How aerobic exercise affects muscle health in colon cancer survivors
Official title: Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colon Cancer
Funded at Adventhealth Orlando · NIH-11317318 · Data updated 2026-11-12
This study is looking at how a regular exercise program can help improve muscle health and strength in people who have survived colon cancer, with the goal of boosting their overall well-being and lowering the chances of cancer coming back.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Adventhealth Orlando NIH-funded |
| Lab location | 1 site (Orlando, United States) |
| Project start | June 3, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $717,595 |
| NIH project number | 7R01CA270274-04 |
| Project ID | NIH-11317318 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have survived colon cancer and are experiencing functional limitations or muscle health issues.
✕Less likely to help
Patients who are currently undergoing active treatment for colon cancer or those with severe comorbidities that prevent them from participating in exercise may not benefit from this research.
What this research studies
This research investigates the impact of structured aerobic exercise on skeletal muscle remodeling in individuals who have survived colon cancer. It aims to understand how physical activity can influence muscle composition, metabolic function, and overall muscle strength, which are crucial for improving health outcomes and reducing the risk of cancer recurrence. The study will involve a randomized controlled trial where participants will engage in a structured exercise program to assess these effects. By exploring these biological mechanisms, the research seeks to provide insights into how exercise can enhance the quality of life for colon cancer survivors.
Why it matters
Potential benefit: If successful, this research could lead to improved exercise recommendations that enhance recovery and reduce the risk of cancer recurrence in colon cancer survivors.
How similar studies have gone: Previous research has shown that physical activity can positively impact cancer outcomes, suggesting that this approach may yield beneficial results.
Where this research is happening
-
Adventhealth Orlando
Orlando, United States Active
Researchers
- Principal investigator: Brown, Justin C — Adventhealth Orlando
- Study coordinator: Brown, Justin C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.