National registry of rapid unexplained coronary in‑stent restenosis (RECUR)

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a national, multicenter observational cohort registry enrolling adults with rapid recurrences of unexplained coronary in‑stent restenosis (RECUR). Participating centers will collect standardized clinical data, imaging, laboratory biomarkers, treatment details, and follow‑up outcomes while patients receive usual care from experienced clinicians. The project aims to build a diagnostic assessment framework and enable longitudinal analyses to identify patterns, risk factors, and potential biomarkers associated with rapid unexplained restenosis. Data will be centrally managed and analyzed to inform diagnostic criteria and guide future interventional research.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥ 18 years;
2. Patients meeting the diagnostic criteria for Rapid rEcurrences of Coronary Unexplained in-stent Restenosis (RECUR);
3. Patients fully informed about the trial procedures who provide written informed consent.

Exclusion Criteria:

1. Patients presenting with any of the following:

   * Other severe comorbidities (e.g., malignant tumors, heart failure) with a life expectancy \<12 months;

     * Known autoimmune/rheumatic diseases including systemic lupus erythematosus, Takayasu arteritis, Behçet's disease, polyarteritis nodosa, Wegener granulomatosis (granulomatosis with polyangiitis), eosinophilic arteritis, giant cell arteritis, rheumatoid arthritis, or IgG4-related disease;

       * Variant angina (Prinzmetal's angina);

         * Coronary artery dissection;

           * Thrombophilia;

             * Stent underexpansion.
2. Presence of psychiatric disorders;
3. Known inability to complete expected study follow-up for any reason;
4. Patients deemed ineligible for enrollment by the investigator.

Where it's running

• Jia Lei
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Hong Jian Wang, Dr.
• Email: hongjian.wang@gmail.com
• Phone: 008613910008985

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.