AI facial-photo screening for coronary artery disease in high-risk community members

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will use an AI algorithm to analyze standardized facial images from community-dwelling adults at high risk for coronary artery disease (those with diabetes, hypertension, or aged >65). Participants without prior CAD or heart failure will have facial photographs taken and their AI-assigned risk will be compared to actual CAD prevalence in high- versus low-risk groups. The study will also compare the CAD detection rate using the AI screening strategy to the natural detection rate observed in the real-world cohort. Enrollment and data collection occur at participating hospitals in Zhoukou, Henan and at Fuwai Hospital/CAMS in Beijing.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \>= 18 years.
* Community high-risk population, defined as individuals meeting at least one of the following criteria:

  1. Diagnosed with Diabetes Mellitus;
  2. Diagnosed with Hypertension;
  3. Advanced age (\> 65 years old).

Exclusion Criteria:

* Prior confirmed diagnosis of Coronary Heart Disease (CAD), including clinically diagnosed CAD, history of Coronary Artery Bypass Grafting (CABG), or history of Percutaneous Coronary Intervention (PCI).
* History of diagnosed Heart Failure.
* Significant facial alterations or conditions that may interfere with AI image analysis, such as plastic surgery, severe facial trauma, or heavy makeup.
* Refusal to participate in the study.

Where it's running

• Zhoukou Chuanhui District Hospital of Traditional Chinese Medicine
  Zhoukou, Henan, China Recruiting
• Zhoukou Specialized Disease Hospital
  Zhoukou, Henan, China Recruiting
• Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
  Beijing, China Not yet recruiting

Study contacts

• Study coordinator: zhe zheng, MD, PhD
• Email: zhengzhe@fuwai.com
• Phone: +86-010-88398027

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.