Condition

Uveitis clinical trials and research

• 10Clinical trials
• 45NIH research projects
• 1New in 30 days
• 24Countries

Newest Uveitis clinical trials

All recruiting trials (10)

• Ocular Fluid Work-up in Presumed Trematode-Induced Granulomatous Uveitis

  This study tests ocular fluid samples from patients with presumed trematode-induced granulomatous uveitis who are having eye surgery to look for clues about the cause.

  Recruiting Kasr El Aini Hospital · Cairo, Giza Governorate · NCT07885137

• PANDA-ASOCT: Detecting Uveitis in Children with Automated Eye Image Analysis

  This study tests a high-speed, non-invasive eye imaging system with automated analysis to help detect uveitis in children and young people who attend a clinic for uveitis or juvenile idiopathic arthritis.

  Recruiting Sheffield Children's NHS Foundation Trust · Sheffield, South Yorkshire · NCT07813598

• GenSci048 vs placebo in active non-infectious uveitis

  This study tests whether GenSci048 can help people with active non-infectious uveitis compared with placebo.

  Recruiting Phase 2 Changchun GeneScience Pharmaceutical Co., Ltd. · Shanghai, Shanghai Municipality · NCT07547995

• Uveitis in children under 18

  This project collects medical information from children with uveitis to see how often different types occur and what treatments and clinical features look like.

  Recruiting at 4 sites Jaeb Center for Health Research · Boston, Massachusetts and 3 other locations · NCT07518134

• Metagenomic testing for infections in people with eye inflammation

  This project will test metagenomic sequencing on eye fluid to find infections in adults with unexplained ocular inflammation who are at risk of vision loss.

  Recruiting Moorfields Eye Hospital NHS Foundation Trust · London · NCT06974162

• Observational study on chronic uveitis in children

  This study is trying to gather information about chronic uveitis in children to improve how doctors diagnose and treat this rare eye condition.

  Recruiting at 10 sites Meyer Children's Hospital IRCCS · Kansas City, Kansas and 18 other locations · NCT06273748

• Minocycline treatment for chronic autoimmune uveitis

  This study is testing if minocycline can help people aged 18-60 with chronic autoimmune uveitis reduce inflammation and protect their vision better than current treatments.

  Recruiting Phase 1/2 Sun Yat-sen University · Guangzhou, Guangdong · NCT05474729

• Registry for hereditary autoinflammatory diseases

  This study is collecting information about hereditary autoinflammatory diseases to see how they affect patients of different ages and genders, with the goal of improving treatment and care for everyone affected.

  Recruiting at 112 sites University of Siena · Algiers and 111 other locations · NCT05200715

• Understanding the genetics of uveitis

  This study is trying to find out if there are specific genetic factors in people with uveitis by looking at their blood samples to help improve how we understand and manage the condition.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT02357238

• Using OCT scans to analyze eye inflammation in uveitis patients

  This study is testing if OCT scans can help doctors see and measure eye inflammation in people with uveitis.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT01746537

NIH-funded research (newest 40 of 45)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Adalimumab Dose Adjustment for Pediatric Uveitis in JIA

  A pediatric study will test whether lowering how often kids with juvenile idiopathic arthritis–related uveitis take adalimumab can keep inflammation controlled while reducing side effects and cost.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11523069

• Changing adalimumab dosing for children with juvenile arthritis–related eye inflammation

  This project tries to see if giving lower or less frequent doses of adalimumab can keep eye inflammation under control in children with juvenile idiopathic arthritis.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11523068

• Systemic and topical antiviral treatment for CMV anterior uveitis (STACCATO)

  A new NIH-supported effort will test how well oral and eye-applied antiviral medicines control CMV-related anterior uveitis in affected patients.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11517254

• Systemic and topical antiviral treatment for CMV anterior uveitis in patients

  A patient-friendly look at using antiviral medicines to treat CMV-related eye inflammation and protect vision.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11517253

• Systemic and topical antiviral treatment for CMV anterior uveitis

  This project tests how oral and eye-drop antiviral medicines can help prevent vision loss from CMV-related eye inflammation in people with anterior uveitis.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11517252

• Systemic and topical antiviral control of CMV anterior uveitis: TreatmentOutcomes

  A patient-focused look at how CMV eye inflammation in adults could be treated with pills, eye drops, or other strategies to prevent vision loss.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11517251

• AI tool to standardize how uveitis is measured

  This project builds an AI platform to consistently measure signs of posterior uveitis in lab models so researchers can compare and improve treatments for people with uveitis.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11469605

• Noninvasive imaging endpoints for uveitis readiness

  A planning project to build noninvasive imaging tools and a shared method for measuring inflammation in noninfectious uveitis to prepare for a future trial.

  NIH research University of California at Davis · Davis, United States · NIH-11442820

• NOD2 in T cells helps control uveitis in Blau syndrome

  This grant studies how a human immune system protein (NOD2) in T cells helps prevent dangerous eye inflammation in Blau syndrome patients.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11429582

• Multi-omics approach to improve eye health in uveitis

  Aims to use advanced genetic and molecular testing to better diagnose and predict outcomes for people with uveitis.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11419671

• CDCP1 and autoimmune uveitis: a new target to protect vision

  Researchers are exploring whether CDCP1 helps pathogenic T cells cross the eye’s barriers in autoimmune uveitis and if blocking it could prevent vision loss.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11380823

• Finding eye triggers: how eye B cells reveal what drives uveitis

  A small NIH grant will help scientists use B cells from people with uveitis to find the eye-specific antigens that start inflammation.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11370375

• Understanding how pathogenic CD8 T cells develop in HLA-B27–associated anterior uveitis

  A study in adults with a specific eye inflammation explores how certain immune cells start to cause disease, aiming to uncover new ways to prevent or treat it.

  NIH research Washington University · Saint Louis, United States · NIH-11364905

• In vivo eye imaging to map immune activity in uveitis

  A noninvasive imaging approach in people with uveitis to visualize how immune cells behave in the living eye and how that relates to disease activity.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11345071

• Multidisciplinary telemedicine for chronic pediatric uveitis care

  A telemedicine-based care model connects pediatric eye doctors, rheumatology specialists, and local teams to improve monitoring and treatment for children with chronic uveitis, even in remote areas.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11336621

• Understanding how immune memory drives chronic autoimmune uveitis

  Researchers are studying why chronic autoimmune uveitis persists and causes vision loss, by looking at immune memory cells in a new mouse model that mirrors human disease.

  NIH research Schepens Eye Research Institute · Boston, United States · NIH-11320790

• Improving methotrexate treatment for childhood non-infectious uveitis

  Finding signs that predict which children with chronic non-infectious uveitis will benefit from methotrexate so they can get the right medicine sooner.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11308671

• Therapeutic Drug Monitoring for Personalized Uveitis Care

  A patient-friendly look at using blood tests to tailor adalimumab therapy for non-infectious uveitis to keep vision safer over the long term.

  NIH research Emory University · Atlanta, United States · NIH-11273888

• Systemic and Topical CMV Eye Infection: Treatment Outcomes

  A study to find the best way to treat CMV anterior uveitis, a serious eye infection that can cause blindness, using oral antiviral drugs, eye drops, or observation.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11264266

• A peptide-based test to identify immune causes of uveitis

  This project uses programmable peptide libraries to find antibodies and viral markers in the eye, tears, and blood of adults with anterior uveitis to help pinpoint causes.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11178676

• AI-powered high-resolution eye scans to measure and classify inflammation in uveitis

  This project will use ultrahigh-resolution OCT scans plus deep learning to count and identify inflammatory cells in the eyes of people with uveitis.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11163446

• How the protein CDCP1 helps harmful immune cells enter the eye in autoimmune uveitis

  This project tests whether blocking a protein called CDCP1 can stop damaging immune cells from crossing into the eye in people with autoimmune uveitis.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11132897

• Gut bacteria and immune cells to calm autoimmune uveitis

  Tests whether changing gut bacteria or giving bacterial metabolites can boost immune-regulating cells and reduce eye inflammation for people with autoimmune uveitis.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11123239

• Using genetic and protein tests to better diagnose and treat uveitis

  This project uses advanced microbial and host molecular testing to find causes of uveitis and guide treatment choices for people with eye inflammation.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11118834

• Understanding how immune memory contributes to chronic autoimmune uveitis

  This study is looking into how a specific type of immune cell contributes to chronic autoimmune uveitis, a condition that can cause serious vision problems, using a special mouse model to help find new ways to treat it.

  NIH research Schepens Eye Research Institute · Boston, United States · NIH-11076655

• Developing an AI platform to improve the understanding of autoimmune uveitis

  This study is working on a smart computer program to help doctors better understand and measure autoimmune uveitis, a condition that can affect your vision, so they can find new ways to diagnose and treat it more effectively.

  NIH research University of Tennessee Health Sci Ctr · Memphis, United States · NIH-11063056

• Improving treatment for children with chronic eye inflammation using methotrexate

  This study is looking at how to make methotrexate, a common treatment for kids with a serious eye condition called chronic non-infectious uveitis, work better by figuring out which children are most likely to benefit from it, so they can start the right treatment sooner and protect their vision.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11035096

• Changes in gut bacteria in patients with non-infectious uveitis

  This study is looking at how the bacteria in your gut change over time if you have non-infectious uveitis, and it wants to see if these changes can go back to normal after treatment, helping us understand the link between gut health and eye inflammation.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11033520

• Developing better ways to measure eye inflammation in uveitis

  This study is all about finding better ways to measure eye inflammation caused by uveitis, and it's designed for early career researchers and trainees who want to work with experts to improve how we track and treat this condition.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11000707

• Using advanced techniques to identify causes of uveitis

  This study is looking at how to better diagnose and treat uveitis, a serious eye condition that can cause vision loss, by using new technology to find specific markers in the eye fluids of patients, which could help doctors provide more accurate care.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10993534

• Using advanced imaging and AI to diagnose and classify eye inflammation in uveitis

  This study is looking at how to better diagnose and treat uveitis, a condition that can cause vision loss, by using advanced imaging technology and artificial intelligence to get a clearer picture of inflammation in the eye.

  NIH research Oregon Health & Science University · Portland, United States · NIH-10952558

• Understanding health disparities in uveitis and eye inflammation in the U.S.

  This study looks at how different health challenges can impact uveitis, a condition that can lead to blindness, and aims to find out what makes it worse for different groups of people, while also helping a surgeon learn new skills to better care for patients with uveitis.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-10913463

• Measuring eye inflammation in children with anterior uveitis

  This study is working on better ways to diagnose and track eye inflammation in kids, making it easier for doctors to help them feel better, even if the kids have trouble with regular eye exams.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-10893642

• Investigating the role of gut bacteria and immune cells in autoimmune eye disease

  This study is looking at how the bacteria in your gut might affect autoimmune uveitis, a condition that can cause vision problems, and it hopes to find new ways to help improve eye health by changing gut bacteria through diet and antibiotics.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-10877091

• Investigating how CDCP1 contributes to autoimmune uveitis

  This study is looking at a protein called CDCP1 to see how it affects the movement of harmful T cells in the eye, which could help us find new ways to treat autoimmune uveitis and protect your vision.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-10873898

• Improving diagnosis and treatment of uveitis using advanced technology

  This study is looking at ways to better diagnose and understand uveitis, an eye condition that can cause serious problems, by using advanced technology to find out what might be causing it and how your body is reacting, so we can help doctors take better care of patients like you.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10856815

• Understanding how complement proteins affect autoimmune uveitis

  This study is looking at how certain proteins in the immune system affect a serious eye condition called autoimmune uveitis, which can cause blindness, and it's aimed at finding new ways to help prevent or lessen the impact of this disease.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-10834908

• Understanding how immune responses affect eye inflammation in autoimmune uveitis

  This study is looking at how certain immune cells in the eye might be causing problems in people with autoimmune uveitis, which can lead to vision loss, and it hopes to find new ways to help treat this condition.

  NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-10744201

• Investigating eye inflammation in survivors of Ebola virus disease

  This study is looking at how the Ebola virus can cause eye problems, specifically uveitis, in people who survived Ebola, to help improve their vision and overall well-being.

  NIH research University of Nebraska Medical Center · Omaha, United States · NIH-10667629

• Predicting eye inflammation in children with juvenile arthritis

  This study is looking to help kids with juvenile idiopathic arthritis by finding better ways to spot and treat uveitis, an eye condition they might get, by checking their tears and genes to see who might be at risk.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-10661602

Related topics

Quick answers

How many Uveitis clinical trials are recruiting right now?

10, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 24 countries. The most sites are in United States (4 trials), China (3 trials), Belgium (2 trials), Egypt (2 trials), Greece (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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