Research on factors affecting bronchiectasis progression

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the mechanisms influencing the progression of bronchiectasis, a chronic respiratory condition characterized by irreversible bronchial dilation. It aims to analyze the relationship between airway microbiota, particularly Pseudomonas aeruginosa colonization, and disease severity. The study will collect demographic data, lung function tests, and biological samples, including sputum, stool, and peripheral blood, to assess inflammatory markers and microbiota composition. The findings may help in understanding the heterogeneity of bronchiectasis and its clinical implications.

Why it matters

Who can join: the full rules

Inclusion criteria:

* 18 years or older
* Bronchiectasis confirmed by high-resolution computed tomographic scan(HRCT)
* Chronic expectoration with ability to provide a sputum sample at the study visit
* Provision of written informed consent

Exclusion criteria:

* Traction bronchiectasis
* Lack of important clinical information

Where it's running

• Guizhou Provincial people's Hospital
  Guiyang, Guizhou, China Recruiting
• Wuhan Union Hospital
  Wuhan, Hubei, China Recruiting
• Department of Respiratory and Critical Care Medicine, Yichang Central People's Hospital
  Yichang, Hubei, China Recruiting

Study contacts

• Principal investigator: Xiaorong Wang — Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
• Study coordinator: Xiaorong Wang
• Email: rong-100@163.com
• Phone: 18627195231

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.