NIH-funded research R01 grant

Measuring Sedentary Behavior and Physical Activity in Older Adults

Official title: Objectively Measured Sedentary Behavior and Physical Activity in PREVENTABLE Study

Funded at University of Utah · NIH-11082230 · Data updated 2026-11-12

This study is looking at how sitting too much or being active can impact the chances of older adults developing Alzheimer's disease and other types of dementia, using special devices to track their daily movements.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Utah
NIH-funded
Lab location1 site (Salt Lake City, United States)
Project startJuly 15, 2021
Project endMarch 31, 2026
Funding year2025
Award (this year)$518,733
NIH project number5R01AG074592-05
Project IDNIH-11082230 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults aged 75 years and above who are at risk for Alzheimer's disease or related dementias.

Less likely to help

Patients who are younger than 75 years or do not have risk factors for Alzheimer's disease may not benefit from this research.

What this research studies

This research investigates how sedentary behavior and physical activity levels affect the risk of developing Alzheimer's disease and related dementias in older adults. Using accelerometers, the study will objectively measure participants' daily activities, including how much time they spend sitting, standing, and walking. By analyzing this data, researchers aim to understand the relationship between physical inactivity and cognitive decline. The study is part of a larger trial focused on the effects of statins on cognitive function in older adults.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention strategies for Alzheimer's disease and related dementias.

How similar studies have gone: Previous research has shown that physical activity can reduce the risk of cognitive decline, but this study aims to explore the specific impact of sedentary behavior, making it a novel approach.

Where this research is happening

  • University of Utah
    Salt Lake City, United States
    Active

Researchers

  • Principal investigator: Beddhu, Srinivasan — University of Utah
  • Study coordinator: Beddhu, Srinivasan

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.