Understanding how physical activity and sitting time in youth affect heart disease risk
Official title: Informing national guidelines on adolescent and young adult physical activity and sedentary behavior to prevent cardiovascular disease
Funded at University of California, San Francisco · NIH-10909205 · Data updated 2026-11-12
This study is looking at how being active or sitting too much during your teenage and young adult years can affect your heart health later in life, and it aims to find out how much exercise you really need to lower your risk of heart disease, especially if you spend a lot of time being inactive.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 1, 2021 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $173,910 |
| NIH project number | 5K08HL159350-04 |
| Project ID | NIH-10909205 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adolescents and young adults aged 12 to 20 years who are interested in understanding how their physical activity levels affect their long-term heart health.
✕Less likely to help
Patients who are already highly active and have established healthy physical activity patterns may not benefit directly from this research.
What this research studies
This research investigates the relationship between physical activity and sedentary behavior during adolescence and young adulthood, and how these factors influence the risk of developing cardiovascular disease later in life. By analyzing data from large longitudinal studies, the project aims to identify the optimal levels of physical activity needed to mitigate heart disease risk for those who are highly sedentary. The findings will help inform national guidelines on physical activity for young people, emphasizing the importance of maintaining an active lifestyle during these critical developmental years.
Why it matters
Potential benefit: If successful, this research could lead to improved guidelines that help reduce the risk of cardiovascular disease in adolescents and young adults.
How similar studies have gone: Previous research has shown that physical activity significantly impacts cardiovascular health, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Nagata, Jason M — University of California, San Francisco
- Study coordinator: Nagata, Jason M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.