Condition

Sedentary Behavior clinical trials and research

• 28Clinical trials
• 24NIH research projects
• 10Countries

Newest Sedentary Behavior clinical trials

All recruiting trials (28)

• Acute Endocrine Responses to Aerobic vs. Anaerobic Exercise in Sedentary Young Women

  This study tests how thyroid hormones and cortisol change after aerobic versus anaerobic exercise in sedentary women aged 18-25.

  Recruiting Inonu University · Karabük, Karabük Province · NCT07823335

• See if short bursts of activity every day improve fitness and health in inactive young adults

  This study tests whether short, frequent bouts of exercise throughout the day can boost activity levels, fitness, and health in adults who aren’t currently active.

  Recruiting University of Wisconsin, River Falls · River Falls, Wisconsin · NCT07718113

• Family Good Health Traditions for Life program

  This program will try a community-tailored, family-based version of the Diabetes Prevention Program to help Black parents with prediabetes and their children lower weight and reduce diabetes risk.

  Recruiting Morehouse School of Medicine · Albany, Georgia · NCT07441655

• Mat Pilates to improve body awareness and activity in sedentary young women

  This program will try mat Pilates for 8 weeks to see if it helps sedentary women aged 18–29 increase body awareness and physical activity.

  Recruiting Necmettin Erbakan University · Konya, Tyrkey · NCT07362277

• Sit Less, Move More program to increase physical activity during pregnancy

  This program will try a Fitbit-based Sit Less, Move More plan to help pregnant women under 12 weeks gestation who do less than 150 minutes of activity per week sit less and move more.

  Recruiting University of Central Florida · Orlando, Florida · NCT07223112

• Home exercise program delivered through a smartphone app to reduce fear of movement and improve fitness after a heart attack

  This will test whether a home exercise program delivered through a digital health app helps sedentary patients three months after a heart attack reduce fear of movement (kinesiophobia) and improve functional capacity.

  Recruiting Riphah International University · Islamabad, Federal · NCT07138911

• Investigating how the timing of high-intensity exercise affects eating and activity behaviors

  This study is testing how exercising at different times of the day affects the eating and activity habits of people who don’t usually exercise.

  Recruiting National Taiwan Normal University · Taipei · NCT06966414

• Breaking up long sitting periods to improve heart health and reduce chemo side effects in adults with lymphoma on R-CHOP or POLA-R-CHP

  This trial will test whether a 12-week program that interrupts long periods of sitting helps newly diagnosed adults with lymphoma receiving R-CHOP or POLA-R-CHP chemotherapy improve heart health and reduce chemotherapy side effects.

  Recruiting Dana-Farber Cancer Institute · Boston, Massachusetts · NCT06923397

• Examining how exercise affects metabolism and energy use

  This study tests how regular running can help overweight adults lose weight and understand how exercise affects their energy use.

  Recruiting Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences · Shenzhen, Guangdong · NCT06923163

• Boosting physical activity with tech, social support, and stress resilience

  This study tests whether adding technology-based tools plus social support and stress-resilience activities helps older adults living alone with subjective cognitive decline become more physically active.

  Recruiting Arizona State University · Phoenix, Arizona · NCT06896825

• Effects of high-volume upper limb training on physical and cognitive health

  This study tests whether doing a lot of upper body exercises can improve both physical fitness and thinking skills in inactive adults aged 18-50.

  Recruiting Tarsus University · Tarsus, Mersi̇n · NCT06754579

• Park-based fitness program for older adults

  This study is testing whether a fitness program in local parks can help older adults aged 50 and up improve their heart health and stay active.

  Recruiting Duke University · Miami, Florida · NCT06604650

• Improving sleep and reducing sedentary behavior in people with Type 2 diabetes

  This study is testing whether a program that includes therapy for sleep issues and support for being more active can help people with Type 2 diabetes sleep better and move more.

  Recruiting University of Leicester · Leicester, Leicestershire · NCT06471634

• Exercise and diet to lower heart and metabolic risk in breast cancer survivors

  This project will test whether a 6-month program of Health Canada–based exercise, with or without a healthy-eating counseling program, helps reduce cardiometabolic risk and improve body composition in postmenopausal women who survived early-stage breast cancer and have overweight.

  Recruiting University of Toronto · Toronto, Ontario · NCT06454864

• Sit Less and Move More — reducing prolonged sitting in older adults

  This program tests whether reducing long periods of sitting can improve heart and metabolic health and physical function in overweight adults aged 65 and older who use a smartphone.

  Recruiting Hong Kong Metropolitan University · Ho Man Tin · NCT06427603

• Effects of changing physical activity levels on health in middle-aged adults

  This study tests how changing physical activity levels—either cutting back or increasing exercise—affects health in middle-aged adults, especially looking at issues like metabolic syndrome and cognitive decline.

  Recruiting University of Nottingham · Nottingham, Notts · NCT06377254

• Intervention for reducing cardiometabolic risk in women through exercise and diet

  This study is testing whether exercise alone, or exercise combined with diet advice, can help pre and postmenopausal women lower their risk of heart and metabolic issues.

  Recruiting University of Toronto · Toronto, Ontario · NCT06345937

• Impact of workplace sedentary behavior interventions on health in emergency responders

  This study is testing if using sit-and-stand desks or exercise bikes can help emergency responders like dispatchers and firefighters reduce sitting time and improve their health.

  Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand · NCT05931406

• Using prescribed physical activity to improve health in people with disabilities

  This study is testing whether a program that prescribes specific physical activities can help children and young people with disabilities, like autism and intellectual disabilities, improve their health and be more active.

  Recruiting Region Skane · Malmö · NCT05867940

• Digital health intervention for pregnant Black teens

  This study is testing a digital health program called Mama Let's Move to see if it can help pregnant Black teens in the Mississippi Delta stay active and improve their health.

  Recruiting University of Mississippi Medical Center · Jackson, Mississippi and 1 other locations · NCT05843903

• Program to improve health and reduce substance use among Choctaw youth

  This study is testing a nature-based program to help Choctaw youth aged 12-19 be more active, eat healthier, and reduce substance use by incorporating their cultural values.

  Recruiting at 2 sites University of Washington · Durant, Oklahoma and 1 other locations · NCT05818384

• Using sit-stand desks to improve health in sedentary workers

  This study is testing if using sit-stand desks can help people with prediabetes, obesity, and metabolic syndrome who have desk jobs improve their health.

  Recruiting Medical College of Wisconsin · Milwaukee, Wisconsin · NCT05585190

• Wearable activity signatures to spot risk of additional chronic conditions

  This project tests whether wearable sensors can find activity patterns that predict new chronic conditions in people who already have chronic diseases.

  Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand · NCT05578495

• Virtual reality exercise program for women veterans

  This study is testing a new virtual reality exercise program to see if it can help women veterans improve their physical and mental health over eight weeks.

  Recruiting The University of Texas at Arlington · Arlington, Texas · NCT05563805

• Worksite wellness program to reduce sedentary behavior

  This study is testing a workplace program designed to help employees sit less and move more to see if it can make a difference in their daily activity levels over a year.

  Recruiting Arizona State University · Phoenix, Arizona · NCT05485675

• Breaking up long periods of sitting to improve heart and metabolic health

  This study is testing how often and how long people should take breaks from sitting to see if it can help improve their heart and metabolic health.

  Recruiting Columbia University · New York, New York · NCT05353322

• Reducing sedentary behavior in prostate cancer survivors

  This study is testing if a special program with support and a FitBit can help prostate cancer survivors move more and sit less over 12 weeks.

  Recruiting University of Toronto · Toronto, Ontario · NCT05214937

• Impact of Type 2 Diabetes on Muscle Loss and Recovery in Older Adults

  This study is testing how type 2 diabetes affects muscle loss and recovery in older adults during bed rest to see if it helps us understand why they lose muscle faster.

  Recruiting AdventHealth Translational Research Institute · Orlando, Florida · NCT03761446

NIH-funded research (24)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Momentum+ for Older Cancer Survivors: A mobile program to boost activity and reduce sitting

  A new mobile program for older cancer survivors uses a stepwise plan and self-determination theory to help people move more and sit less, with support from wearables and caregiver partners.

  NIH research Klein Buendel, INC. · Lakewood, UNITED STATES · NIH-11400630

• Pregnancy activity, sitting, and sleep and how they affect baby health

  This project looks at how a pregnant person's daily activity, time spent sitting, and sleep relate to their child's weight and heart health during the first two years of life.

  NIH research University of Iowa · Iowa City, United States · NIH-11372056

• Sedentary behavior and heart health in young women

  A study in young women will look at how sitting for long periods affects heart health and whether reducing sitting could lower future cardiovascular risk.

  NIH research West Virginia University · Morgantown, United States · NIH-11326192

• How preschoolers' screen habits affect sleep, activity, and emotions

  This project learns how the timing, type, and patterns of screen use in 3–5 year olds relate to their sleep, physical activity, and social-emotional health.

  NIH research University of South Carolina at Columbia · Columbia, United States · NIH-11324514

• Sitting time and Alzheimer's risk in middle-aged and older adults

  This project looks at whether spending more time sitting is linked to worse brain health and higher Alzheimer's risk in middle-aged and older adults.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11311323

• How sedentary behavior and sleep affect heart health during pregnancy

  This study is looking at how sitting too much and sleep habits affect heart health during pregnancy, especially for women who might face issues like high blood pressure, and it aims to help improve health for moms and their babies.

  NIH research University of Iowa · Iowa City, United States · NIH-11179653

• How past sports injuries and sitting habits affect later health

  This project looks at whether former athletes—especially those with past injuries—who spend a lot of time sitting have worse physical function and health in midlife.

  NIH research Marquette University · Milwaukee, United States · NIH-11171401

• Move Often Every Day: short, workday exercise breaks for receptionist office staff

  This project offers a remote, work-tailored program of 2–5 minute 'exercise snacks' plus social support to help receptionist office staff who sit a lot move more during the day.

  NIH research Stanford University · Stanford, United States · NIH-11129800

• Exploring how physical activity, sedentary behavior, and sleep affect health in older adults

  This study is looking at how staying active, sitting too much, and getting enough sleep affect the health of older adults, and it’s for anyone who wants to understand how their daily habits can help them age healthier.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11124785

• Understanding how preschoolers' screen time affects their health and behavior

  This study looks at how the time preschoolers spend on screens affects their sleep, activity levels, and feelings, helping parents understand how to manage screen time for their little ones better.

  NIH research University of South Carolina at Columbia · Columbia, United States · NIH-11112512

• Sleep, activity, and sitting: links to memory and thinking

  This project looks at how sleep, exercise, and time spent sitting relate to thinking and memory in older adults.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11092281

• Reducing sedentary behavior to prevent heart disease in young adults

  This study is looking for college students aged 18-24 to help find ways to reduce sitting time and promote healthier habits, which can help prevent heart and metabolic issues later in life.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11087603

• The impact of inactivity and sitting on the risk of Alzheimer’s disease in older adults

  This study is looking at how sitting too much might impact brain health and the risk of Alzheimer’s disease in middle-aged and older adults, and it will involve tracking your activity levels to see how staying active can help keep your mind sharp.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11083578

• Measuring Sedentary Behavior and Physical Activity in Older Adults

  This study is looking at how sitting too much or being active can impact the chances of older adults developing Alzheimer's disease and other types of dementia, using special devices to track their daily movements.

  NIH research University of Utah · Salt Lake City, United States · NIH-11082230

• The impact of sitting on heart health in young women

  This study is looking at how sitting too much can impact heart health in young women, especially those who have had tough pregnancies, and it aims to find ways to help reduce any risks related to this.

  NIH research West Virginia University · Morgantown, United States · NIH-11080929

• Finding the best ways to take short breaks from sitting to improve heart health

  This research aims to discover the most effective and comfortable ways for adults to take short breaks from sitting to help prevent heart disease.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11072049

• A smartphone program to help African Americans quit smoking and reduce sedentary behavior.

  This study is testing a smartphone program designed to help African Americans quit smoking and get more active by offering support, reminders, and rewards for making healthier choices.

  NIH research University of Oklahoma Hlth Sciences Ctr · Oklahoma City, United States · NIH-11018625

• Impact of past sports injuries and inactivity on long-term health

  This study looks at how injuries from playing sports and not being active afterward can impact the long-term health of former athletes, and it aims to find ways to help them stay healthy and feel better compared to those who never played sports.

  NIH research Marquette University · Milwaukee, United States · NIH-10914694

• Understanding how physical activity and sitting time in youth affect heart disease risk

  This study is looking at how being active or sitting too much during your teenage and young adult years can affect your heart health later in life, and it aims to find out how much exercise you really need to lower your risk of heart disease, especially if you spend a lot of time being inactive.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10909205

• How sedentary behavior and sleep affect heart health during pregnancy

  This study is looking at how sitting too much and sleep habits affect heart health during pregnancy, especially in relation to conditions like high blood pressure and preeclampsia, to help create better advice for expectant moms.

  NIH research University of Iowa · Iowa City, United States · NIH-10908383

• A program to help office workers take short exercise breaks to reduce sitting time

  This study is testing a fun new program called MOV'D that helps office workers, especially receptionists, take short exercise breaks during their day to move more and stay healthy, and it includes helpful videos and a supportive online group to keep everyone motivated.

  NIH research Stanford University · Stanford, United States · NIH-10906235

• Using telehealth to help stroke survivors become more active

  This study is testing a friendly online program designed to help stroke survivors move more and sit less, by giving them personalized tips and support to make it easier to stay active and improve their health.

  NIH research University of Minnesota · Minneapolis, United States · NIH-10896986

• Improving how we measure physical activity, sleep, and sedentary behavior using advanced data analysis techniques

  This study is working on new ways to better understand how much you move, how often you sit, and how well you sleep using movement-tracking devices, so we can learn more about how these habits affect heart health.

  NIH research Stanford University · Stanford, United States · NIH-10765650

• Investigating how physical activity and sedentary behavior affect heart failure risk in young adults and midlife.

  This study is looking at how being active or sitting too much affects the risk of heart failure in young and middle-aged adults, hoping to find ways to help people stay heart-healthy before any symptoms show up.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-10687120

Related topics

Quick answers

How many Sedentary Behavior clinical trials are recruiting right now?

28, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in United States (13 trials), Turkey (Türkiye) (3 trials), Canada (3 trials), United Kingdom (2 trials), France (2 trials). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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