Using OCT scans to analyze eye inflammation in uveitis patients

Automated Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography

Observational The Cleveland Clinic · NCT01746537

This study is testing if OCT scans can help doctors see and measure eye inflammation in people with uveitis.

Quick facts

Study typeObservational
Enrollment1500 (estimated)
SexAll
SponsorThe Cleveland Clinic Academic / other
Locations1 site (Cleveland, Ohio)
Trial IDNCT01746537 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the feasibility of using Optical Coherence Tomography (OCT) scans to assess anterior chamber inflammation in patients diagnosed with uveitis. By conducting a prospective case series, the study will gather data from patients presenting at the Cole Eye Institute. The focus is on evaluating the effectiveness of OCT as a diagnostic tool for monitoring inflammation in the anterior chamber of the eye.

Who should consider this trial

Good fit: Ideal candidates for this study are patients presenting with uveitis at the Cole Eye Institute.

Not a fit: Patients who are unable to provide informed consent or have severe corneal opacities that prevent imaging will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the diagnostic capabilities for uveitis, leading to better management and treatment outcomes for patients.

How similar studies have performed: While this approach is relatively novel, similar studies using OCT for other ocular conditions have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients presenting to Cole Eye Institute with uveitis.

Exclusion Criteria:

* Inability to provide informed consent, including non-English speaking and cognitively/mentally impaired.
* Severe corneal opacities preventing imaging of anterior chamber

Where this trial is running

Cleveland, Ohio

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Uveitis
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.