Using deep learning reconstruction for ankle MRI images
Clinical Value of Deep Learning Reconstruction Technology in Ankle MRI
We will try AI-based MRI scanning for adults with ankle injuries to see if it gives clearer diagnostic images than standard MRI.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Academic / other |
| Locations | 1 site (Wuhan, Hubei) |
| Trial ID | NCT07274423 on ClinicalTrials.gov |
What this trial studies
Adults who undergo ankle MRI at Wuhan Union Hospital from August 2025 to August 2026 will be randomly allocated to receive either AI-based deep learning reconstruction MRI sequences or conventional non-AI MRI sequences. Image sets will be compared for objective image quality metrics and diagnostic usability by radiologists. Patients with MRI contraindications, prior ankle surgery, or incomplete scans will be excluded. The protocol focuses on imaging acquisition and reconstruction rather than therapeutic interventions.
Who should consider this trial
Good fit: Adults over 18 with a clear history of ankle trauma who need an ankle MRI at Wuhan Union Hospital and can provide informed consent are ideal candidates.
Not a fit: Patients with MRI contraindications, prior ankle surgery, or those who cannot complete the MRI or yield diagnostically usable images are unlikely to benefit.
Why it matters
Potential benefit: If successful, this could produce clearer ankle MRI images that help radiologists make more accurate diagnoses.
How similar studies have performed: Related deep-learning reconstruction work has improved MRI image quality in other body areas, though its specific application to ankle trauma imaging is less extensively reported.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients undergoing ankle MRI at Wuhan Union Hospital from August 2025 to August 2026; 2. Aged \> 18 years old; 3. Patients who agree to participate in the study and provide signed informed consent; 4. Presence of a clear history of ankle trauma and related symptoms requiring MRI for diagnosis or evaluation. Exclusion Criteria: 1 .Patients with MR examination contraindications (e.g., implanted metal devices or severe claustrophobia); 2. Patients with prior ankle surgery; 3. Patients who failed to complete MR examination or whose image quality was insufficient for diagnostic purposes.
Where this trial is running
Wuhan, Hubei
- Union Hospital，Tongji Medical College，Huazhong University of Science and Technology — Wuhan, Hubei, China (Recruiting)
Study contacts
- Study coordinator: Lian Yang
- Email: yanglian@hust.edu.cn
- Phone: 18986273791
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.