nervosa

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study evaluates the safety, tolerability, and efficacy of a Metabolic Diet designed for women with anorexia nervosa who have recently achieved a healthy weight. The study will enroll 20 participants, including 10 weight-restored women with anorexia nervosa and 10 matched healthy controls. Participants will meet weekly with a registered dietitian to implement the diet, which focuses on altering macronutrient proportions to stabilize blood glucose levels. The intervention lasts for 8 weeks, during which adherence and metabolic parameters will be monitored.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female
* Age at least 18 and not over 40
* BMI at or above 18.5 kg/m2
* Speaks English
* Medically stable, as cleared by a licensed physician, with vital signs and initial blood draws
* History of DSM-5 diagnosis of Anorexia Nervosa (WR-AN only)
* Weight-restored from underweight BMI (under 18.5 kg/m2) within the past 6 months (WR-AN only)

Exclusion Criteria:

* Current/lifetime diagnosis of DSM-5 psychotic disorders, bipolar disorders
* Active DSM-5 substance use disorders
* On medications that could affect metabolism

  \*Subjects are to be free of any medications that could affect metabolism, as discussed with study physician, for 2 weeks prior to primary study visit for glucose function testing.
* History of suicide attempt within previous 6 months or acute suicide risk
* Significant current medical illness or metabolic conditions, including diabetes mellitus and pregnancy
* Current/lifetime diagnosis of DSM-5 eating disorders (HC only)
* Active DSM-5 depressive disorders (HC only)

Where it's running

• Icahn School of Medicine at Mount Sinai
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Chinara Tate — Icahn School of Medicine at Mount Sinai
• Study coordinator: Chinara Tate
• Email: chinara.tate@mssm.edu
• Phone: (212) 659-8724

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Hormone and metabolic patterns in hypothalamus-like brain cells from people with anorexia nervosa

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• Narrative medicine workshops to support teens and young adults with anorexia nervosa (virtual)

  This program tests whether a six-week series of narrative medicine workshops can help 16–25-year-olds with anorexia nervosa express themselves, reflect, and build resilience.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.