Investigating surgical techniques to reduce stroke risk during heart surgery
Fuwai Hospital, Chinese Academy of Medical Science
This study is testing whether certain surgical techniques during heart surgery can help reduce the risk of stroke and new heart rhythm problems in patients having bypass surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 400 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | China National Center for Cardiovascular Diseases Government |
| Locations | 1 site (Beijing) |
| Trial ID | NCT04220047 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of left atrial appendage resection and Marshall ligament amputation on clinical outcomes in patients undergoing off-pump coronary artery bypass surgery. It aims to determine whether these surgical interventions can reduce the incidence of new-onset atrial fibrillation and subsequent stroke risk. The study focuses on patients who are undergoing isolated first off-pump coronary artery bypass, excluding those with a history of atrial fibrillation or other significant health issues. By analyzing postoperative outcomes, the research seeks to provide insights into optimizing surgical techniques for better patient outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are patients scheduled for their first isolated off-pump coronary artery bypass surgery.
Not a fit: Patients with a history of atrial fibrillation or those requiring concurrent surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly lower the risk of stroke and atrial fibrillation in patients undergoing heart surgery.
How similar studies have performed: While there is some evidence suggesting the benefits of similar surgical approaches, this specific combination of techniques is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * isolated first off-pump coronary artery bypass Exclusion Criteria: * Preoperative atrial fibrillation or a history of atrial fibrillation; * Concurrent cardiac or non-cardiac surgery * Intraoperative convert to bypass bypass surgery * Emergency surgery * History of previous cardiac surgery * Severe organ dysfunction
Where this trial is running
Beijing
- Fuwai Hospital — Beijing, China (Recruiting)
Study contacts
- Principal investigator: Hansong Sun, doctor — Chinese Academy of Medical Sciences, Fuwai Hospital
- Study coordinator: Hengchao Wu, doctor
- Email: whcwuhengchao@163.com
- Phone: 010-88322355
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.