NIH-funded research R21 grant

Developing an AI platform to improve the understanding of autoimmune uveitis

Official title: A generalizable deep learning platform for unifying quantification of experimental autoimmune uveitis

Funded at University of Tennessee Health Sci Ctr · NIH-11063056 · Data updated 2026-11-12

This study is working on a smart computer program to help doctors better understand and measure autoimmune uveitis, a condition that can affect your vision, so they can find new ways to diagnose and treat it more effectively.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Tennessee Health Sci Ctr
NIH-funded
Lab location1 site (Memphis, United States)
Project startFebruary 1, 2025
Project endJanuary 31, 2027
Funding year2025
Award (this year)$231,000
NIH project number1R21EY036199-01A1
Project IDNIH-11063056 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals, particularly youth and young adults, who are affected by autoimmune uveitis or related conditions.

Less likely to help

Patients with non-autoimmune related eye conditions may not receive benefit from this research.

What this research studies

This research focuses on creating a deep learning platform that aims to unify the quantification of experimental autoimmune uveitis, a condition that can lead to severe visual impairments. By utilizing advanced artificial intelligence techniques, the project seeks to enhance the accuracy and reproducibility of disease assessments, which are currently hampered by variability among observers. The study will leverage animal models to explore the mechanisms of human uveitis and evaluate new therapies. If successful, this approach could lead to better diagnostic methodologies and treatment options for patients suffering from uveitis.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic accuracy and treatment options for patients with autoimmune uveitis.

How similar studies have gone: Other research has shown success in applying AI models in ophthalmology, indicating potential for this novel approach in experimental autoimmune uveitis.

Where this research is happening

  • University of Tennessee Health Sci Ctr
    Memphis, United States
    Active

Researchers

  • Principal investigator: Yousefi, Siamak — University of Tennessee Health Sci Ctr
  • Study coordinator: Yousefi, Siamak

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.