Condition

Retinal Degeneration clinical trials and research

• 8Clinical trials
• 4Countries

Newest Retinal Degeneration clinical trials

All recruiting trials (8)

• First-in-human, dose-escalation test of AXV-101 for BBS1-related retinal degeneration

  AXV-101 is tested in children and teens with BBS1 retinal degeneration to see if it is safe, find a good dose, and measure how much drug appears in blood, urine, and tears.

  Recruiting Early Phase 1 Axovia Therapeutics · London · NCT07269665

• Dapagliflozin (an SGLT2 inhibitor) for slowing geographic atrophy in dry AMD

  This trial will test whether taking dapagliflozin once daily can slow the growth of geographic atrophy in people aged 50 and older with dry age-related macular degeneration.

  Recruiting Phase 2 Washington University School of Medicine · St Louis, Missouri · NCT07174687

• Investigating OpCT-001 for treating primary photoreceptor disease

  This study is testing a new treatment called OpCT-001 to see if it can safely help adults with primary photoreceptor diseases, like Retinitis Pigmentosa and Usher Syndrome, improve their vision.

  Recruiting at 5 sites Phase 1/2 BlueRock Therapeutics · Los Angeles, California and 4 other locations · NCT06789445

• Minocycline treatment for chronic autoimmune uveitis

  This study is testing if minocycline can help people aged 18-60 with chronic autoimmune uveitis reduce inflammation and protect their vision better than current treatments.

  Recruiting Phase 1/2 Sun Yat-sen University · Guangzhou, Guangdong · NCT05474729

• Imaging of outer retinal diseases using adaptive optics

  This study is trying to take detailed pictures of the retina in people with outer retinal diseases to help find better ways to diagnose and understand these conditions.

  Recruiting at 2 sites Food and Drug Administration (FDA) · Bethesda, Maryland and 1 other locations · NCT05355415

• Advanced imaging techniques for eye conditions

  This study is testing new advanced imaging techniques to see if they can help doctors better understand and diagnose eye diseases like retinitis pigmentosa and maculopathy.

  Recruiting Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts · Paris · NCT04129021

• Investigating rod and cone function in retinal diseases

  This study is testing how well the light-sensitive cells in the eyes work in people with retinal diseases and healthy volunteers to help understand vision changes in low light.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT02617966

• Collecting cells to study eye diseases

  This study is collecting hair, skin, and blood samples from people with certain eye diseases to see how these conditions develop and find new treatments.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT01432847

Related topics

Quick answers

How many Retinal Degeneration clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (5 trials), China (1 trial), France (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 2, Phase 2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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