Low-Dose CBCT AI Model for Interventions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study compares a DeepPriorCBCT-V2 AI-assisted low-dose cone-beam CT protocol with the standard full-dose CBCT used in interventional procedures. It leverages a pre-trained neural model to preserve image quality while reducing radiation exposure. Eligible participants are adults needing CBCT-guided interventions such as cerebral angiography, lung biopsies, or liver procedures. The trial collects imaging data to assess whether the AI model maintains diagnostic and procedural adequacy at reduced radiation. Safety monitoring and informed consent are integral components of the protocol.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18 years.

  * Requires CBCT-guided interventional treatment or surgery (e.g., cerebral angiography, lung puncture biopsy, hepatic artery chemoembolization, or percutaneous liver biopsy) and meets operational indications.

    * Can understand the study's purpose, procedures, potential risks, and benefits, and voluntarily signs a written informed consent form.

Exclusion Criteria:

* History of high-dose radiation exams or treatments.

  * Known allergies or severe adverse reactions to iodine contrast agents or other relevant medications.

    * Pregnant or breastfeeding women.

      * Severe comorbidities or chronic diseases (e.g., severe diabetes, renal insufficiency).

        * Severe mental illness or cognitive impairment preventing understanding of the study procedures or providing informed consent.

          ⑥ Participants are not suitable for the trial per investigator's opinion.

Where it's running

• The First Affiliated Hospital of University of Science and Technology of China
  Hefei, Anhui, China Recruiting
• Wuhan Union Hospital
  Wuhan, Hubei, China Recruiting
• Wuhan Union Jinyin Lake Hospital
  Wuhan, Hubei, China Recruiting
• Wuhan Union West Hospital
  Wuhan, Hubei, China Recruiting
• Zhongda Hospital, Medical School, Southeast University
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Lei Chen
• Email: chan0812@126.com
• Phone: 15971480677

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.