How exercise affects brain health and Alzheimer's risk in older African Americans

Determinants of Individual Differences in the Efficacy of Aerobic Exercise to Improve Brain Health and Reduce Alzheimer Disease Risk in Older African Americans

NIH-funded research Rutgers the State Univ of Nj Newark · NIH-10909220

This study is exploring how aerobic exercise, like cardio-dance, can boost brain health and lower the risk of Alzheimer's disease in older African Americans, while also looking at how genetics might affect how well exercise works for different people.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers the State Univ of Nj Newark NIH-funded
Lab location1 site (Newark, United States)
Project IDNIH-10909220 on NIH RePORTER

What this research studies

This research investigates how aerobic exercise can improve brain health and reduce the risk of Alzheimer's disease specifically in older African Americans. It focuses on understanding why some individuals respond better to exercise than others, particularly looking at genetic factors that may influence this response. The study will involve participants engaging in aerobic activities, such as cardio-dance, to assess changes in brain function and cognitive abilities over time. By identifying the relationship between exercise, genetics, and brain health, the research aims to provide tailored recommendations for improving health outcomes in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are older African Americans, particularly those with a family history of Alzheimer's or those living in urban areas with limited access to exercise resources.

Not a fit: Patients who are not African American or those who do not fall within the older age demographic may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to personalized exercise programs that significantly lower the risk of Alzheimer's disease for older African Americans.

How similar studies have performed: Previous studies have shown that aerobic exercise can enhance brain function, particularly in older adults, suggesting a promising avenue for further exploration in this specific population.

Where this research is happening

Newark, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.