Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using deep learning reconstruction for ankle MRI images

Official title: Clinical Value of Deep Learning Reconstruction Technology in Ankle MRI

Run by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · NCT07274423 · Data updated 2026-11-12

We will try AI-based MRI scanning for adults with ankle injuries to see if it gives clearer diagnostic images than standard MRI.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment120 (estimated)
SponsorUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology
Academic / other
Locations1 site (Wuhan, Hubei)
StatusRecruiting
StartedAugust 1, 2025
Main results expectedAugust 1, 2026
Study endsAugust 1, 2026
Registry record updatedDecember 10, 2025
Trial IDNCT07274423 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults over 18 with a clear history of ankle trauma who need an ankle MRI at Wuhan Union Hospital and can provide informed consent are ideal candidates.

Probably not a fit

Patients with MRI contraindications, prior ankle surgery, or those who cannot complete the MRI or yield diagnostically usable images are unlikely to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults who undergo ankle MRI at Wuhan Union Hospital from August 2025 to August 2026 will be randomly allocated to receive either AI-based deep learning reconstruction MRI sequences or conventional non-AI MRI sequences. Image sets will be compared for objective image quality metrics and diagnostic usability by radiologists. Patients with MRI contraindications, prior ankle surgery, or incomplete scans will be excluded. The protocol focuses on imaging acquisition and reconstruction rather than therapeutic interventions.

Why it matters

Potential benefit: If successful, this could produce clearer ankle MRI images that help radiologists make more accurate diagnoses.

How similar studies have gone: Related deep-learning reconstruction work has improved MRI image quality in other body areas, though its specific application to ankle trauma imaging is less extensively reported.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients undergoing ankle MRI at Wuhan Union Hospital from August 2025 to August 2026;
2. Aged \> 18 years old;
3. Patients who agree to participate in the study and provide signed informed consent;
4. Presence of a clear history of ankle trauma and related symptoms requiring MRI for diagnosis or evaluation.

Exclusion Criteria:

1 .Patients with MR examination contraindications (e.g., implanted metal devices or severe claustrophobia); 2. Patients with prior ankle surgery; 3. Patients who failed to complete MR examination or whose image quality was insufficient for diagnostic purposes.

Where it's running

  • Union Hospital,Tongji Medical College,Huazhong University of Science and Technology
    Wuhan, Hubei, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.