Aerobic exercise to boost stroke rehabilitation outcomes with a VR game
Official title: Priming the Rehabilitation Engine: Aerobic Exercise as the Fuel to Spark Behavioral Improvements in Stroke
Funded at Ralph H Johnson VA Medical Center · NIH-11493622 · Data updated 2026-11-12
A VA-based study tests whether an aerobic workout before a hand-rehabilitation game can improve recovery after stroke for veterans.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ralph H Johnson VA Medical Center NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project start | February 1, 2021 |
| Project end | January 31, 2027 |
| Funding year | 2027 |
| NIH project number | 5IK2RX003540-06 |
| Project ID | NIH-11493622 on NIH RePORTER |
Who could benefit from this research
✓Could help
Veterans and others recovering from stroke who would participate in upper-extremity rehabilitation using the Duck Duck Punch game.
✕Less likely to help
Patients not undergoing upper-extremity rehabilitation or those unable to participate in aerobic exercise may not benefit.
What this research studies
This project explores using aerobic exercise to ‘prime’ the brain before engaging in a targeted upper-extremity rehabilitation game called Duck Duck Punch. By combining aerobic activity with a virtual reality game, the researchers aim to create a brain environment that is more receptive to motor learning and recovery after stroke. The study focuses on veterans and measures functional and cognitive improvements, along with potential brain plasticity markers, to see if the prep workout enhances rehabilitation gains. If successful, this approach could become a practical addition to post-stroke care to maximize benefits from therapy sessions.
Why it matters
Potential benefit: If the approach works, veterans recovering from stroke could experience greater improvements in arm function and overall quality of life after rehabilitation.
How similar studies have gone: Prior evidence suggests aerobic exercise can support neuroplasticity and improve rehabilitation outcomes, with emerging data on priming effects.
Where this research is happening
-
Ralph H Johnson VA Medical Center
Charleston, United States Active
Researchers
- Principal investigator: Ross, Ryan — Ralph H Johnson VA Medical Center
- Study coordinator: Ross, Ryan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.