Investigating fatigue in Veterans with chronic kidney disease through exercise
Objective and subjective measures of fatigability in Veterans with chronic kidney disease before and after flywheel resistance plus aerobic exercise
['FUNDING_OTHER'] · U.S. DEPT/VETS AFFAIRS MEDICAL CENTER · NIH-10938014
This study is looking at how tiredness affects Veterans with chronic kidney disease and whether a special exercise program that mixes strength and aerobic workouts can help them feel less fatigued and improve their physical abilities.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | U.S. DEPT/VETS AFFAIRS MEDICAL CENTER (nih funded) |
| Locations | 1 site (WASHINGTON, UNITED STATES) |
| Trial ID | NIH-10938014 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how fatigue affects Veterans with chronic kidney disease (CKD) and explores the impact of a specific exercise program combining flywheel resistance exercise and aerobic training. The study aims to assess both objective and subjective measures of fatigability before and after the exercise intervention. By examining the relationship between neuromuscular capacity and fatigue, the research seeks to determine if this combined exercise approach can enhance physical function and reduce fatigue levels in affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are Veterans diagnosed with stage 3 or 4 chronic kidney disease who experience significant fatigue.
Not a fit: Patients with advanced chronic kidney disease requiring dialysis or those with other severe comorbidities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved exercise interventions that enhance physical function and reduce fatigue in Veterans with chronic kidney disease.
How similar studies have performed: Previous research has shown that flywheel resistance exercise can improve muscle strength and function in healthy populations, suggesting potential benefits for Veterans with CKD, although this specific combination approach is relatively novel.
Where this research is happening
WASHINGTON, UNITED STATES
- U.S. DEPT/VETS AFFAIRS MEDICAL CENTER — WASHINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOLLIE, JARED M. — U.S. DEPT/VETS AFFAIRS MEDICAL CENTER
- Study coordinator: GOLLIE, JARED M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: chronic kidney disease, Chronic Renal Disease