Using aerobic exercise to enhance mobility in people with multiple sclerosis
Aerobic exercise to improve mobility in multiple sclerosis: optimizing design and execution for a full-scale multimodal remyelination clinical trial
This study is looking at how aerobic exercise might help people with multiple sclerosis move better and repair their nerves, and it’s for anyone with MS who wants to see if exercise can make a positive difference in their condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-10864030 on NIH RePORTER |
What this research studies
This research investigates how aerobic exercise can improve mobility and promote remyelination in individuals with multiple sclerosis (MS). It aims to identify the best ways to measure remyelination and assess the effectiveness of an aerobic exercise intervention. By combining rehabilitative therapies with pharmacological treatments, the study seeks to enhance the conduction of nerve signals and reduce disability associated with MS. The research will involve both animal models and human participants to establish a reliable approach for future clinical trials.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with multiple sclerosis who experience mobility challenges.
Not a fit: Patients with other neurological conditions or those who do not have mobility issues related to multiple sclerosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved mobility and quality of life for patients with multiple sclerosis.
How similar studies have performed: Previous research has shown that aerobic exercise can promote remyelination in animal models, indicating potential for success in human studies.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Wooliscroft, Lindsey Brianna — Oregon Health & Science University
- Study coordinator: Wooliscroft, Lindsey Brianna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.