Clinical trial Recruiting at 1 site Observational

Ocular Fluid Work-up in Presumed Trematode-Induced Granulomatous Uveitis

Official title: Ocular Fluid Work-up in Presumed Trematode Induced Granulomatous Uveitis

Run by Kasr El Aini Hospital · NCT07885137 · Data updated 2026-11-12

This study tests ocular fluid samples from patients with presumed trematode-induced granulomatous uveitis who are having eye surgery to look for clues about the cause.

More Uveitis trials

Quick facts

Study typeObservational
SexAll
Enrollment40 (estimated)
SponsorKasr El Aini Hospital
Academic / other
Locations1 site (Cairo, Giza Governorate)
StatusRecruiting
StartedSeptember 1, 2026
Main results expectedSeptember 1, 2027
Study endsDecember 1, 2027
Registry record updatedOctober 21, 2026
Trial IDNCT07885137 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with presumed trematode-induced uveitis scheduled for AC washout or pars plana vitrectomy at Kasr Al-Ainy Hospital, across any age.

Probably not a fit

Patients with non-trematode etiologies of granulomatous uveitis or those not undergoing AC washout/PPV may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will collect clinical data and ocular fluid samples from patients with presumed trematode-induced granulomatous uveitis who are undergoing anterior chamber washout or pars plana vitrectomy at Kasr Al-Aini Ophthalmology Clinic. Researchers will document demographics, disease duration, eye findings, and treatment history, and perform targeted investigations to exclude other causes of granulomatous uveitis. They will record exam results, imaging, and laboratory tests, including AC and vitreous samples for analysis. Data will be analyzed to characterize the clinical presentation and laboratory findings associated with this condition. The goal is to enhance understanding of PTIGU and refine future diagnostic approaches.

Why it matters

Potential benefit: Findings could improve understanding of PTIGU and help guide diagnostic workups for similar patients in the future.

How similar studies have gone: Previous work has explored ocular fluids in granulomatous uveitis broadly, but this exact PTIGU-focused observational approach is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with Presumed Trematode-Induced Uveitis scheduled for AC wash or pars plana vitrectomy of any age.

Exclusion Criteria:

* Causes of granulomatous uveitis other than trematodal infection.
* Inconclusive UBM findings.
* Ocular trauma.
* Previous ocular surgeries including (anterior chamber wash for AC granulomas).

Where it's running

  • Faculty of Medicine Cairo University Kasr Al Ainy Hospital
    Cairo, Giza Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.