Clinical trial Recruiting at 1 site Interventional Ages 18 to 80 Women only

Combined upper-body resistance and aerobic exercise program for people treated for breast cancer

Official title: Investigation of the Effect of Combined Upper Extremity Resistance and Aerobic Exercise Training on Arm Exercise Capacity, Peripheral Muscle Strength and Arm Functionality in Patients With Breast Cancer

Run by Hacettepe University · NCT07070791 · Data updated 2026-11-12

This program will test whether a combined upper-body resistance and aerobic exercise routine helps people at least 15 months after breast cancer surgery improve arm function, strength, and symptoms.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexWomen only
Enrollment40 (estimated)
SponsorHacettepe University
Academic / other
Locations1 site (Ankara, State)
StatusRecruiting
StartedJuly 8, 2025
Main results expectedNovember 1, 2026
Study endsDecember 1, 2026
Registry record updatedSeptember 16, 2026
Trial IDNCT07070791 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18–80 years old who are physically inactive, at least 15 months after breast cancer surgery, and able to complete questionnaires and exercise testing are ideal candidates.

Probably not a fit

Patients with bilateral breast cancer, active infection, unstable hypertension or diabetes, symptomatic heart or lung disease, significant neurological or musculoskeletal conditions, or major cognitive impairment are unlikely to benefit or may be excluded.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults aged 18–80 who are physically inactive and at least 15 months after breast cancer surgery will be enrolled. Participants will follow a combined intervention of progressive upper-extremity resistance exercises (using elastic bands) plus upper-body aerobic training, with intensity increased over time. Outcomes will be measured before and after the intervention and likely include upper-limb strength, shoulder function, pain, signs of lymphedema, and quality of life. The protocol excludes those with bilateral disease, active infection, unstable cardiovascular or metabolic conditions, significant neurologic or musculoskeletal impairments, or other comorbidities that would prevent safe exercise.

Why it matters

Potential benefit: If successful, the program could improve arm strength and shoulder function, reduce pain and lymphedema-related symptoms, and enhance quality of life.

How similar studies have gone: Prior research of resistance and aerobic exercise in breast cancer survivors has shown improvements in strength, fatigue, and quality of life, although combined upper-extremity–focused programs are less commonly studied.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* To be between 18-80 years old,
* Volunteering to participate in the research,
* At least 15 months after breast cancer surgery,
* No problems in reading and/or understanding the scales and being able to co-operate with the tests.
* Physically inactive (60 minutes of structured exercise per week \<).

Exclusion Criteria:

* Presence of active infection,
* Presence of bilateral breast cancer,
* History of surgical, neurological or orthopaedic problems that may affect upper extremity functionality other than breast cancer surgery,
* Having a neurological disease or other clinical diagnosis that may affect cognitive status,
* Musculoskeletal and neurological disease that may affect exercise performance, symptomatic heart disease, previous lung surgery and malignant disease.
* Presence of unstable hypertension or diabetes mellitus.

Where it's running

  • Hcettepe University
    Ankara, State, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.