Condition

Age-related Cognitive Decline clinical trials and research

• 9Clinical trials
• 5Countries

Newest Age-related Cognitive Decline clinical trials

All recruiting trials (9)

• Technology-assisted home strength training for adults 55–80 with type 2 diabetes and mild cognitive impairment

  This 12-week program will test whether a telehealth-supported home strength-training routine helps adults 55–80 with type 2 diabetes and mild cognitive impairment stick with exercise and improve strength, thinking, and blood sugar.

  Recruiting The University of Texas Medical Branch, Galveston · Galveston, Texas · NCT07416799

• Acute THC effects in older adults

  This project will see if single low or medium doses of THC cause stronger short-term effects on thinking, mood, and heart function in older adults compared with younger adults.

  Recruiting Phase 1 Yale University · West Haven, Connecticut · NCT06948136

• Mindfulness practice to improve attention and memory in older adults

  This study tests if daily mindfulness exercises with heart rate feedback can help older adults improve their attention and memory over 10 weeks.

  Recruiting University of Southern California · Los Angeles, California · NCT06410157

• Effects of changing physical activity levels on health in middle-aged adults

  This study tests how changing physical activity levels—either cutting back or increasing exercise—affects health in middle-aged adults, especially looking at issues like metabolic syndrome and cognitive decline.

  Recruiting University of Nottingham · Nottingham, Notts · NCT06377254

• Personalized multi-domain program to prevent thinking and physical decline in older adults

  This study will test whether a tailored program of exercise, a Mediterranean-style diet, cognitive training, and other health supports can help people aged 60+ at risk of cognitive decline keep their memory and daily function.

  Recruiting University of Milano Bicocca · Monza · NCT06248723

• Online tests for early detection of Alzheimer's disease

  This study is testing a new online test that helps find early signs of Alzheimer's disease in people over 50, allowing them to take it from home.

  Recruiting University of Tasmania · Hobart, Tasmania · NCT05194787

• Cognitive stimulation program for elderly patients with bipolar disorder

  This study is testing a special brain training program for older adults with bipolar disorder to see if it can help improve their thinking skills and reduce the chances of them having a relapse.

  Recruiting Groupe Hospitalier de la Rochelle Ré Aunis · La Rochelle · NCT04184375

• Cognitive training to improve function and delay dementia in older adults

  This study is testing different brain training exercises to see if they can help older adults with mild cognitive impairment improve their daily functioning and delay the onset of dementia.

  Recruiting at 5 sites University of Alabama at Birmingham · San Francisco, California and 5 other locations · NCT04171323

• Evaluating cognitive decline in older breast cancer patients

  This study is trying to see how cancer treatment affects thinking and memory in older women with breast cancer and what other factors might play a role.

  Recruiting Georgetown University · Washington D.C., District of Columbia · NCT03451383

Related topics

Quick answers

How many Age-related Cognitive Decline clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (5 trials), Italy (1 trial), United Kingdom (1 trial), France (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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