Improving WTC responder mental health with personalized sleep treatment for COMISA

Who could benefit from this research

What this research studies

This project looks at WTC responders with both insomnia and sleep apnea and tests whether a personalized treatment combining CBT for insomnia with PAP therapy improves mental health outcomes. Researchers will classify patients by a sleep endotype called low arousal threshold to customize who gets which therapy and in what sequence. The study builds on existing evidence that better sleep health can reduce anxiety and depression and aims to tailor treatment to individual sleep biology.

Why it matters

Where this research is happening

• Icahn School of Medicine at Mount Sinai
  New York, United States Active

Researchers

• Principal investigator: Tolbert, Thomas Mcduffy — Icahn School of Medicine at Mount Sinai
• Study coordinator: Tolbert, Thomas Mcduffy

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.