Clinical trial Recruiting at 1 site Observational Ages 18 and up

AI-based body composition mapping from CT scans to predict outcomes after TACE for liver cancer

Official title: Deep Learning-Based Multidimensional Body Composition Mapping for Predicting Clinical Outcomes in Hepatocellular Carcinoma Patients Undergoing TACE

Run by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · NCT07235410 · Data updated 2026-11-12

This project will test whether an AI that analyzes routine CT scans can help predict survival and treatment response for adults with hepatocellular carcinoma who receive TACE.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology
Academic / other
Locations1 site (Wuhan, Hubei)
StatusRecruiting
StartedNovember 1, 2025
Main results expectedDecember 31, 2025
Study endsNovember 1, 2026
Registry record updatedNovember 19, 2025
Trial IDNCT07235410 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults (over 18) with hepatocellular carcinoma who underwent TACE and have good-quality pre-treatment CT scans and complete medical records.

Probably not a fit

Patients without usable CT images, with other active cancers, incomplete records, or who did not receive TACE would likely not benefit from this model.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center observational project uses deep learning to automatically analyze pre-treatment CT scans from adult HCC patients who underwent transarterial chemoembolization (TACE) between January 1, 2018 and May 31, 2024. The algorithm will quantify multidimensional body composition features such as organ sizes and muscle/fat condition across the abdomen and link these imaging features with clinical records. Patients with poor image quality, other active malignancies, loss to follow-up, or incomplete records will be excluded. The resulting model aims to predict survival and treatment outcomes after TACE to support more personalized treatment decisions.

Why it matters

Potential benefit: If successful, the tool could help doctors personalize TACE decisions by identifying patients most likely to benefit and those at higher risk of poor outcomes.

How similar studies have gone: Related radiomics and machine-learning approaches in liver cancer and other oncology settings have shown promising predictive signals, but deep-learning body composition mapping requires further validation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients diagnosed with "Hepatocellular Carcinoma" from January 1, 2018 to May 31, 2024;
2. Age \> 18 years old.

Exclusion Criteria:

1. Poor image quality;
2. Loss of follow-up;
3. Presence of another type of malignant tumor other than liver cancer;
4. Incomplete medical records.

Where it's running

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
    Wuhan, Hubei, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.