Condition

VEXAS Syndrome clinical trials and research

• 5Clinical trials
• 27Countries

Newest VEXAS Syndrome clinical trials

All recruiting trials (5)

• Arumakimig (MAS825) in VEXAS syndrome: 52 weeks to see if it helps people on steroids

  This study tests whether arumakimig can help adults with VEXAS syndrome who are taking glucocorticoids, compared with a placebo, over a year (with an option for a long-term extension).

  Recruiting at 6 sites Phase 2 Novartis · Yokohama, Kanagawa and 5 other locations · NCT07748624

• Assessing the effectiveness of pacritinib for VEXAS syndrome

  This study is testing if the drug pacritinib can help people with VEXAS syndrome manage their symptoms better while reducing their need for steroids.

  Recruiting at 2 sites Phase 2 Swedish Orphan Biovitrum · Scottsdale, Arizona and 38 other locations · NCT06782373

• Using pacritinib to treat VEXAS syndrome

  This study is testing if the drug pacritinib can help people with VEXAS syndrome feel better and manage their symptoms.

  Recruiting Phase 1 Washington University School of Medicine · St Louis, Missouri · NCT06538181

• National registry for patients with VEXAS syndrome

  This study is collecting real-life information from adults with VEXAS syndrome to see how the disease behaves, what treatments work best, and to find important markers for diagnosis.

  Recruiting at 17 sites Technische Universität Dresden · Aachen and 16 other locations · NCT06377462

• Registry for hereditary autoinflammatory diseases

  This study is collecting information about hereditary autoinflammatory diseases to see how they affect patients of different ages and genders, with the goal of improving treatment and care for everyone affected.

  Recruiting at 112 sites University of Siena · Algiers and 111 other locations · NCT05200715

Related topics

Quick answers

How many VEXAS Syndrome clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 27 countries. The most sites are in Germany (3 trials), United States (2 trials), Italy (2 trials), Spain (2 trials), Japan (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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