Ocular Fluid Work-up in Presumed Trematode-Induced Granulomatous Uveitis
Official title: Ocular Fluid Work-up in Presumed Trematode Induced Granulomatous Uveitis
Run by Kasr El Aini Hospital · NCT07885137 · Data updated 2026-11-12
This study tests ocular fluid samples from patients with presumed trematode-induced granulomatous uveitis who are having eye surgery to look for clues about the cause.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Kasr El Aini Hospital Academic / other |
| Locations | 1 site (Cairo, Giza Governorate) |
| Status | Recruiting |
| Started | September 1, 2026 |
| Main results expected | September 1, 2027 |
| Study ends | December 1, 2027 |
| Registry record updated | October 21, 2026 |
| Trial ID | NCT07885137 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with presumed trematode-induced uveitis scheduled for AC washout or pars plana vitrectomy at Kasr Al-Ainy Hospital, across any age.
✕Probably not a fit
Patients with non-trematode etiologies of granulomatous uveitis or those not undergoing AC washout/PPV may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study will collect clinical data and ocular fluid samples from patients with presumed trematode-induced granulomatous uveitis who are undergoing anterior chamber washout or pars plana vitrectomy at Kasr Al-Aini Ophthalmology Clinic. Researchers will document demographics, disease duration, eye findings, and treatment history, and perform targeted investigations to exclude other causes of granulomatous uveitis. They will record exam results, imaging, and laboratory tests, including AC and vitreous samples for analysis. Data will be analyzed to characterize the clinical presentation and laboratory findings associated with this condition. The goal is to enhance understanding of PTIGU and refine future diagnostic approaches.
Why it matters
Potential benefit: Findings could improve understanding of PTIGU and help guide diagnostic workups for similar patients in the future.
How similar studies have gone: Previous work has explored ocular fluids in granulomatous uveitis broadly, but this exact PTIGU-focused observational approach is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with Presumed Trematode-Induced Uveitis scheduled for AC wash or pars plana vitrectomy of any age. Exclusion Criteria: * Causes of granulomatous uveitis other than trematodal infection. * Inconclusive UBM findings. * Ocular trauma. * Previous ocular surgeries including (anterior chamber wash for AC granulomas).
Where it's running
-
Faculty of Medicine Cairo University Kasr Al Ainy Hospital
Cairo, Giza Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Amnah A Amin, Master degree ophthalmology
- Email: amnah95@hotmail.com
- Phone: 01006371579
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.