Observational study on hypertrophic cardiomyopathy in Chinese patients
Official title: The Chinese Hypertrophic Cardiomyopathy Study(CHCS)
Run by China National Center for Cardiovascular Diseases · NCT02696135 · Data updated 2026-11-12
This study is trying to understand hypertrophic cardiomyopathy in Chinese patients by collecting health information and samples to see how genetics and other factors play a role in the condition and its risks.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 3000 (estimated) |
| Sponsor | China National Center for Cardiovascular Diseases Government |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | March 23, 2011 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2028 |
| Registry record updated | March 27, 2018 |
| Trial ID | NCT02696135 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients diagnosed with hypertrophic cardiomyopathy characterized by significant left ventricle wall thickness.
✕Probably not a fit
Patients with other cardiac or systemic diseases that cause similar cardiac hypertrophy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on hypertrophic cardiomyopathy (HCM), a common inherited cardiac condition, by recruiting patients to collect comprehensive clinical data and biological specimens. It aims to explore the genetic and molecular underpinnings of HCM through multi-omics screening, which includes genomics, epigenomics, transcriptomics, proteomics, and metabolomics. Additionally, the study will evaluate the effectiveness of existing sudden cardiac death risk stratification guidelines in the Chinese population and identify novel risk factors and predictive models tailored for these patients.
Why it matters
Potential benefit: If successful, this study could lead to improved risk stratification and personalized treatment strategies for patients with hypertrophic cardiomyopathy.
How similar studies have gone: While studies on hypertrophic cardiomyopathy exist, this approach utilizing multi-omics and focusing on the Chinese population is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: Patients with HCM diagnosed by observation of unexplained maximal left ventricle wall thickness ≥15 mm on echocardiography and/or cardiac magnetic resonance imaging or or ≥13 mm for individuals with family history of HCM. Exclusion criteria: Individuals with other cardiac or systemic diseases capable of producing that magnitude of cardiac hypertrophy.
Where it's running
-
Fuwai hospital
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Principal investigator: Song Lei, MD.&ph.D — Chinese Academy of Medical Sciences, Fuwai Hospital
- Study coordinator: Song Lei, MD.&ph.D
- Email: clinicalfw@163.com
- Phone: 86-13810532620
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.