Improving diagnosis accuracy for small lung adenocarcinoma during surgery
Improving the Intraoperative Diagnosis Accuracy for Pre-invasive and Invasive Small-sized Lung Adenocarcinoma Node by Combining Multi-modal Information
This study is testing if using different types of information during surgery can help doctors more accurately determine how invasive small lung adenocarcinomas are in patients with early-stage lung cancer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Ages | 20 Years to 80 Years |
| Sex | All |
| Sponsor | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Academic / other |
| Locations | 1 site (Wuhan, Hubei) |
| Trial ID | NCT05830812 on ClinicalTrials.gov |
What this trial studies
This observational study aims to enhance the accuracy of intraoperative diagnosis of invasiveness in small-sized lung adenocarcinoma by utilizing multi-modal information. It focuses on determining the predictive value of this information for assessing invasiveness in patients with operable clinical stage I lung cancer. The study will collect retrospective data from participants who meet specific eligibility criteria, including recent CT examinations and confirmed lung adenocarcinoma diagnoses. The findings could lead to more precise surgical decisions and better patient outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 20 to 80 with operable clinical stage I lung adenocarcinoma and tumors less than 3cm in diameter.
Not a fit: Patients with a history of preoperative treatment or those with incomplete clinical information may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes for patients with small-sized lung adenocarcinoma by enabling more accurate intraoperative diagnoses.
How similar studies have performed: While this approach is innovative, similar studies have shown promise in improving diagnostic accuracy in other cancer types, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: CT examination within 3 months before surgery Patients with operable clinical stage I lung cancer No previous treatment in the lungs or any other organ ≥ 20 years and ≤ 80 years old Tumor less than 3cm in diameter on thin-slice (0.625-1 mm) CT images Lung adenocarcinoma confirmed by surgical resection and histopathological diagnosis Exclusion Criteria: Marked artifacts on CT images History of preoperative treatment Incomplete clinical information or DICOM images History of other malignant tumors Lung cancer associated with cystic airspaces
Where this trial is running
Wuhan, Hubei
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology — Wuhan, Hubei, China (Recruiting)
Study contacts
- Principal investigator: Yang Jin, PHD — Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- Study coordinator: Xueyun Tan, MD
- Email: tanxueyun93@sina.com
- Phone: 13419692313
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.