Improving energy and strength in Veterans with chronic kidney disease using flywheel resistance plus aerobic exercise
Official title: Objective and subjective measures of fatigability in Veterans with chronic kidney disease before and after flywheel resistance plus aerobic exercise
Funded at U.s. Dept/vets Affairs Medical Center · NIH-11220695 · Data updated 2026-11-12
This project sees whether adding aerobic workouts to flywheel resistance training can reduce tiredness and boost strength in Veterans with stage 3–4 chronic kidney disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | U.s. Dept/vets Affairs Medical Center NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project start | October 1, 2020 |
| Project end | March 31, 2027 |
| Funding year | 2026 |
| NIH project number | 5IK2RX003423-06 |
| Project ID | NIH-11220695 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are Veterans with stage 3 or 4 chronic kidney disease who are not yet on dialysis and who can safely take part in supervised exercise.
✕Less likely to help
People already on dialysis, with unstable cardiac or medical conditions, or who cannot perform exercise are unlikely to benefit from or be eligible for this program.
What this research studies
You would join a supervised exercise program for Veterans with stage 3–4 chronic kidney disease that uses flywheel resistance workouts, with some participants also doing regular aerobic sessions. Before and after the training period, the team will measure how quickly your muscles tire on physical tests and ask about how tired you feel during daily life. They will also measure muscle strength, power, and functional tasks like walking or getting up from a chair to track changes. The goal is to find out if combining aerobic work with flywheel resistance gives extra benefits without reducing strength or function.
Why it matters
Potential benefit: If successful, this approach could reduce fatigue and improve muscle strength and daily function for Veterans with moderate chronic kidney disease.
How similar studies have gone: Flywheel resistance training has improved strength and function in healthy adults, but combining it with aerobic training in people with CKD is a new application that has not yet been proven.
Where this research is happening
-
U.s. Dept/vets Affairs Medical Center
Washington, United States Active
Researchers
- Principal investigator: Gollie, Jared M. — U.s. Dept/vets Affairs Medical Center
- Study coordinator: Gollie, Jared M.
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.