Upper-arm aerobic exercise for arterial stiffness in women treated for breast cancer.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study enrolls women after breast cancer surgery to measure arterial stiffness before and after a program of upper-extremity aerobic exercise, examining both acute and chronic responses. Participants must have preserved cardiac function (LVEF >50%) and no significant coronary or carotid disease; those with active infection, bilateral disease, or major neurologic/musculoskeletal limitations are excluded. The intervention involves structured arm aerobic training sessions delivered onsite at Hacettepe University, with vascular measurements taken at baseline and after the training period. Results aim to clarify whether targeted arm exercise improves arterial stiffness and arm function in breast cancer survivors.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* To be between the ages of 40-69,
* Baseline left ventricular ejection fraction (LVEF) \>50%,
* Absence of coronary artery disease and haemodynamically significant valvular heart disease,
* Absence of carotid atherosclerotic plaques,
* Volunteering to participate in the research,
* At least 15 months after breast cancer surgery,
* No problems in reading and/or understanding the scales and being able to co-operate with the tests.
* Physically inactive (60 minutes of structured exercise per week \<).

Exclusion Criteria:

* Presence of active infection,
* Presence of bilateral breast cancer,
* History of surgical, neurological or orthopaedic problems that may affect upper extremity functionality other than breast cancer surgery,
* Having a neurological disease or other clinical diagnosis that may affect cognitive status,
* Left ventricular dysfunction and severe liver and kidney dysfunction before starting chemotherapy
* Musculoskeletal and neurological disease that may affect exercise performance, symptomatic heart disease, previous lung surgery and malignant disease.
* Presence of unstable hypertension or diabetes mellitus.

Where it's running

• Hacettepe University
  Ankara, State, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Ebru Calik Kutukcu, PhD
• Email: ebru.calik@hacettepe.edu.tr
• Phone: +903123051576

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.