Understanding how hip muscle problems affect exercise in people with hip osteoarthritis
Official title: Quantifying the Mechanism and Impact of Hip Extensor Muscle Dysfunction During Aerobic Exercise in Hip Osteoarthritis
Funded at University of Kentucky · NIH-10873837 · Data updated 2026-11-12
This study is looking at how problems with hip muscles affect exercise for people with hip osteoarthritis, so we can help create better workout plans that make it easier for you to stay active and feel better.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project start | August 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $127,983 |
| NIH project number | 5K01AG073698-03 |
| Project ID | NIH-10873837 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals over 45 years old who are experiencing symptoms of hip osteoarthritis.
✕Less likely to help
Patients with hip osteoarthritis who do not have extensor muscle dysfunction may not benefit from this specific research.
What this research studies
This research investigates the impact of hip extensor muscle dysfunction on aerobic exercise in patients with hip osteoarthritis (OA). By developing a novel experimental platform, the study aims to precisely measure hip muscle dysfunction and its effects on exercise performance. The principal investigator will use advanced imaging techniques and muscle torque assessments to gather data that can inform better exercise programs for individuals suffering from symptomatic hip OA. The goal is to provide clinicians with the evidence needed to create effective, multidisciplinary treatment plans.
Why it matters
Potential benefit: If successful, this research could lead to more effective exercise programs that significantly improve the quality of life for patients with hip osteoarthritis.
How similar studies have gone: While there has been research on exercise interventions for hip osteoarthritis, this approach of precisely measuring muscle dysfunction is novel and has not been extensively tested.
Where this research is happening
-
University of Kentucky
Lexington, United States Active
Researchers
- Principal investigator: Samaan, Michael a — University of Kentucky
- Study coordinator: Samaan, Michael a
Related research
Other NIH-funded projects on the same topics.
-
Understanding hip osteoarthritis risk from hip shapes and genetics
Researchers will look at how the shape of the hip and genetics influence the chances of developing hip OA and needing joint replacement, using AI to study large patient data.
-
DNMT3A as a Target to Protect Hip Joints in Osteoarthritis
A patient-friendly study aims to see if turning down a specific gene pathway can slow cartilage damage in people with femoroacetabular impingement and early hip OA.
-
Bone-anchored (osseointegrated) prostheses and hip arthritis after above-knee amputation
This project compares bone-anchored (osseointegrated) prostheses with traditional socket prostheses to understand their effects on hip arthritis in people with transfemoral (above-knee) amputations.
-
Impact of bone-anchored prostheses on hip arthritis in amputees
This study is looking at how different types of leg prosthetics, one that connects directly to the bone and another that uses a socket, might affect the health of your hip joint if you've lost a leg, to help find better options for amputees.
-
Understanding how knee pain and knee obesity and muscle loss affect knee osteoarthritis
This project looks at how knee swelling, excess knee fat, and muscle loss relate to pain and structural changes in knee osteoarthritis in adults.
-
Identifying OA subtypes and early warning signs before joint damage
This grant asks researchers to find early, invisible clues of osteoarthritis subtypes so we can target treatments before joints are damaged.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.