Uveitis in children under 18
Official title: A Study of Uveitis in Children <18 Years of Age
Run by Jaeb Center for Health Research · NCT07518134 · Data updated 2026-11-12
This project collects medical information from children with uveitis to see how often different types occur and what treatments and clinical features look like.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 17 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Jaeb Center for Health Research Academic / other |
| Locations | 4 sites (Boston, Massachusetts and 3 other locations) |
| Status | Recruiting |
| Started | April 14, 2026 |
| Main results expected | April 1, 2027 |
| Study ends | April 1, 2028 |
| Registry record updated | November 2, 2026 |
| Trial ID | NCT07518134 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children and adolescents under 18 with any non‑traumatic, non‑postoperative uveitis (recent onset ≤6 months or established disease) are eligible to participate.
✕Probably not a fit
Children with traumatic or post‑operative uveitis, bilateral uveitis of differing causes, certain ocular malignancies or inherited retinal degenerations, or those with an immediate family member employed on the study are excluded and would not participate.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational registry enrolling children and teens with any non‑traumatic, non‑postoperative uveitis. Participants complete a single enrollment visit with their doctor, and those with disease onset within 6 months also have a 12‑month chart review to capture early clinical course and treatments. The study records uveitis subtype, demographic and clinical features, and current and past therapies without assigning interventions. Data come from participating pediatric ophthalmology centers to describe frequency and variation across sites and patient groups.
Why it matters
Potential benefit: If successful, the data could help doctors better recognize common pediatric uveitis types and make more informed treatment and monitoring decisions.
How similar studies have gone: Similar observational registries and case series in pediatric uveitis have previously improved epidemiologic and treatment understanding, so this approach is established rather than novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age: * Incident cases (onset ≤ 6 months) \<17 years * Established cases (onset \> 6 months) \<18 years * Diagnosis of any type of uveitis (infectious or noninfectious) in any location except traumatic and post-operative uveitis. * Active or inactive uveitis with any treatment status (current / prior / none \[but under surveillance\]). Exclusion Criteria: * Bilateral uveitis with differing etiologies * Traumatic uveitis * Post-operative uveitis * Immediate family member (spouse, biological or legal guardian, child, sibling, parent) who is an investigative site personnel directly affiliated with this study or who is an employee of JAEB Center for Health Research. * Ocular disease related to Retinoblastoma, Coat's disease, retinitis pigmentosa, inherited retinal degeneration, Juvenile xanthogranuloma (JXG), or leukemia/malignancy within the eye.
Where it's running
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Department of Ophthalmology, Boston University School of Medicine
Boston, Massachusetts, United States Recruiting -
Akron Children's Hospital
Akron, Ohio, United States Recruiting -
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States Recruiting -
Pediatric Ophthalmology Associates, Inc.
Columbus, Ohio, United States Recruiting
Study contacts
- Study coordinator: Julianne Zawadzki, MSPH
- Email: jrobinson@jaeb.org
- Phone: 813-975-8690
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.