Condition
Cardiovascular (CV) Risk clinical trials and research
As of November 12, 2026, Find a Trial lists 23 Cardiovascular (CV) Risk clinical trials that are recruiting, at sites in 17 countries (most in United States (8), Spain (3), Italy (3)). 1 was first registered in the last 30 days. By phase: Phase 4 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 23Clinical trials
- 1New in 30 days
- 17Countries
Newest Cardiovascular (CV) Risk clinical trials
All recruiting trials (23)
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Air filters at home to see if breathing cleaner air helps heart health in obesity
This study tests whether portable air filtration systems can improve cardiovascular risk factors in adults with obesity and high blood pressure.
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Bringing preventive cardiovascular care to Indigenous and remote communities
This project tests a mobile health unit to screen and provide culturally safe cardiovascular and metabolic care for Indigenous and remote communities in Canada.
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Breast Artery Calcification and Heart Health in Women
This study tests whether a breast artery calcification finding on a mammogram is linked to different cardiovascular markers in women 55–65 who do or do not have BAC.
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Oxidative Stress and Heart Risk in People with Rheumatoid Arthritis
This study tests whether certain markers of oxidative stress in people with rheumatoid arthritis are linked to subclinical atherosclerosis and arterial stiffness, which could relate to future heart disease risk.
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Work-Related Frustration and Higher Blood Pressure Risk in Everyday Adults
This observational study tests whether stress and frustration at work relate to blood pressure patterns that signal higher cardiovascular risk among adults aged 40–65 who are working and have no prior cardiovascular disease or blood pressure treatment.
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Cardiac risk test using breast cancer radiotherapy scans to guide decisions
This study tests whether checking coronary artery calcium on planning CT scans can help patients with breast cancer make informed heart-risk decisions during radiotherapy planning.
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CARAMEL: Personalizing Heart Risk in Women 40–60
This observational study tests a personalized cardiovascular risk-stratification approach for women aged 40–60 using multi-source data and a digital self-management tool.
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Digital, remote cardiovascular prevention versus traditional in-person care
A remote, app-guided prevention program for adults 40–75 with cardiovascular risk is compared to standard in-person care.
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Aerobic exercise to reduce heart risk in people with rheumatoid arthritis or chronic kidney disease
This program will test whether a six-week individualized aerobic exercise plan can lower heart-related risk in people with rheumatoid arthritis or stage III–IV chronic kidney disease.
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New ways to measure heart changes in sleep apnea
This study tests whether beyond-the-ordinary sleep apnea metrics can reveal cardiovascular changes and compares CPAP, MADs, and hypoglossal nerve stimulation in adults with OSA.
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Weight management program for breast cancer survivors in rural communities
This program will test whether a 12-week remote WeCan-Rural program helps rural breast cancer survivors with obesity lose weight, ease symptoms, and lower heart disease risk.
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Heart risk check for young women 3–6 years after pregnancy with or without placental complications.
This project will test an app-based algorithm to see if it can identify cardiovascular risk in women 3–6 years after giving birth, including those who had preeclampsia or low-birth-weight infants.
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RESOLVIN: Reducing cardiovascular inflammation with fish oil or camelina (plant) oil
This trial tests whether adding fish oil or camelina (plant) oil to the diet of people over 55 with moderate-to-high cardiovascular risk can lower a lipid-driven inflammation risk score.
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How menopause and HIV together affect cardiovascular disease risk in women.
This study will see if menopause combined with HIV raises heart disease risk in women with HIV by examining risk factors, inflammation, body composition, and whole-body MRI.
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Detecting hidden carotid and coronary plaque to find adults at very high heart-attack risk
This project will test whether adding carotid ultrasound and coronary exploration to the SCORE2 risk calculator finds asymptomatic adults aged 40–79 at very high risk of heart attack better than SCORE2 alone.
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How diet relates to cardiometabolic health in Rosario
This project will see how vegan, vegetarian, and omnivorous diets relate to heart and metabolic health in adults living in Rosario.
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Health and heart risk after a kidney transplant
This project will follow adults who received a kidney transplant at Royal Derby Hospital to see how cardiovascular risk factors and other health conditions change over the first year.
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Cardiovascular effects of gender-affirming hormones in adults
This project tests whether masculinizing or feminizing gender-affirming hormone therapy changes heart and blood vessel health in transgender adults who have been on hormones for at least 12 months.
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Landiolol to prevent fast heart rates during major non-cardiac surgery in patients with cardiovascular risk
This will test whether giving the ultra‑short acting beta‑blocker landiolol to people over 45 with cardiovascular risk factors who are having major non‑cardiac surgery can keep heart rate below 90 bpm throughout the perioperative period and reduce heart injury.
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Mobile app to boost cardiovascular health and exercise motivation during pregnancy
This trial will test whether using the BumptUp mobile exercise app for eight weeks helps healthy pregnant women in their second trimester increase motivation to exercise and improve cardiovascular measures.
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Heart health program for home health aides
This program tests whether a peer-coach–delivered version of the American Heart Association's Life's Essential 8 can help home health aides improve their heart health.
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Optimizing pulse (beans, lentils, peas) intake for cardiometabolic health
We will test whether eating 1.5 or 3 cups of pulses each week helps adults who currently eat less than 1.5 cups/week improve cholesterol, inflammation, blood sugar, and blood pressure.
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Analyzing how neighborhood stress affects women's heart health
This study is trying to see how stress from living in certain neighborhoods affects the heart health of women aged 19-45 in Washington, DC.
Related topics
Quick answers
How many Cardiovascular (CV) Risk clinical trials are recruiting right now?
23, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 17 countries. The most sites are in United States (8 trials), Spain (3 trials), Italy (3 trials), France (3 trials), Argentina (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.