Prognostic model for Acute Respiratory Distress Syndrome using Electrical Impedance Tomography

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter, prospective, observational study aims to develop and validate a prognostic model for Acute Respiratory Distress Syndrome (ARDS) using Electrical Impedance Tomography (EIT). The study focuses on understanding the pathophysiological characteristics of ARDS and the causes of ventilator-induced lung injury. By revealing lung injury and heterogeneity, the model seeks to enable risk stratification and guide individualized treatment for patients with ARDS.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Meet the new 2023 ARDS global definition;
2. Age 18-80 years

Exclusion Criteria:

1. Expected death within 24 hours of screening;
2. Metastatic cancer (active malignancy with distant metastases);
3. Severe psychiatric disorders;
4. Pregnancy or postpartum status;
5. Pneumothorax or moderate to large pleural effusion without adequate drainage;
6. Chronic respiratory failure;
7. Patients with pulmonary embolism or pulmonary hypertension;
8. Heart failure patients: EF \<50% or NYHA class III or IV;
9. Patient/family refusal to participate;
10. Participation in another interventional trial within 3 months prior to enrollment

Where it's running

• Department of Critical Care Medicine, Guangdong Provincial People's Hospital
  Guangzhou, Guangdong, China Recruiting
• Department of Critical Care Medicine, Renmin Hospital of Wuhan University
  Wuhan, Hubei, China Recruiting
• Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, China Department of
  Wuhan, Hubei, China Recruiting
• Department of Emergency, Zhongshan Hospital, Fudan University
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Xiaojing Zou Zou
• Email: 249126734@qq.com
• Phone: 84+13995518630

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using Electrical Impedance Tomography to Optimize Ventilator Settings in Patients with Severe Breathing Problems

  This study is trying to see if using a special imaging technique can help set ventilators better for patients with severe breathing problems like acute respiratory failure.

  Recruiting Mahidol University · Bangkok · NCT06936618

• Understanding immune patterns and ECMO strategies to help adults with severe ARDS

  This study tests how different immune and clinical patterns in adults with moderate-to-severe ARDS respond to ECMO and lung-protective care, aiming to improve outcomes.

  Recruiting at 16 sites Southeast University, China · Beijing, Beijing Municipality and 38 other locations · NCT07726940

• Optimal corticosteroid dosing for ARDS: short vs. prolonged therapy

  This trial tests different corticosteroid doses and treatment lengths to see which helps adults with ARDS who are on ventilators.

  Recruiting Phase 4 National Taiwan University Hospital · Taipei · NCT07711964

• How different ventilator settings affect lung energy during gallbladder surgery

  This study tests whether two ventilator modes (VCV and PRVC) deliver different amounts of energy to the lungs in adults undergoing laparoscopic gallbladder removal.

  Recruiting Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · Yenimahalle, Ankara · NCT07670494

• Lateral positioning to optimize breathing in adults after abdominal surgery with ARDS

  This study tests whether lying on the left or right side helps improve lung function in adults who developed ARDS after abdominal surgery, using a bedside imaging test to watch ventilation and blood flow while changing positions.

  Recruiting Ruijin Hospital · Shanghai · NCT07669558

• Height measurement methods to guide ventilator settings in ARDS

  We’re testing whether more precise height measurements change how researchers set lung-protective tidal volumes in adults with ARDS who are on a ventilator.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07595926

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.