Comparison of Different Exercise Protocols for Lipedema

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares two aerobic exercise programs in adults aged 18–65 with lipedema who have not recently trained. Participants are assigned to either high‑intensity interval aerobic exercise or moderate‑intensity continuous exercise to measure changes in functional capacity, muscle strength, and quality of life. Outcomes will help determine which training approach is more effective for this population. The study is conducted at Hitit University, with the lead sponsor coordinating the effort.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18-65 years and diagnosed with lipedema.
* Have not participated in a structured exercise training program within the previous 3 months.
* Voluntarily agree to participate in the study and provide informed consent.

Exclusion Criteria:

* Presence of cardiopulmonary, rheumatologic, or neurological conditions causing symptoms of sufficient severity to prevent participation in the exercise program.
* History of cancer or presence of thyroid disorders.
* Presence of edema primarily attributable to conditions other than lipedema, including lymphedema, venous edema, or edema secondary to heart or renal failure.
* Body mass index (BMI) \> 50.0 kg/m².

Where it's running

• Hitit University
  Çorum, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Ayla Cağlıyan Turk
• Email: drayla1976@hotmail.com
• Phone: +095334314171

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Kinesio Taping Added to Standard Care for Women with Lipedema

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• Comparison of body composition in lipedema and obesity

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• taVNS-enriched rehab for lipedema

  This study tests whether adding transcutaneous auricular vagus nerve stimulation (taVNS) to standard rehabilitation helps people with lipedema reduce symptoms.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, Eyupsultan · NCT07857499

• Manual and self-lymphatic drainage with exercise for lipedema

  This study tests whether manual lymph drainage plus supervised exercise works better than self-lymph drainage plus guided activity for reducing pain and improving function in women with lipedema over six weeks.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, Eyupsultan · NCT07803926

• Turkish version of the Duke Activity Status Index in women with lipedema

  This study tests whether the Turkish Duke Activity Status Index accurately and consistently measures functional capacity in women with lipedema.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, Eyupsultan · NCT07803913

• Aquatic vs. land-based exercise for lipedema in women

  This trial tests whether supervised pool workouts or equivalent land-based exercise improve walking ability and symptoms more than standard care for women with lipedema.

  Recruiting Cairo University · Giza, Dokki · NCT07756463

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.