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Clinical trials and research at Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

• 118Clinical trials
• 4New in 30 days
• 2Countries

Newest trials

All recruiting trials (118)

• Candonilimab with Fruquintinib and Paclitaxel Albumin-Bound as second-line treatment for advanced gastric cancer

  This phase 2 trial tests whether adding candonilimab to fruquintinib and nab-paclitaxel helps people with advanced gastric or gastroesophageal junction cancer who progressed after first-line therapy.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07920224

• Pulse Wave vs Saline Bolus EIT to measure lung perfusion in ARDS

  This study tests whether pulse wave EIT or saline bolus EIT can best show lung blood flow in ARDS patients on mechanical ventilation.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07908368

• AI-powered CT help to guide pneumonia care

  A multicenter trial tests whether using a chest CT–based AI report to guide care reduces death or need for new organ support in adults with pneumonia.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07895290

• AI-assisted longitudinal CT to guide indeterminate lung nodules

  This trial tests whether giving doctors an AI report that tracks nodules over serial CT scans helps reduce unnecessary benign lung resections in patients with indeterminate nodules.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07895277

• Low-Dose CBCT AI Model for Interventions

  This trial tests a low-dose CBCT AI model to guide image-guided interventional procedures for adults requiring CBCT during brain, lung, or liver interventions.

  Recruiting at 5 sites Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Hefei, Anhui and 4 other locations · NCT07845929

• Dalpiciclib with an aromatase inhibitor and olmesartan as first-line therapy for HR+/HER2- advanced breast cancer

  This trial tests whether adding dalpiciclib and olmesartan to an aromatase inhibitor helps people with HR+/HER2- advanced breast cancer respond to first-line treatment.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07810088

• Iparomlimab and Tuvonralimab with Lenvatinib, Radiotherapy, and HAIC in HCC with PVTT

  This trial tests a multi-drug approach to see if it can control liver cancer that has grown into the portal vein in adults.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07776080

• Gastric cancer: using pretreatment CT and clinical data to predict outcomes

  A previously developed CT-based model that combines imaging features with clinical data is being tested to see if it can predict survival and progression in adults with gastric cancer before treatment.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07776067

• Retlirafusp alfa with bevacizumab and chemotherapy (with or without short radiotherapy) for colorectal cancer liver metastases

  This study tests whether adding retlirafusp alfa to bevacizumab and chemotherapy, with or without short-course radiotherapy, can help patients with advanced colorectal cancer that has spread to the liver.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07728019

• Endovascular Therapy for Posterior Circulation Stroke After 1 Day

  This trial tests whether adding endovascular treatment to standard care helps adults with posterior circulation stroke who last well more than 24 hours ago.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07699029

• Ga-ELI421 PET imaging in prostate cancer

  This study tests a single dose of Ga-ELI421 PET imaging to see if it is safe and useful for people with prostate cancer.

  Recruiting Phase 1/2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07689656

• Safety and activity of radioligand therapy with RTX-2358 plus immune therapy in FAP-positive metastatic NSCLC

  A small, early study tests whether giving a targeted radioligand to patients with FAP-positive metastatic NSCLC, combined with a PD-1 inhibitor, is safe and shows signs of activity.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07689643

• Anti-CD25 antibody to prevent acute GVHD after haploidentical stem cell transplant

  This study tests whether an anti-CD25 antibody can better prevent acute graft-versus-host disease after haploidentical hematopoietic stem cell transplantation compared with the usual methotrexate-based approach.

  Recruiting Phase 3 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07689630

• Metabolic and Functional Study of γδ T Cells in Critically Ill Patients

  Researchers will look at how γδ T cells behave in severely ill patients, including those with sepsis, to see how their metabolism and function change.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Outside of the US · NCT07680816

• Pirfenidone plus PD-1 inhibitor with or without targeted radiotherapy for advanced colorectal cancer

  This study tests whether combining pirfenidone with a PD-1 inhibitor, with or without hypofractionated radiotherapy, is safe and helps people with unresectable or metastatic pMMR/MSS colorectal cancer who have exhausted standard therapies.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07644286

• Madecassoside tablets plus standard therapy for sclered scl-cGVHD after allo-HSCT

  This study tests whether adding madecassoside tablets to standard therapy can help people with scleral chronic graft-versus-host disease after stem cell transplant.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07606703

• IN026 for adults with refractory gout

  This study tests whether IN026 injections can safely lower uric acid in adults with gout that hasn’t responded to standard treatments.

  Recruiting Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan · NCT07587684

• Moxibustion with second-line treatment for steroid-refractory acute graft-versus-host disease after transplant

  This study will test whether adding moxibustion to standard second-line drug therapy helps people aged 14–65 with steroid-refractory gastrointestinal acute GVHD after an allogeneic stem cell transplant.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07572669

• T-cell–guided letermovir stopping after allogeneic stem cell transplant

  This tests whether using a CMV-specific T-cell blood test to decide when adult CMV-positive patients can stop letermovir after allogeneic stem cell transplant keeps them protected while avoiding unnecessary drug exposure.

  Recruiting Phase 4 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Beijing, Beijing Municipality and 11 other locations · NCT07569653

• LRRC15-targeted PET imaging for more precise diagnosis and staging of pancreatic, breast, lung, sarcoma and head-and-neck cancers

  This project tests whether an LRRC15-targeted PET scan can better detect and stage LRRC15-expressing cancers and measures how the tracer behaves in healthy adults.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07552467

• CT1182 CAR‑T infusion for adults with relapsed or refractory B‑cell non‑Hodgkin lymphoma

  This trial tests whether a CT1182 CAR‑T cell infusion is safe and can help adults 18–75 with relapsed or refractory B‑cell non‑Hodgkin lymphoma.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07548697

• Phase II UC‑MSC treatment for knee osteoarthritis

  This Phase II trial will try whether injections of umbilical-cord-derived mesenchymal stem cells into the knee help adults 40–70 with knee osteoarthritis reduce pain and repair cartilage compared with a placebo.

  Recruiting at 3 sites Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan and 2 other locations · NCT07547735

• FL-261 imaging to detect and stage c-MET–expressing cancers

  This first-in-human test uses FL-261 labeled for PET or SPECT to see if it safely highlights c-MET–positive tumors in adults with advanced solid tumors such as non-small cell lung, colorectal, or head and neck cancer.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07510321

• YKST02 for adults with primary IgA nephropathy.

  This trial will test whether intravenous YKST02 is safe and can reduce urine protein in adults with primary IgA nephropathy who have persistent proteinuria despite standard treatment.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07498673

• Short-course radiation followed by liposomal irinotecan, oxaliplatin, capecitabine and sintilimab before surgery for high-risk rectal cancer

  This treatment plan tests whether a short course of radiation followed by six cycles of liposomal irinotecan, oxaliplatin, capecitabine and the immunotherapy drug sintilimab before surgery can shrink tumors and let some people with newly diagnosed high-risk, locally advanced rectal cancer avoid immediate surgery.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan · NCT07474103

• EVM18001 for adults with refractory lupus, myasthenia gravis, and scleroderma

  This single-arm study will test an experimental CAR‑T therapy called EVM18001 to see if it is safe and helps adults whose lupus, myasthenia gravis, or scleroderma did not respond to standard treatments.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07470151

• Universal CAR‑T (CT1190B) for CD19 and/or CD20 positive relapsed/refractory B‑cell acute lymphoblastic leukemia in patients aged 12–75

  This trial will test whether an off‑the‑shelf CAR‑T product (CT1190B) is safe and can induce remission in CD19 and/or CD20 positive relapsed or refractory B‑cell acute lymphoblastic leukemia for patients aged 12–75.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07470073

• UCAR-T cells targeting CD19 and BCMA for autoimmune blood disorders

  This treatment tests an off-the-shelf UCAR-T cell therapy that targets CD19 and BCMA to try to treat adults with antibody-driven blood disorders like ITP, autoimmune hemolytic anemia, and Evans syndrome.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07441525

• QI-019A CAR-T therapy for relapsed/refractory multiple myeloma

  A single-arm study tests whether the QI-019A CAR-T therapy is safe and shows signs of activity in adults with relapsed or refractory multiple myeloma.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07429721

• Becotatug Vedotin plus Zimberelimab in recurrent/metastatic cervical, vulvar, and vaginal cancers

  This study tests a targeted cancer drug linked to a toxin with a PD-1 blocker in women with recurrent or metastatic cervical, vulvar, or vaginal cancers who have already tried standard therapies.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07424664

• Cadonilimab with chemotherapy followed by concurrent chemoradiotherapy for locally advanced cervical cancer

  This phase 3 study will test whether adding cadonilimab to initial chemotherapy and then giving standard concurrent chemoradiotherapy helps women aged 18–70 with stage IIB–IVA locally advanced cervical cancer have better tumor responses and outcomes than standard chemoradiotherapy alone.

  Recruiting Phase 3 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07400536

• CT1195E CAR-T cell therapy for refractory or progressive systemic sclerosis

  This trial will test whether CT1195E CAR-T cell therapy is safe and helps adults (18–60) with refractory or progressive systemic sclerosis.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07355972

• Fecal microbiota transplant to treat ICU delirium

  This trial will test whether transferring healthy gut bacteria (fecal microbiota transplantation) can help adults in the ICU who have delirium.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan · NCT07348471

• A-319 for active rheumatoid arthritis

  This trial will test whether A-319 is safe and tolerable and may help people with active rheumatoid arthritis who have not responded to multiple prior therapies.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07347860

• Universal CD19/CD20 CAR-T cell injection for moderate to severe refractory systemic lupus erythematosus

  This study will try a universal CD19/CD20 CAR‑T cell infusion (CT1195E) to see if it is safe and helps adults 18–65 with moderate to severe refractory SLE.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07339332

• IASO208 injection for relapsed or refractory B‑cell lymphomas

  This trial will test IASO208 injections in adults (18–75) whose B‑cell lymphoma has relapsed or not responded to prior standard treatment to see if it is safe and helps control the disease.

  Recruiting Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07309900

• PET imaging that targets PSMA, CAIX, and CD70 to detect and stage renal cell carcinoma.

  This project will test whether PET scans that target PSMA, CAIX, and CD70 can accurately detect and map renal cell carcinoma in adults with suspected or confirmed disease and in healthy volunteers.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07301827

• PET imaging that targets CLDN18.2 to find stomach, pancreatic, bile-duct, and esophageal cancers

  This project will try a CLDN18.2-targeted PET scan in adults with suspected or confirmed gastric, pancreatic, bile-duct, or esophageal cancer (and some healthy volunteers) to see if it can show CLDN18.2-positive tumors.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07301814

• 68Ga-FL-031 PET for diagnosing and staging cancer

  This project will test whether 68Ga-FL-031 PET imaging, compared with 18F-FDG PET, can detect and stage small cell lung cancer, breast cancer, nasopharyngeal carcinoma and other tumors in adults.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07301801

• TIPS procedure with or without oral branched-chain amino acids (BCAA)

  This test will try giving oral BCAA supplements for three months after TIPS in adults with cirrhosis and sarcopenia to see if it improves muscle and clinical outcomes.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan · NCT07281846

• Deep learning reconstruction for clearer cardiac MRI scans

  This project tests whether AI-based MRI sequences produce better heart images for adults who need a cardiac MRI.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07274436

• Using deep learning reconstruction for ankle MRI images

  We will try AI-based MRI scanning for adults with ankle injuries to see if it gives clearer diagnostic images than standard MRI.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07274423

• Safety and effectiveness of ZZSW-01 for relapsed or refractory B-cell cancers

  This trial will try injections of ZZSW-01, an extracellular vesicle that delivers CD19 CAR mRNA, in adults with relapsed or refractory CD19‑positive B‑cell cancers to see if it is safe and helps control the disease.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan · NCT07240974

• β-hydroxybutyrate with short-course radiotherapy, immunotherapy and CAPEOX before surgery for locally advanced rectal cancer

  This phase II trial will test whether adding β-hydroxybutyrate supplements to short-course radiotherapy followed by immunotherapy plus CAPEOX chemotherapy improves outcomes for people with locally advanced rectal cancer before surgery.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07239466

• AI-based body composition mapping from CT scans to predict outcomes after TACE for liver cancer

  This project will test whether an AI that analyzes routine CT scans can help predict survival and treatment response for adults with hepatocellular carcinoma who receive TACE.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07235410

• Enteral phosphate granules to treat low blood phosphate (hypophosphatemia)

  This trial will test whether giving enteral sodium dihydrogen phosphate and disodium hydrogen phosphate granules to adult ICU patients with low blood phosphate raises their serum phosphorus and is safe.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07233889

• Serplulimab with Induction Chemotherapy and Radiotherapy in Locally Advanced Nasopharyngeal Carcinoma

  This phase 3 trial tests whether giving serplulimab with induction chemotherapy and radiotherapy, then maintenance therapy, can help people with locally advanced nasopharyngeal cancer who respond well to initial chemotherapy.

  Recruiting Phase 3 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07177443

• How TIPS affects liver recompensation in people with decompensated cirrhosis

  This observational project will see if placing a transjugular intrahepatic portosystemic shunt (TIPS) helps adults (18–80) with decompensated cirrhosis from treatable causes to achieve liver recompensation and improve survival.

  Recruiting at 15 sites Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Changsha and 14 other locations · NCT07172035

• CT-based AI to predict outcomes after kidney cancer surgery

  This project will try CT-based AI models to predict post-surgery outcomes for adults treated for kidney cancer.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07118813

• Long-course versus short-course radiotherapy before immunotherapy and total neoadjuvant therapy for locally advanced rectal cancer

  This trial tests whether adding immunotherapy to total neoadjuvant therapy and using short-course versus long-course radiotherapy improves outcomes for adults with locally advanced rectal cancer.

  Recruiting Phase 3 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07113275

• OriV508 injection for relapsed or refractory multiple myeloma and aggressive B‑cell lymphoma

  We will try OriV508, an in‑body lentiviral therapy carrying a BCMA/CD19 dual‑target CAR, in adults whose multiple myeloma or aggressive B‑cell lymphoma has returned or not responded to prior treatments.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07101705

• High-dose firmonertinib plus chemotherapy injected into the spinal fluid for EGFR-mutant NSCLC with leptomeningeal spread

  This tests whether high-dose firmonertinib combined with chemotherapy injected into the spinal fluid helps people with EGFR-mutant non-small cell lung cancer that has spread to the leptomeninges.

  Recruiting Phase 4 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07092202

• Pulmonary rehabilitation for people with COPD who also have heart or stroke-related vascular disease

  We will test if adding a three-month pulmonary rehabilitation program to usual care helps adults with COPD who also have cardiovascular or cerebrovascular disease reduce flare-ups and improve breathing and quality of life.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07090200

• Using AI on CT and MRI scans to predict immunotherapy response and survival for liver cancer patients

  This project will test whether artificial intelligence applied to CT and MRI scans can predict which adults with hepatocellular carcinoma will respond to immunotherapy and their likely survival.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07059936

• AI and CT-based prediction of immunotherapy response in lung cancer patients

  This project will try to use CT scans and artificial intelligence to predict whether adults with lung cancer will respond to immunotherapy.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07059923

• ct1192 CD19/CD20 CAR‑T cell therapy for moderate to severe refractory SLE

  This study will try one infusion of ct1192 universal CD19/20 CAR‑T cells in adults with moderate to severe lupus that has not responded to standard treatments.

  Recruiting Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07031713

• UTAA91 injection for refractory rheumatoid arthritis

  This trial will test whether injecting UTAA91 is safe for adults with moderate-to-severe rheumatoid arthritis that has not responded to standard treatments.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07001956

• UTAA91 injection for refractory systemic sclerosis

  This trial will test whether UTAA91 injections are safe and tolerable in adults with refractory moderate-to-severe systemic sclerosis.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT07000682

• FL-091 NTSR1-targeted imaging for finding and staging NTSR1-positive tumors

  This project will test whether a new NTSR1-targeted imaging agent called FL-091 can help find and stage NTSR1-expressing cancers in adults.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06977945

• Prognostic model for Acute Respiratory Distress Syndrome using Electrical Impedance Tomography

  This study is trying to see if a new way of measuring lung function can help doctors predict how well patients with Acute Respiratory Distress Syndrome (ARDS) will do and tailor their treatment accordingly.

  Recruiting at 4 sites Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Guangzhou, Guangdong and 3 other locations · NCT06967207

• Cizutamig for refractory seropositive rheumatoid arthritis

  This trial tests whether cizutamig, a BCMAxCD3 T‑cell engager, is safe and can help adults with seropositive rheumatoid arthritis that has not responded to other treatments.

  Recruiting Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06946199

• AI-assisted vs surgeon-planned screw paths for freehand femoral neck fixation

  This trial will test whether AI-assisted planning leads to more accurate screw placement, shorter operative time, and less radiation for adults having cannulated screw fixation of femoral neck fractures.

  Recruiting at 4 sites Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan and 3 other locations · NCT06937138

• Protein A immunoadsorption for dilated cardiomyopathy with anti–β1-adrenergic receptor antibodies

  This trial tests whether Protein A immunoadsorption can improve heart function and outcomes in adults with dilated cardiomyopathy who have anti–β1-adrenergic receptor antibodies.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06922851

• Improving radiology report writing with artificial intelligence

  This study is testing if using artificial intelligence can help radiologists write better reports compared to those who don’t use the AI.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06907927

• Clinical Application of PET Imaging Targeting MSLN in Malignant Tumors

  This study is testing if a special type of PET scan that targets a protein in cancer cells can help doctors find and treat malignant tumors better.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06843629

• Using sorbitol with chemotherapy and immunotherapy for advanced gastric cancer

  This study is testing if adding sorbitol to standard chemotherapy and immunotherapy can help people with advanced gastric cancer feel better and improve their treatment results.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06826079

• Short-course radiotherapy followed by AK112 and CAPOX for advanced rectal cancer

  This study is testing a new treatment plan that combines short radiation therapy with two medications for people with advanced rectal cancer to see if it works better than the usual treatments.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Hubei · NCT06802666

• How TIPS may improve muscle loss in cirrhosis and the role of FGF21

  This project tests whether TIPS helps people with cirrhosis regain muscle and whether blood FGF21 levels explain that improvement.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan · NCT06794853

• Using blood tests to identify bacteria in ICU patients with sepsis

  This study is testing a new blood test to see if it can help doctors find harmful bacteria in ICU patients with sepsis so they can better track infections and improve patient care.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan · NCT06791889

• Comparing low tidal volume and airway pressure release ventilation for ARDS patients

  This study tests which breathing method, low tidal volume or airway pressure release ventilation, helps adults with Acute Respiratory Distress Syndrome breathe better and feel safer while on a ventilator.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06790875

• Evaluating antibodies in patients with viral myocarditis and their risk of heart disease

  This study is testing whether certain antibodies in patients with viral myocarditis can help predict their risk of developing serious heart problems later on.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06742008

• Evaluating the impact of specific antibodies in patients with dilated cardiomyopathy

  This study is trying to see if certain antibodies in people with dilated cardiomyopathy can help predict their heart health and outcomes over three years.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06741995

• Treatment of relapsed/refractory B cell tumors using bispecific CAR T cells

  This study is testing a new type of CAR T cell therapy that targets two specific proteins to see if it can help people with stubborn B cell tumors that haven't responded to other treatments.

  Recruiting Phase 1/2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06735495

• Cell injection for patients with relapsed or refractory CD7-positive NK/T cell malignancies

  This study is testing a new cell therapy for people with hard-to-treat CD7-positive NK/T cell lymphoma to see if it is safe and helps improve their condition.

  Recruiting Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06732492

• Treatment of CD7-positive blood cancers using CAR-T cells

  This study is testing a new CAR-T cell therapy designed to target CD7 in patients with certain blood cancers that haven't responded to other treatments.

  Recruiting Phase 1/2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06720324

• Combining IBI363 with Bevacizumab or Furuitinib for Advanced Colorectal Cancer

  This study is testing if a new drug called IBI363, when combined with either Bevacizumab or Furuitinib, can help adults with advanced colorectal cancer who haven't responded to standard treatments.

  Recruiting Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06717880

• Effects of Lung Impedance Tomography on Breathing in ARDS Patients

  This study tests if using a special lung monitoring technique can improve breathing and blood flow in patients with acute respiratory distress syndrome by adjusting their ventilation settings.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06696638

• Evaluating AcNK-Sup003 Cell Injection for B-cell Non-Hodgkin's Lymphoma

  This study is testing if a new type of cell injection can help people with hard-to-treat B-cell non-Hodgkin's lymphoma by boosting the body's natural killer cells to fight the cancer.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06693973

• Combining chemotherapy and immune therapy with heated chemotherapy for gastric cancer with peritoneal spread

  This study is testing a new treatment that combines heated chemotherapy with regular chemotherapy and immune therapy to see if it helps people with advanced gastric cancer that has spread to the lining of the abdomen.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06685887

• IN10018 plus nab-paclitaxel and cadonilimab for metastatic or recurrent gastric-type cervical adenocarcinoma.

  This trial will test whether combining IN10018 with nab-paclitaxel and cadonilimab helps adult women whose gastric-type cervical adenocarcinoma has come back or spread after prior chemotherapy.

  Recruiting at 2 sites Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei and 1 other locations · NCT06654011

• Short-term radiotherapy followed by chemotherapy for advanced rectal cancer

  This study is testing a new treatment plan that combines short-term radiation and chemotherapy to see if it helps people with advanced rectal cancer have no remaining tumor cells after surgery.

  Recruiting at 3 sites Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei and 2 other locations · NCT06542588

• Exploring the link between imaging and tumor environment in urologic cancer

  This study looks at how CT and MRI scans relate to the tumor environment and outcomes in patients with urologic cancer to see if imaging can help predict their prognosis.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06537037

• Exploring imaging and tumor environment relationships in liver cancer

  This study is trying to see how imaging results relate to the tumor environment in liver cancer patients to better understand their outcomes.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06536998

• Evaluating PRG-1801 for treating recurrent immune thrombocytopenia

  This study is testing a new CAR-T cell therapy called PRG-1801 to see if it can safely help people with recurrent immune thrombocytopenia feel better.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei and 1 other locations · NCT06519565

• Exploring the link between imaging and tumor environment in lung cancer

  This study looks at how chest scans can help us understand the tumor environment and outcomes for people with lung cancer.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06500312

• Combining Ivonescimab with Radiation and Chemotherapy for Pancreatic Cancer

  This study is testing if combining a new drug called ivonescimab with radiation and chemotherapy can help people with pancreatic cancer feel better and improve their treatment outcomes.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan · NCT06491472

• Using multi-omics to improve diagnosis and treatment of urinary system tumors

  This study is trying to collect and analyze tumor samples from patients with bladder, kidney, and prostate cancers to see if new techniques can help improve how we diagnose and treat these tumors.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06490211

• Neoadjuvant therapy for HER2 positive locally advanced gastric cancer

  This study is testing a new treatment plan that combines radiation and medications to see if it can help people with advanced stomach cancer get ready for surgery.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06487429

• T-cell therapy for patients with advanced solid tumors

  This study is testing a new T-cell therapy for patients with advanced solid tumors, like pancreatic and lung cancer, who haven't had success with other treatments to see if it can help them.

  Recruiting at 2 sites Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei and 1 other locations · NCT06484556

• Fruquintinib and pirfenidone with an anti-PD-1 antibody in advanced colorectal cancer

  This study tests whether adding fruquintinib and pirfenidone to an anti-PD-1 therapy helps people with advanced colorectal cancer that has not responded to standard treatments.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06484153

• Using ganciclovir capsules to treat severe allergic rhinitis

  This study is testing if ganciclovir capsules can help people with severe allergic rhinitis feel better and improve their quality of life.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06436534

• Treatment of active systemic lupus erythematosus with A-319

  This study is testing a new treatment called A-319 to see if it can help people with active lupus by targeting harmful cells in their immune system.

  Recruiting at 2 sites Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei and 1 other locations · NCT06400537

• PET imaging targeting GPC3 for liver cancer diagnosis

  This study is testing a new type of PET imaging to see if it can help doctors better diagnose liver cancer in patients who might have it.

  Recruiting Early Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06383520

• Combining Cadonilimab with chemotherapy for treating advanced triple-negative breast cancer

  This study is testing if combining a new antibody treatment called Cadonilimab with chemotherapy can help people with advanced triple-negative breast cancer feel better compared to standard treatments.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06367088

• Cadonilimab plus Adriamycin for advanced soft tissue sarcoma

  This study will try cadonilimab combined with adriamycin as first-line treatment for adults under 60 with advanced soft tissue sarcoma.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06367075

• Using denosumab to treat knee osteoarthritis

  This study is testing whether denosumab, a medication usually used for osteoporosis, can help people with knee osteoarthritis feel better and slow down the disease.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06357741

• CAR-T cell therapy for severe systemic lupus erythematosus

  This study is testing a new CAR-T cell therapy to see if it can help people with severe lupus who haven't found relief from other treatments.

  Recruiting Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan · NCT06349343

• CT biomarkers for classifying and predicting bronchiectasis outcomes

  This project will test whether features seen on chest CT scans can help classify bronchiectasis and predict how adults with bronchiectasis will do over time.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06346938

• Disease progression and nutritional status in bronchiectasis

  The study will see if detailed nutritional measures (BMI, arm and calf circumference, skinfold thickness, and grip strength) relate to disease progression in adults with non-cystic fibrosis bronchiectasis.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei and 1 other locations · NCT06344000

• Evaluating Peripheral Nerve Stimulation for Postherpetic Neuralgia

  This study is testing if a new nerve stimulation treatment can help people with postherpetic neuralgia manage their pain better.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06290661

• Using stem cell exosomes to help recover from chemotherapy side effects in leukemia patients

  This study is testing if giving leukemia patients special stem cell treatments can help them recover better from the side effects of chemotherapy.

  Recruiting Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06245746

• Combination treatment for advanced liver cancer

  This study is testing a new combination of treatments for people with advanced liver cancer to see if it helps them live longer and feel better.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06244225

• Short-course radiotherapy with Fruquintinib and Adebrelimab for advanced rectal cancer

  This study is testing a new treatment plan that combines short radiation therapy with Fruquintinib and Adebrelimab for people with advanced rectal cancer to see if it helps them better than current methods.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan · NCT06234007

• Investigating the Prognostic Value of Circulating Plasma Cells in Multiple Myeloma

  This study is testing if measuring circulating plasma cells in newly diagnosed multiple myeloma patients can help predict their health outcomes and possibly replace bone marrow tests for monitoring the disease.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06228794

• Evaluating a new treatment for ultra high-risk multiple myeloma patients

  This study is testing a new treatment plan for patients with ultra high-risk multiple myeloma to see if it can help them live longer and respond better to therapy.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06140966

• CD19 CAR-T therapy for active systemic lupus erythematosus

  This study is testing a new type of treatment using CD19 CAR-T cells to see if it can help people with active systemic lupus erythematosus who aren't getting enough relief from current medications.

  Recruiting Phase 1/2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06106906

• Using CD19 Universal CAR-γδT Cells to treat active systemic lupus erythematosus

  This study is testing a new type of immune cell treatment to see if it can help people with severe systemic lupus erythematosus who aren't doing well with current therapies.

  Recruiting Phase 1/2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06106893

• Neoadjuvant treatment for ER+/HER2+ breast cancer using a combination of drugs

  This study is testing a new combination of drugs to see if it helps women with early or locally advanced HER2-positive breast cancer shrink their tumors before surgery.

  Recruiting at 2 sites Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei and 1 other locations · NCT06000917

• Exploring the link between lipid levels and organ rejection in heart transplant patients

  This study is trying to see if problems with fat levels in the blood after a heart transplant can lead to organ rejection and affect how well patients do over time.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan · NCT05994274

• Memory CD8+ T Cells and Sepsis Severity: An Observational Study at a Single Center

  This study will observe adults with sepsis to see if certain memory CD8+ T cells correlate with how severe the illness and risk of death are.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT05875740

• Improving diagnosis accuracy for small lung adenocarcinoma during surgery

  This study is testing if using different types of information during surgery can help doctors more accurately determine how invasive small lung adenocarcinomas are in patients with early-stage lung cancer.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT05830812

• Surufatinib and Serplulimab with Platinum/Etoposide for Neuroendocrine Carcinoma

  This study tests a combination of targeted therapy, immunotherapy, and chemotherapy in adults with newly treated neuroendocrine carcinoma to see if the regimen is safe and helps shrink tumors.

  Recruiting Phase 1/2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT05747729

• Combination therapy for extensive stage small cell lung cancer

  This study is testing a new combination of treatments for people with extensive stage small cell lung cancer to see if it helps them live longer and feel better than current options.

  Recruiting Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT05745350

• Research on factors affecting bronchiectasis progression

  This study looks at how different factors, like bacteria in the lungs, affect the worsening of bronchiectasis in people with this chronic lung condition.

  Recruiting at 3 sites Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Guiyang, Guizhou and 2 other locations · NCT05731427

• Impact of hsCRP on heart disease patients after PCI

  This study is trying to see if measuring a specific protein in the blood can help predict how well heart disease patients do after a procedure to open blocked arteries.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT05614050

• Treatment of relapsed/refractory acute myeloid leukemia with Anti-FLT3 CAR-T cells

  This study is testing a new CAR-T cell therapy for patients with relapsed or hard-to-treat acute myeloid leukemia to see if it can help them when other treatments have failed.

  Recruiting Phase 1 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT05445011

• Impact of Inflammation on Heart Procedure Outcomes

  This study is testing how inflammation levels in patients with coronary artery disease affect their recovery and heart health after a heart procedure.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT05131750

• Identifying biomarkers to predict resistance to neoadjuvant therapy in rectal cancer

  This study is trying to find markers in tumor samples from patients with advanced rectal cancer to see if they can predict who will not benefit from a specific treatment before it starts.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei and 1 other locations · NCT03573791

Quick answers

How many clinical trials run by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology are recruiting right now?

118, as of November 12, 2026. 4 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in China (117 trials), Taiwan (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 25, Early Phase 1: 17, Phase 1: 11, Phase 1/2: 6. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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