Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Investigating surgical techniques to reduce stroke risk during heart surgery

Official title: Fuwai Hospital, Chinese Academy of Medical Science

Run by China National Center for Cardiovascular Diseases · NCT04220047 · Data updated 2026-11-12

This study is testing whether certain surgical techniques during heart surgery can help reduce the risk of stroke and new heart rhythm problems in patients having bypass surgery.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment400 (estimated)
SponsorChina National Center for Cardiovascular Diseases
Government
Locations1 site (Beijing)
StatusRecruiting
StartedApril 30, 2020
Main results expectedDecember 31, 2021
Study endsDecember 31, 2026
Registry record updatedJanuary 20, 2021
Trial IDNCT04220047 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients scheduled for their first isolated off-pump coronary artery bypass surgery.

Probably not a fit

Patients with a history of atrial fibrillation or those requiring concurrent surgeries may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of left atrial appendage resection and Marshall ligament amputation on clinical outcomes in patients undergoing off-pump coronary artery bypass surgery. It aims to determine whether these surgical interventions can reduce the incidence of new-onset atrial fibrillation and subsequent stroke risk. The study focuses on patients who are undergoing isolated first off-pump coronary artery bypass, excluding those with a history of atrial fibrillation or other significant health issues. By analyzing postoperative outcomes, the research seeks to provide insights into optimizing surgical techniques for better patient outcomes.

Why it matters

Potential benefit: If successful, this study could significantly lower the risk of stroke and atrial fibrillation in patients undergoing heart surgery.

How similar studies have gone: While there is some evidence suggesting the benefits of similar surgical approaches, this specific combination of techniques is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* isolated first off-pump coronary artery bypass

Exclusion Criteria:

* Preoperative atrial fibrillation or a history of atrial fibrillation;
* Concurrent cardiac or non-cardiac surgery
* Intraoperative convert to bypass bypass surgery
* Emergency surgery
* History of previous cardiac surgery
* Severe organ dysfunction

Where it's running

  • Fuwai Hospital
    Beijing, China
    Recruiting

Study contacts

  • Principal investigator: Hansong Sun, doctor — Chinese Academy of Medical Sciences, Fuwai Hospital
  • Study coordinator: Hengchao Wu, doctor
  • Email: whcwuhengchao@163.com
  • Phone: 010-88322355

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.