Clinical trial Recruiting at 1 site Interventional Ages 18 and up

AI-guided exercise and recovery program for people with coronary heart disease

Official title: Artificial Intelligence-enhanced Stratified Management Platform Guiding Home-based Exercise Rehabilitation for Coronary Heart Disease Patients: a Randomized Control Trial

Run by China National Center for Cardiovascular Diseases · NCT07259278 · Data updated 2026-11-12

This project will see if a smartphone AI program combined with a wristband helps adults with coronary heart disease do home exercise after leaving the hospital and improves their fitness and heart-risk measures.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorChina National Center for Cardiovascular Diseases
Government
Locations1 site (Beijing, Beijing Municipality)
StatusRecruiting
StartedDecember 1, 2025
Main results expectedNovember 30, 2026
Study endsNovember 30, 2026
Registry record updatedDecember 2, 2025
Trial IDNCT07259278 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults over 18 with coronary heart disease who are judged low-risk for exercise by the GRACE score, can use a smartphone (or have a caregiver who can), and are willing to provide informed consent are ideal candidates.

Probably not a fit

Patients with recent myocardial infarction, planned revascularization, significant left main or major vessel stenosis, severe cognitive or exercise impairment, advanced malignancy, multi-organ failure, or life expectancy under three months are unlikely to benefit or to be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with coronary heart disease who are classified as low exercise risk will be assigned to either an AI-enabled stratified management platform used with a sports wristband or to routine post-discharge care and followed for three months. The AI platform provides personalized exercise prescriptions, remote monitoring via the wristband, motivational support, and tailored risk-factor management through a smartphone app. The primary outcome is change in peak oxygen consumption (VO2peak) at 3 months, with secondary outcomes including daily physical activity, exercise adherence and motivation, control of modifiable cardiovascular risk factors, and safety of home-based exercise. Baseline and follow-up visits occur at Fuwai Hospital with ongoing remote data collection through the app and wearable.

Why it matters

Potential benefit: If successful, the platform could help patients increase exercise capacity, improve adherence to home rehabilitation, and better control cardiovascular risk factors.

How similar studies have gone: Previous telerehabilitation and digital cardiac rehabilitation programs have improved adherence and exercise capacity, but AI-driven stratified management platforms are relatively novel and less extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* CHD patients aged over 18 years;
* Stratified as low-risk for cardiovascular events during exercise and classified as low-risk according to the GRACE risk score.
* Ability of the patient or close relatives to use smartphones and applications;
* Willingness to participate and sign the informed consent form.

Exclusion Criteria:

* Residual stenosis of \>50% in the left main coronary artery, or \>70% stenosis in other major epicardial vessels;
* Planned coronary revascularization within the next 3 months;
* Acute myocardial infarction within the past 1 month;
* Severe cognitive impairment;
* Severely impaired exercise capacity.
* Advanced-stage malignancy;
* Life expectancy less than 3 months;
* Severe multi-organ failure;
* Other conditions deemed unsuitable for home-based exercise rehabilitation following assessment by a specialist rehabilitation physician.
* Refusal to provide written informed consent.

Where it's running

  • Fuwai Hospital, Chinese Academy of Medical Sciences/National Center for Cardiovascular Diseases
    Beijing, Beijing Municipality, China
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.