Understanding how physical activity and sitting time in youth affect heart disease risk

Informing national guidelines on adolescent and young adult physical activity and sedentary behavior to prevent cardiovascular disease

NIH-funded research University of California, San Francisco · NIH-10909205

This study is looking at how being active or sitting too much during your teenage and young adult years can affect your heart health later in life, and it aims to find out how much exercise you really need to lower your risk of heart disease, especially if you spend a lot of time being inactive.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10909205 on NIH RePORTER

What this research studies

This research investigates the relationship between physical activity and sedentary behavior during adolescence and young adulthood, and how these factors influence the risk of developing cardiovascular disease later in life. By analyzing data from large longitudinal studies, the project aims to identify the optimal levels of physical activity needed to mitigate heart disease risk for those who are highly sedentary. The findings will help inform national guidelines on physical activity for young people, emphasizing the importance of maintaining an active lifestyle during these critical developmental years.

Who could benefit from this research

Good fit: Ideal candidates for this research include adolescents and young adults aged 12 to 20 years who are interested in understanding how their physical activity levels affect their long-term heart health.

Not a fit: Patients who are already highly active and have established healthy physical activity patterns may not benefit directly from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved guidelines that help reduce the risk of cardiovascular disease in adolescents and young adults.

How similar studies have performed: Previous research has shown that physical activity significantly impacts cardiovascular health, suggesting that this approach could yield valuable insights.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.