Sponsor or institution
Clinical trials and research at China National Center for Cardiovascular Diseases
As of November 12, 2026, Find a Trial lists 64 clinical trials run by China National Center for Cardiovascular Diseases that are recruiting, at sites in 2 countries (most in China (64), United States (1)). 1 was first registered in the last 30 days. By phase: Phase 4 (10), Phase 1 (1), Phase 2 (1), Early Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 64Clinical trials
- 1New in 30 days
- 2Countries
Newest trials
All recruiting trials (64)
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Conscious Sedation vs General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial Fibrillation
This trial tests whether local anesthesia with conscious sedation can match general anesthesia for pulsed field ablation in adults with paroxysmal atrial fibrillation.
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Biomarkers to predict CSA-AKI risk before heart surgery
This study tests new biomarkers to see if they can predict CSA-AKI risk in adults undergoing cardiovascular surgery.
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Safety and Efficacy of an Extracorporeal Ventricular Assist System for Cardiogenic Shock
This study tests whether an extracorporeal ventricular assist device can safely provide short-term heart support and help patients with cardiogenic shock or trouble weaning from bypass.
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QFR-Guided Heart Revascularization Quality Registry in CAD
This registry tests whether using quantitative flow ratio (QFR) to guide coronary revascularization decisions across many centers can standardize quality in patients with coronary artery disease.
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Perioperative GFR Monitoring to Predict CSA-AKI and CA-AKI
This study tests whether perioperative transcutaneous fluorescence GFR measurements can predict CSA-AKI or CA-AKI in adults undergoing cardiovascular procedures or iodine contrast exposure.
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Transcatheter repair for atrial functional mitral regurgitation in high-risk patients
This trial tests whether adding a catheter-based mitral valve repair (TEER) to optimized medical therapy helps adults with atrial functional MR who are at high surgical risk.
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Vasoactive Agents in Pulmonary Hypertension Crisis
This trial tests whether dopamine, norepinephrine, or epinephrine can safely and effectively help people with a pulmonary hypertension crisis who are in the hospital.
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Mobile-based home cardiac rehab to see if it reduces non-calcified coronary plaque
A mobile, at-home cardiac rehabilitation program is being tested to see if it can reduce non-calcified plaque in people with mild to moderate coronary artery narrowing.
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Mazdutide and coronary plaque in people with coronary artery disease and overweight or obesity
This study tests whether mazdutide can slow or reduce coronary plaque build-up in adults with coronary artery disease who are overweight or obese.
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QFR-guided virtual stenting to optimize PCI before the procedure
We’re testing whether using QFR-based virtual stenting before PCI can improve heart-procedure outcomes compared with standard angiography planning in adults with coronary artery disease.
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Personalized Atrial Fibrillation Ablation Using Unipolar QS-Potential Mapping
In people with atrial fibrillation who are having catheter ablation, this study tests whether guiding the procedure with unipolar QS-potential mapping can improve outcomes compared with standard pulmonary vein isolation.
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Pulsed Field Ablation Outcomes in Atrial Fibrillation: Randomized Comparison to Traditional Ablation
This study tests pulsed field ablation versus conventional radiofrequency ablation in adults with atrial fibrillation to see which method better preserves heart rhythm.
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Surgical techniques and outcomes across the lifespan in congenital heart disease in China
See which surgical factors and care patterns affect recovery after heart surgery for people with complex congenital heart disease in China.
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IVUS-based ultrasound method to measure blood flow through narrowed coronary arteries
This study tests whether an IVUS-derived software can quickly tell if a narrowed coronary artery is reducing blood flow in adults having coronary angiography, without using pressure wires or vasodilator drugs.
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Low-dose Colchicine after TAVR to help prevent valve clots
This study tests whether taking a low dose of colchicine for 12 months after transcatheter aortic valve replacement can reduce valve thrombosis compared with standard care alone.
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Exercise-prescription mini-program for people with high blood pressure, high blood sugar, high cholesterol, or high uric acid.
This study will try a digital exercise-prescription mini-program to help adults with one or more of the 'Four Highs' increase physical activity and improve related health measures over six months in primary care.
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Ademetionine treatment for obstructive hypertrophic cardiomyopathy
This study will test whether taking ademetionine can improve exercise capacity, symptoms, heart structure and quality of life in adults with obstructive hypertrophic cardiomyopathy.
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Aortic no-touch versus partial aortic clamping for off-pump coronary bypass
This trial will test whether an aortic no-touch technique reduces silent brain infarctions compared with partial aortic clamping in adults having off-pump coronary artery bypass surgery.
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AI facial-photo screening for coronary artery disease in high-risk community members
This project tests whether an AI algorithm can use a facial photo to screen for coronary artery disease in people with diabetes, high blood pressure, or over age 65.
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AI-guided exercise and recovery program for people with coronary heart disease
This project will see if a smartphone AI program combined with a wristband helps adults with coronary heart disease do home exercise after leaving the hospital and improves their fitness and heart-risk measures.
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One-month vessel healing after BioFreedom polymer-free drug-coated stent versus Xience drug-eluting stent in heart attack patients with high bleeding risk
We'll use very detailed optical imaging to see if the polymer-free BioFreedom stent leads to faster or better vessel healing than the Xience stent in people with a recent heart attack who are at high bleeding risk.
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Three-year follow-up after pCAD-POAF
This study follows people who were in the pCAD-POAF trial to see how they’re doing three years after their surgery.
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Long-term follow-up of the Corheart 6 left ventricular assist pump for advanced heart failure
This project will test whether the Corheart 6 heart pump is safe and provides durable support for adults with advanced left heart failure who received the device on or after October 2021.
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Adding Compound Danshen and Qishen Yiqi pills for older adults with ongoing angina after standard heart treatment
This study will test whether adding two traditional Chinese medicine pills (Compound Danshen Dripping Pill and Qishen Yiqi Dripping Pill) helps people aged 75–89 who still have angina after standard medical treatment.
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AI-guided post-discharge care for premature coronary artery disease
This trial will test whether an AI-powered app and stratified management system can lower deaths, heart attacks, strokes, and rehospitalizations and improve risk-factor control in adults aged 18–45 with premature coronary artery disease.
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Predicting future heart problems in young adults with premature coronary artery disease (MAP-CHD)
This project will follow Chinese adults under 45 with premature coronary artery disease to see if clinical features and blood tests can predict future adverse heart events.
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Comparing new metformin sustained-release tablets to regular metformin in patients with type 2 diabetes and coronary heart disease
This study is testing if a new type of metformin tablet helps people with type 2 diabetes and heart disease manage their blood sugar better than the regular metformin.
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Sacubitril/valsartan after bypass to treat moderate ischemic mitral regurgitation
This trial will test whether the drug sacubitril/valsartan can reduce moderate ischemic mitral regurgitation in people with coronary artery disease who have had isolated coronary artery bypass grafting (CABG).
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Three-vessel ultrasonic flow ratio to predict one-year heart risk in people with coronary artery disease
This will test if measuring the ultrasonic flow ratio in all three coronary arteries can help predict one-year risk of major heart problems in adults with coronary artery disease who have at least 30% narrowing in each artery.
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Non‑drug, non‑invasive treatments given before heart surgery to protect the brain
This trial will test whether remote ischemic preconditioning (RIPC) and transcranial electrical stimulation (tDCS) given before elective heart surgery can reduce stroke, delirium, and other brain complications in adults at high risk.
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Comparing self-expandable and balloon-expandable valves for aortic dilation treatment
This study is testing whether self-expandable or balloon-expandable valves work better for people with aortic dilation who are getting a heart valve replacement.
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AI analysis of surgeons' techniques during coronary artery bypass grafting
We will see if an AI program can score surgeons' stitching technique during left anterior descending artery bypass in adults having their first isolated CABG.
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Assessing brain function during cardiac surgery
This study is trying to find out what factors might lead to brain problems after heart surgery by checking patients' brain function before, during, and after the operation.
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AI 'Smart Family Doctor' support for people after CABG or PCI
We will test whether an AI-assisted smartphone 'Smart Family Doctor' program helps adults after coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) better control blood pressure, blood sugar, and cholesterol.
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Discontinuing blood thinners after successful catheter ablation for atrial fibrillation
This study tests whether stopping anticoagulation after a successful AF ablation is safe for patients who have had no recurrence within a year.
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Treatment for gum disease to slow heart valve narrowing
This study is testing if treating gum disease can help slow down the worsening of heart valve narrowing in adults who have both aortic valve stenosis and gum issues.
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Using empagliflozin to treat pulmonary arterial hypertension
This study is testing if a medication called empagliflozin can help people with pulmonary arterial hypertension feel better by lowering their blood pressure in the lungs and improving heart function.
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Modified procedure for enlarging the aortic root in patients with small aortic annulus
This study is testing a new way to enlarge the aortic root in people aged 50-70 with severe aortic stenosis and a small aortic annulus to see if it works better than the standard valve replacement method.
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Observing heart changes in patients with Fabry disease
This study looks at heart changes in people with Fabry disease to better understand how the condition affects their heart health.
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Potts-shunt procedure for children with severe pulmonary hypertension
This study tests if adding the Potts-shunt procedure to standard drug treatment can help children with severe pulmonary hypertension feel better compared to just using the medication alone.
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Xuesaitong soft capsules to lower inflammation and improve risk markers in people with coronary heart disease
This trial tests whether Xuesaitong soft capsules lower hsCRP and improve other cardiovascular risk markers in adults with stable coronary heart disease who are already on statins and antiplatelet therapy.
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Investigating cerebral microembolization in patients with PFO closure
This study is trying to see if patients with a heart condition called PFO who undergo a closure procedure experience tiny blood clots in the brain and how these might relate to existing clots in the heart.
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Monitoring lifestyle and physical fitness in China's working population
This study is tracking the health and lifestyle habits of working people in China to see how these factors affect heart health over time.
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Comparing low-dose and standard-dose rivaroxaban for elderly patients with atrial fibrillation
This study is testing whether a lower dose of rivaroxaban works just as well as the standard dose for older adults with atrial fibrillation to prevent strokes and heart problems while reducing side effects.
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Early Initiation of PCSK9 Inhibitor Tafolecimab in ACS Patients Undergoing PCI
This trial tests starting Tafolecimab early in people with acute coronary syndrome who are having PCI to lower bad cholesterol quickly and see if it reduces heart problems after discharge.
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Effects of a medication on heart health in patients with high blood pressure
This study is testing if a heart medication called empagliflozin can improve heart health in people with high blood pressure who are at risk for heart failure but don’t have diabetes.
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Exploring coronary artery disease progression using radial wall strain
This study is testing if a new way to measure heart artery strain can help predict how quickly heart disease gets worse in people who recently had a heart attack.
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Comparing LAA clipping to NOACs for stroke prevention in atrial fibrillation
This study is testing if a procedure called LAA clipping can prevent strokes better than blood thinners in people with long-term atrial fibrillation who are at high risk for blood clots.
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24-month versus 12-month dual antiplatelet therapy after drug-eluting stent in people with high Lipoprotein(a)
This trial will test whether continuing dual antiplatelet therapy for 24 months instead of 12 months lowers the risk of death, heart attack, or stroke in people with high Lipoprotein(a) who had a drug-eluting stent and were event-free at one year.
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Comparing blood-thinning treatments after heart surgery
This study is testing if adding a blood thinner called warfarin to standard treatment can help heart surgery patients recover better and avoid problems with their grafts.
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Lowering LDL cholesterol in older patients with heart disease
This study is testing whether aiming for lower or higher LDL cholesterol levels can help older patients with heart disease stay healthier and avoid serious heart problems.
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Assessing changes in aortic diameter after valve replacement
This study looks at how the size of the aorta changes after patients have a heart valve replacement to see if it gets bigger or stays the same, especially for those who already had a larger aorta.
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FAST-guided PCI in STEMI with Multivessel Disease
This trial tests whether using the FAST technique during PCI in STEMI patients with multivessel disease improves outcomes compared with standard treatment.
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Guiding NOAC therapy for patients with acute coronary syndrome after heart procedures
This study is testing a new combination of heart medications to see if it can help people with acute coronary syndrome avoid serious heart problems without causing more bleeding than standard treatment.
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Comparing hybrid and catheter ablation for atrial fibrillation in patients with hypertrophic cardiomyopathy
This study is testing whether a new hybrid ablation method works better than traditional catheter ablation for controlling heart rhythm in patients with hypertrophic cardiomyopathy and ongoing atrial fibrillation.
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National registry of rapid unexplained coronary in‑stent restenosis (RECUR)
This nationwide registry will collect clinical and test data to see if patterns or biomarkers link to rapid unexplained in‑stent restenosis in adults with coronary stents.
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Monitoring the safety of targeted drugs for pulmonary hypertension using a computerized system
This study is trying to see how safe targeted drugs are for people with pulmonary hypertension by following at least 700 patients over time using a computerized system.
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Investigating the internal structure of patent foramen ovale related to stroke and migraine
This study is trying to learn more about the tiny structures of a heart condition called patent foramen ovale (PFO) in people who have had a stroke, a mini-stroke, or migraines, to see if closing it helps and to understand the risks better.
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Investigating surgical techniques to reduce stroke risk during heart surgery
This study is testing whether certain surgical techniques during heart surgery can help reduce the risk of stroke and new heart rhythm problems in patients having bypass surgery.
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Evaluating treatment quality for adults with heart attacks in China
This study is trying to see how well hospitals in China are treating adults who have heart attacks to help improve their care and outcomes.
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Registry for inherited ventricular arrhythmias in China
This study is trying to understand how genetic factors affect dangerous heart rhythm problems in people with inherited conditions like Brugada syndrome and Long QT syndrome by collecting health information from 500 participants across China.
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Registry for patients with structural ventricular arrhythmias in China
This study is trying to find out how common serious heart rhythm problems are in China and what factors might increase the risk for people with these conditions by collecting health information from 2000 participants.
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Registry for a rare type of pulmonary hypertension
This study is setting up a national registry to collect information about people with a rare type of pulmonary hypertension to better understand the condition and its causes.
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Observational study on hypertrophic cardiomyopathy in Chinese patients
This study is trying to understand hypertrophic cardiomyopathy in Chinese patients by collecting health information and samples to see how genetics and other factors play a role in the condition and its risks.
Quick answers
How many clinical trials run by China National Center for Cardiovascular Diseases are recruiting right now?
64, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in China (64 trials), United States (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 10, Phase 1: 1, Phase 2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.