Effects of Lung Impedance Tomography on Breathing in ARDS Patients
Physiological Effects of Lung Impedance Tomography-guided and Plat Pressure-guided Phigh During Airway Pressure Release Ventilation in Patients With Acute Respiratory Distress Syndrome
NA · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · NCT06696638
This study tests if using a special lung monitoring technique can improve breathing and blood flow in patients with acute respiratory distress syndrome by adjusting their ventilation settings.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 26 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (other) |
| Locations | 1 site (Wuhan, Hubei) |
| Trial ID | NCT06696638 on ClinicalTrials.gov |
What this trial studies
This study investigates how using lung impedance tomography (EIT) to guide pressure settings during airway pressure release ventilation (APRV) affects ventilation and blood flow in patients with acute respiratory distress syndrome (ARDS). It compares the outcomes of EIT-guided pressure settings with traditional methods, focusing on gas exchange, respiratory mechanics, and hemodynamics. The goal is to optimize treatment for ARDS patients by tailoring ventilation strategies based on real-time lung function data.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older diagnosed with ARDS according to the latest global definition.
Not a fit: Patients with severe chronic respiratory conditions or contraindications for EIT will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve respiratory function and outcomes for patients with ARDS.
How similar studies have performed: While the use of EIT in ventilation strategies is gaining interest, this specific approach is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosed with ARDS according to the 2023 global new definition of ARDS. * Age ≥ 18 years. Exclusion Criteria: * Severe chronic obstructive pulmonary disease, severe asthma, pulmonary bullae, pneumothorax, subcutaneous emphysema, mediastinal emphysema, etc. · Contraindications for EIT, such as chest wound dressing, pacemaker implantation, defibrillator use, etc. * Pulmonary interstitial disease. * Uncorrected shock of various types. * Intracranial hypertension. * Pregnant and postpartum women.
Where this trial is running
Wuhan, Hubei
- Wuhan Union hospital — Wuhan, Hubei, China (RECRUITING)
Study contacts
- Study coordinator: jing Xiao Zou
- Email: 249126734@qq.com
- Phone: +862785351606
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: ARDS: Acute Respiratory Distress Syndrome, ARDS, APRV, EIT, Phigh